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epi-bob.bsky.social
@epi-bob.bsky.social
Reposted
Paul Nurse describing the main job of a PI

(From ‘The Thinking Game’, 2024)
October 31, 2025 at 8:45 AM
Reposted
I hate the direction lab equipment design has gone in recent years.

I don't want touchscreens, I don't want wifi integration, I don't want centrifuges demanding to know what time zone they're in.

I just want reliable instruments - with physical buttons - that do the one task they were made for.
January 2, 2025 at 4:29 PM
Reposted
New pre-print alert 🚨 Interested in what @ikafetzo.bsky.social learned about DNA hypomethylation in cancer from investigating surprising gains DNA methylation in DNMT1 KO cells? Read all about it here: www.biorxiv.org/content/10.1...
For a quick summary see this 🧵 1/8 #epigenetics
DNMT1 loss leads to hypermethylation of a subset of late replicating domains by DNMT3A
Loss of DNA methylation is a hallmark of cancer that is proposed to promote carcinogenesis through gene expression alterations, retrotransposon activation and induction of genomic instability. Cancer-...
www.biorxiv.org
January 9, 2025 at 4:53 PM