Emily Addington
@emilyaddington.bsky.social
Postdoc in the Roe Lab, Glasgow, working on the genotoxin colibactin. Interested in pathogenic E. coli, the gut microbiome, and CRC. She/Her. 🇧🇲 🏴 🏳️🌈
Reposted by Emily Addington
The most worrisome is that this strain is a well know producer of the colibactin genotoxin, which may be associated with colorectal cancer
bsky.app/profile/them...
bsky.app/profile/them...
New paper:
We show that population exposure to colibactin producing E. coli lineages ST95 and ST73 largely explains global variation in colorectal cancer incidence. Same STs are also major causes of UTIs and may be similarly involved in urinary tract cancers.
www.sciencedirect.com/science/arti...
We show that population exposure to colibactin producing E. coli lineages ST95 and ST73 largely explains global variation in colorectal cancer incidence. Same STs are also major causes of UTIs and may be similarly involved in urinary tract cancers.
www.sciencedirect.com/science/arti...
Geographical variation in the incidence of colorectal cancer and urinary tract cancer is associated with population exposure to colibactin-producing Escherichia coli
Biomedical research has implicated the bacterial metabolite colibactin as a causal risk factor for several cancer types, in particular, colorectal can…
www.sciencedirect.com
February 13, 2025 at 2:29 PM
The most worrisome is that this strain is a well know producer of the colibactin genotoxin, which may be associated with colorectal cancer
bsky.app/profile/them...
bsky.app/profile/them...