Arnaud Martin
@evolvwing.bsky.social
Associate Professor of Biology at the George Washington University
Interested in Pattern Formation, Evolutionary Tinkering, Genetics,
#lociofevolution #dnacrobatics #evodevo #lepidoptera
dnacrobatics.com
pubs: https://rb.gy/nfg8p
Interested in Pattern Formation, Evolutionary Tinkering, Genetics,
#lociofevolution #dnacrobatics #evodevo #lepidoptera
dnacrobatics.com
pubs: https://rb.gy/nfg8p
Transgenic Plodia larvae expressing the very bright mBaoJin (mStayGold variant) in its silk glands.
Also some gorgeous 3xP3:mCherry staining of larval ocelli and glia.
(see revised preprint) by pantry moth wizards
@donyaniyaz.bsky.social & @lucalivraghi.bsky.social doi.org/10.1101/2025...
Also some gorgeous 3xP3:mCherry staining of larval ocelli and glia.
(see revised preprint) by pantry moth wizards
@donyaniyaz.bsky.social & @lucalivraghi.bsky.social doi.org/10.1101/2025...
July 19, 2025 at 12:33 PM
Transgenic Plodia larvae expressing the very bright mBaoJin (mStayGold variant) in its silk glands.
Also some gorgeous 3xP3:mCherry staining of larval ocelli and glia.
(see revised preprint) by pantry moth wizards
@donyaniyaz.bsky.social & @lucalivraghi.bsky.social doi.org/10.1101/2025...
Also some gorgeous 3xP3:mCherry staining of larval ocelli and glia.
(see revised preprint) by pantry moth wizards
@donyaniyaz.bsky.social & @lucalivraghi.bsky.social doi.org/10.1101/2025...
Preprint alert from the lab
@jasminealqassar.bsky.social led this elegant study of gene expression in the silk glands of our favorite alternative "silk worm", the pantry moth.
Mega-polyploid cells with thousands of genome copies just to express a handful of proteins
doi.org/10.1101/2025...
@jasminealqassar.bsky.social led this elegant study of gene expression in the silk glands of our favorite alternative "silk worm", the pantry moth.
Mega-polyploid cells with thousands of genome copies just to express a handful of proteins
doi.org/10.1101/2025...
July 17, 2025 at 11:09 AM
Preprint alert from the lab
@jasminealqassar.bsky.social led this elegant study of gene expression in the silk glands of our favorite alternative "silk worm", the pantry moth.
Mega-polyploid cells with thousands of genome copies just to express a handful of proteins
doi.org/10.1101/2025...
@jasminealqassar.bsky.social led this elegant study of gene expression in the silk glands of our favorite alternative "silk worm", the pantry moth.
Mega-polyploid cells with thousands of genome copies just to express a handful of proteins
doi.org/10.1101/2025...
So how Bab is itself repressed in males to allow UV-scales?
Well, to our greatest surprise, it's not: the male state w/ Bab absent every other scale (thus allowing UV) is the default
And instead, females need the Doublesex gene to activate Bab!
crazy CRISPR KOs below (+ IF and RNAi in pape)
5/n
Well, to our greatest surprise, it's not: the male state w/ Bab absent every other scale (thus allowing UV) is the default
And instead, females need the Doublesex gene to activate Bab!
crazy CRISPR KOs below (+ IF and RNAi in pape)
5/n
June 20, 2025 at 3:12 PM
So how Bab is itself repressed in males to allow UV-scales?
Well, to our greatest surprise, it's not: the male state w/ Bab absent every other scale (thus allowing UV) is the default
And instead, females need the Doublesex gene to activate Bab!
crazy CRISPR KOs below (+ IF and RNAi in pape)
5/n
Well, to our greatest surprise, it's not: the male state w/ Bab absent every other scale (thus allowing UV) is the default
And instead, females need the Doublesex gene to activate Bab!
crazy CRISPR KOs below (+ IF and RNAi in pape)
5/n
Our previous study had shown that there is an developmental off switch for this : expression of the transcription factor Bric-a-Brac (bab) blocks the differentiation of UV scales
doi.org/10.1073/pnas...
4/n
doi.org/10.1073/pnas...
4/n
June 20, 2025 at 3:12 PM
Our previous study had shown that there is an developmental off switch for this : expression of the transcription factor Bric-a-Brac (bab) blocks the differentiation of UV scales
doi.org/10.1073/pnas...
4/n
doi.org/10.1073/pnas...
4/n
which is made by male specific ultraviolet-iridescent scales with incredible nanostructures on them
3/n
3/n
June 20, 2025 at 3:12 PM
which is made by male specific ultraviolet-iridescent scales with incredible nanostructures on them
3/n
3/n
Male Orange Sulphur butterflies (Colias eurytheme) use bright ultraviolet flashes during courtship
2/n
2/n
June 20, 2025 at 3:12 PM
Male Orange Sulphur butterflies (Colias eurytheme) use bright ultraviolet flashes during courtship
2/n
2/n
Awesome new paper by @lucalivraghi.bsky.social et al.
doi.org/10.1016/j.cu...
in @currentbiology.bsky.social
on the evo-devo of a butterfly color variation
enjoy the show!
doi.org/10.1016/j.cu...
in @currentbiology.bsky.social
on the evo-devo of a butterfly color variation
enjoy the show!
April 14, 2025 at 2:53 AM
Awesome new paper by @lucalivraghi.bsky.social et al.
doi.org/10.1016/j.cu...
in @currentbiology.bsky.social
on the evo-devo of a butterfly color variation
enjoy the show!
doi.org/10.1016/j.cu...
in @currentbiology.bsky.social
on the evo-devo of a butterfly color variation
enjoy the show!
Yea they're super judgy but their babies less so
April 10, 2025 at 8:42 PM
Yea they're super judgy but their babies less so