Hore Lab
@epiotago.bsky.social
Lovers of DNA experimenting with Epigenetics, Developmental Genetics, Genomics and Alternative rDNA. Any vertebrate will do!
Pinned
Hore Lab
@epiotago.bsky.social
· Jan 26
Predicting ‘male-time’ with the Androgen Clock
YouTube video by Epigenetics Otago
youtu.be
Delighted to share our 'Androgen clock' paper in #PNAS ow.ly/Guts50ULghF - the first way to predict long-term androgen exposure using DNA alone. We so much more than the sequence we are born with! Stellar work (and animation - SOUND ON) by Dr Victoria Sugrue youtu.be/GL55yjMalII
Reposted by Hore Lab
1/ I’m very excited to share my postdoc work with @kseskv.bsky.social, in collaboration with @oligriffith.bsky.social. We explore embryonic DNA methylation reprogramming in the fat-tailed dunnart, an Australian marsupial 🦘🌏 www.biorxiv.org/content/10.1...
www.biorxiv.org
November 12, 2025 at 2:57 AM
1/ I’m very excited to share my postdoc work with @kseskv.bsky.social, in collaboration with @oligriffith.bsky.social. We explore embryonic DNA methylation reprogramming in the fat-tailed dunnart, an Australian marsupial 🦘🌏 www.biorxiv.org/content/10.1...
Reposted by Hore Lab
Gutting to see Predator Free 2025 disestablished in the latest budget and rolled into DOC, which in turn is facing its own budget challenges. Lost funding and, more importantly, capacity and capability through this disestablishment makes the goal harder to achieve.
newsroom.co.nz/2025/05/26/i...
newsroom.co.nz/2025/05/26/i...
‘It was a bombshell’: Govt culls pest eradication company
Is the financially stretched Department of Conservation best to lead the country’s cooperative mission to eradicate pests by 2050?
newsroom.co.nz
May 26, 2025 at 8:30 PM
Gutting to see Predator Free 2025 disestablished in the latest budget and rolled into DOC, which in turn is facing its own budget challenges. Lost funding and, more importantly, capacity and capability through this disestablishment makes the goal harder to achieve.
newsroom.co.nz/2025/05/26/i...
newsroom.co.nz/2025/05/26/i...
Delighted to see this high-quality marsupial reprogramming work from @lab-turner.bsky.social and kiwi @bryonyleeke.bsky.social (rdcu.be/emAjn). We also saw muted PGC reprogramming in brushtail possum rdcu.be/emAk5. Same is true for Zebrafish. Maybe eutherians and complete erasure is the outlier?
Divergent DNA methylation dynamics in marsupial and eutherian embryos
Nature - A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.
rdcu.be
May 19, 2025 at 1:39 AM
Delighted to see this high-quality marsupial reprogramming work from @lab-turner.bsky.social and kiwi @bryonyleeke.bsky.social (rdcu.be/emAjn). We also saw muted PGC reprogramming in brushtail possum rdcu.be/emAk5. Same is true for Zebrafish. Maybe eutherians and complete erasure is the outlier?
Reposted by Hore Lab
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature
A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.
www.nature.com
May 14, 2025 at 4:01 PM
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
Fascinating to learn more about the brushtail possum in its home range - and wonderful to see the NZ possum assembly (rdcu.be/ekB2O) helping clarify taxonomy.....Congrats Shelby Middleton, @pezoporus.bsky.social and co-authors
academic.oup.com/zoolinnean/a...
academic.oup.com/zoolinnean/a...
May 4, 2025 at 9:15 AM
Fascinating to learn more about the brushtail possum in its home range - and wonderful to see the NZ possum assembly (rdcu.be/ekB2O) helping clarify taxonomy.....Congrats Shelby Middleton, @pezoporus.bsky.social and co-authors
academic.oup.com/zoolinnean/a...
academic.oup.com/zoolinnean/a...
Reposted by Hore Lab
Australia’s common brushtail possum has long been neglected in terms of its taxonomy. My amazing PhD student Shelby Middleton along with a stellar supervisor team has attempted to resolve this species. Check it here: academic.oup.com/zoolinnean/a...
Revised phylogeography of the common brushtail possum (Trichosurus vulpecula) reveals new insights into genetic structure across Australia
Abstract. Understanding genetic relationships within species is essential for identifying distinct genetic lineages and informing conservation strategies,
academic.oup.com
May 2, 2025 at 1:42 AM
Australia’s common brushtail possum has long been neglected in terms of its taxonomy. My amazing PhD student Shelby Middleton along with a stellar supervisor team has attempted to resolve this species. Check it here: academic.oup.com/zoolinnean/a...
Reposted by Hore Lab
Really proud of @sebasalco.bsky.social's mahi on this one, and grateful to the iwi and hapū who entrusted us with their ngā ika moana taonga. @royalsocietynz.bsky.social, University of Otago, Genomics Aotearoa and ORG.one provided funding, and thanks to all incl coauthors who provided tautoko!
April 8, 2025 at 12:27 AM
Really proud of @sebasalco.bsky.social's mahi on this one, and grateful to the iwi and hapū who entrusted us with their ngā ika moana taonga. @royalsocietynz.bsky.social, University of Otago, Genomics Aotearoa and ORG.one provided funding, and thanks to all incl coauthors who provided tautoko!
Reposted by Hore Lab
Excited to see issue on ribosome heterogeneity and specialisation out @royalsociety.org Philosophical Transactions B. Thanks to authors & co-editors @liamfaller.bsky.social @andershlund.bsky.social Maria Barna. Wonderful cover Bulat Fatkhullin! #ribosomes royalsocietypublishing.org/toc/rstb/202...
Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1921
royalsocietypublishing.org
March 6, 2025 at 2:59 PM
Excited to see issue on ribosome heterogeneity and specialisation out @royalsociety.org Philosophical Transactions B. Thanks to authors & co-editors @liamfaller.bsky.social @andershlund.bsky.social Maria Barna. Wonderful cover Bulat Fatkhullin! #ribosomes royalsocietypublishing.org/toc/rstb/202...
Delighted to share our 'Androgen clock' paper in #PNAS ow.ly/Guts50ULghF - the first way to predict long-term androgen exposure using DNA alone. We so much more than the sequence we are born with! Stellar work (and animation - SOUND ON) by Dr Victoria Sugrue youtu.be/GL55yjMalII
Predicting ‘male-time’ with the Androgen Clock
YouTube video by Epigenetics Otago
youtu.be
January 26, 2025 at 7:00 PM
Delighted to share our 'Androgen clock' paper in #PNAS ow.ly/Guts50ULghF - the first way to predict long-term androgen exposure using DNA alone. We so much more than the sequence we are born with! Stellar work (and animation - SOUND ON) by Dr Victoria Sugrue youtu.be/GL55yjMalII