emmajb001.bsky.social
@emmajb001.bsky.social
Reposted
How much data and resolution do we need to estimate homologous recombination deficiency in breast cancer? Rong Zhu answers this question in our latest paper:

febs.onlinelibrary.wiley.com/doi/full/10....
FEBS Press
This study develops a semi-supervised classifier integrating multi-genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer....
febs.onlinelibrary.wiley.com
April 22, 2025 at 10:59 AM
Reposted
Excited to share our latest work on monitoring response to treatment using ctDNA and shallow WGS using a Bayesian Model developed by Solon Karapanagiotis with @Carloscaldas1960.bsky.social, Emma Beddowes and @mortegaduran.bsky.social

febs.onlinelibrary.wiley.com/doi/full/10....
April 16, 2025 at 7:07 AM
Reposted
New blog posting

A story of precarity at a Russell Group University

There were 25 people employed on the grants; 3 senior research associates, 10 research associates, 6 research assistants & 6 grad students

This is what happened to us

21percent.org?p=1371
January 20, 2025 at 7:56 AM
Reposted
www.nature.com/articles/s41...

Sharing our latest review article to highlight the importance of appropriately developing combination strategies for immune checkpoint therapy. Grateful for working with 3 brilliant scientists: Sangeeta Goswami, Kristen Pauken & Linghua Wang
Next-generation combination approaches for immune checkpoint therapy - Nature Immunology
In this Review, Sharma and colleagues describe the current landscape of combination therapies and discuss requirements for the development of effective combination strategies.
www.nature.com
November 25, 2024 at 8:43 PM