Dr Timothy Watts gave an insightful talk on drug allergy, highlighting top anaphylaxis-associated drugs. safe oral tolerance to patent blue V, the value of direct penicillin challenge, SADC in DRESS, and clarified true patterns of beta-lactam cross-reactivity
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Dr Clive Grattan explored chronic urticaria’s mast cell–driven pathogenesis and key CSU endotypes . He highlighted exciting advances with omalizumab, remibrutinib, barzolvolimab, and dupilumab, each showing promising, distinct mechanisms in controlling refractory disease.

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Dr Brockow talked about WALDA (wheat allergy dependent on augmentation factors). cofactors: exercise, strong alcohol, less often aspirin. HWP in cosmetics may trigger later WALDA. Management: education, adrenaline, and gluten avoidance for 4 hours after the cofactors.
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Dr Isabel Skypala highlighted hidden allergens (milk, sunflower seed, insects, pancakes, pasta/pizza, hemp) in idiopathic anaphylaxis. Cofactors like exercise, alcohol, and wheat amplify reactions. Never dismiss food allergy, even if it seems unlikely.

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Dr. Madrigal discussed drug allergy mimics—including CSU, ILO, psychogenic reactions, and infections like Strongyloides mimicking DRESS. Accurate, phenotype-driven evaluation and allergist involvement prevent misdiagnosis, unnecessary avoidance, and optimize patient care.
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Dr. Kolkhir discussed IgE- and MRGPRX2-mediated reactions: IgE drives autoantibodies in AD/CSU; drug allergy testing is limited, often needing provocation. MRGPRX2 causes injection-site/anaphylactoid reactions. Anti-IgE therapy may aid drug administration.

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Dr. Ian Sinha, a paediatric respiratory consultant, stressed how housing and environment affect our health — and can be deadly. He cited the tragic death in Lythgoe, UK: “We felt like the air in our homes was killing us, but we were told we were ‘breathing too much.’”

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