Background Cognitive-behavioral therapy for avoidant/restrictive food intake disorder (CBT-AR) is an emerging treatment for adults with avoidant/restrictive food intake disorder (ARFID). This articl...

Coming up in Brisbane this July - "Using an enhanced metacognitive model to be an integrative CBT-er" by Assoc Prof Esben Strodl. Have you ever wondered about how to integrate different psy...

The microbiota-gut-brain axis has been proposed as a potential modulator of mood disorders such as major depression. Complex bidirectional biochemical activities in this axis have been posited to part...

Maternal trauma influences infant and adult health outcomes and may impact future generations through epigenetic modifications such as DNA methylation (DNAm). Research in humans on the intergenerational epigenetic transmission of trauma effects is limited. In this study, we assessed DNAm signatures of war-related violence by comparing germline, prenatal, and direct exposures to violence across three generations of Syrian refugees. We compared families in which a pregnant grandmother versus a pregnant mother was exposed to violence and included a control group with no exposure to war. We collected buccal swab samples and survey data from mothers and 1–2 children in each of 48 families (n = 131 participants). Based on an epigenome-wide association study (EWAS), we identified differentially methylated regions (DMPs): 14 were associated with germline and 21 with direct exposure to violence. Most DMPs showed the same directionality in DNAm change across germline, prenatal, and direct exposures, suggesting a common epigenetic response to violence. Additionally, we identified epigenetic age acceleration in association with prenatal exposure to violence in children, highlighting the critical period of in utero development. This is the first report of an intergenerational epigenetic signature of violence, which has important implications for understanding the inheritance of trauma.

Background: Although breastfeeding has been extensively documented to confer health benefits to infants in the early stages of their lives, the sustained influence that it has on autistic traits throu...

The brains of adolescents with depression process information about how others are feeling in a way that is different to those without depression.

Given that research into the treatment of avoidant/restrictive food intake disorder (ARFID) is in its early phases, there is a paucity of evidence-based guidelines directing best practices. However, t...

Incense burning is a significant source of indoor air pollution in many Asian regions. There is emerging evidence that maternal prenatal exposure to incense-burning smoke may be a risk factor for chil...

This study tested the hypothesis that the relationship between faith in God and poor mental health (depression, stress, and anxiety), in higher education students, is mediated by the constructs of ...

ObjectiveThis study aimed to explore the combination effects of prenatal exposure to environment tobacco smoke (ETS) and nutrients supplement during pregnanc...

Research suggests that best-practice psychotherapies only have moderate effects on reducing anxiety in youths. Such limitations in outcomes prompt consideration of alternative conceptualisations of an...

The current approach for diagnosing obesity – one defined solely by an individual’s body mass index – is inadequate.

Scientific Reports - Probiotics and magnesium orotate for the treatment of major depressive disorder: a randomised double blind controlled trial