Global functioning is used widely to inform treatment and prognosis. In our sample, GF scores were associated with important severity- and course-related variables including hospitalization burden and cognitive performance.

We addressed those gaps using the SUPER-Finland study, which includes linked register data for every single psychiatric hospitalization in Finland since 1969. Global functioning has been assessed routinely at inpatient admission and discharge nationwide since 1994. A peek at the raw GF scores:

Leveraging ~120k GF measures from a complete hospitalization register, we found that higher SZ PGS predicted worse GF at admission & discharge, and less functional improvement during hospitalization. Higher EA PGS predicted better discharge GF and greater improvement, but worse admit GF

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