Eugene Makeyev
@emakeyev.bsky.social
We explore the world of RNA in the brain and beyond
Reposted by Eugene Makeyev
Homeostasis! Membranes! Evolution! Yay
Adaptation of eukaryotic membrane homeostasis to species-specific cellular lipid landscapes https://www.biorxiv.org/content/10.1101/2025.11.06.686945v1
November 7, 2025 at 11:29 PM
Homeostasis! Membranes! Evolution! Yay
Our paper describing enhanced hybridization-proximity labeling technology is finally out! Enhanced HyPro can identify proteins associated with small RNA compartments and even some individual transcripts, such as pathological C9orf72 transcripts: www.nature.com/articles/s41...
Enhanced hybridization-proximity labeling discovers protein interactomes of single RNA molecules - Nature Communications
Systematic discovery of proteins interacting with low-abundance RNAs is challenging. Here, the authors develop an enhanced HyPro technology to identify proteins associated with compact RNA compartment...
www.nature.com
October 21, 2025 at 8:46 AM
Our paper describing enhanced hybridization-proximity labeling technology is finally out! Enhanced HyPro can identify proteins associated with small RNA compartments and even some individual transcripts, such as pathological C9orf72 transcripts: www.nature.com/articles/s41...
Reposted by Eugene Makeyev
Happy to share the fully reviewed and revised version of our recent study, where we focus on recurrent mutations in cleavage and polyadenylation sites in tumor suppressor genes. Huge congrats to @ykainov.bsky.social and Fursham Hamid!
doi.org/10.7554/eLif...
doi.org/10.7554/eLif...
Recurrent disruption of tumour suppressor genes in cancer by somatic mutations in cleavage and polyadenylation signals
Somatic mutations frequently disrupt cleavage and polyadenylation signals in tumour suppressor genes in human cancers, likely contributing to tumour progression.
doi.org
December 12, 2024 at 3:09 PM
Happy to share the fully reviewed and revised version of our recent study, where we focus on recurrent mutations in cleavage and polyadenylation sites in tumor suppressor genes. Huge congrats to @ykainov.bsky.social and Fursham Hamid!
doi.org/10.7554/eLif...
doi.org/10.7554/eLif...
If you know someone who might be interested in a PhD project involving collaboration between academia and industry, here is an exciting opportunity in London: www.lido-dtp.ac.uk/apply/apply-.... We have a cool project on antisense oligonucleotide toxicity with AZ this year 😉. Please repost!
November 18, 2024 at 1:59 PM
If you know someone who might be interested in a PhD project involving collaboration between academia and industry, here is an exciting opportunity in London: www.lido-dtp.ac.uk/apply/apply-.... We have a cool project on antisense oligonucleotide toxicity with AZ this year 😉. Please repost!