Previous multiple sclerosis, now the potential role of Epstein Barr virus for driving lupus (SLE)
science.org/doi/10.1126/...
science.org/doi/10.1126/...
November 13, 2025 at 4:41 PM
Our randomized, placebo-controlled trial of tirzepatide (Zepbound) for #LongCovid has already enrolled 500 participants of 1000 planned in less than 2 weeks!
longcovid.scripps.edu/locitt-t/
longcovid.scripps.edu/locitt-t/
LoCITT-T - Long COVID Treatment Trial
The Long COVID Treatment Trial-Tirzepatide (LoCITT-T) is investigating the efficacy of repurposing this drug to treat Long COVID.
longcovid.scripps.edu
November 13, 2025 at 4:40 PM
New strategies for a vexing problem: injectables to the rescue for people with Multidrug-Resistant HIV
✅ Just Accepted
🔗 https://bit.ly/4ovrYCU
✅ Just Accepted
🔗 https://bit.ly/4ovrYCU
November 9, 2025 at 10:57 PM
Pfs230 Domains 7-10 encoded by DNA vaccines induce potent complement-independent transmission-blocking antibody against Plasmodium falciparum.
✅ Just Accepted
🔗 https://bit.ly/3LuGOuD
✅ Just Accepted
🔗 https://bit.ly/3LuGOuD
November 9, 2025 at 10:56 PM
From January to 28 September 2025, over 518K cholera cases and 6,508 deaths have been reported across 32 countries. The deaths have already surpassed last year’s toll.
Read more: bit.ly/432IFwT
Read more: bit.ly/432IFwT
Multi-country outbreak of cholera, external situation report #31 -29 October 2025
Edition 31
bit.ly
October 30, 2025 at 5:12 PM
Insights into the Role of Rifampicin Exposure and Clinical Baseline Covariates on the Response to Pulmonary Tuberculosis Treatment
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3Ws4x0Q
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3Ws4x0Q
October 30, 2025 at 5:11 PM
Acute and chronic viral infections, including Herpes Zoster (Shingles), Hepatitis C, HIV, CMV, influenza, and SARS-CoV-2, are linked with a substantial increased risk of cardiovascular events, from a systematic review. Figure for SARS-CoV-2 below
newsroom.heart.org/news/some-ac...
newsroom.heart.org/news/some-ac...
October 30, 2025 at 5:10 PM
Analysis of antibody markers as immune correlates of risk of severe COVID-19 in the PREVENT-19 efficacy trial of the NVX-CoV2373 recombinant protein vaccine
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3X3UaAs
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3X3UaAs
October 30, 2025 at 5:10 PM
Brain Imaging and Whole Blood Targeted Transcriptomic Analyses to Characterize Cerebral Infarctions in Children With Tuberculous Meningitis
#IDSky
#IDSky
Brain Imaging and Whole Blood Targeted Transcriptomic Analyses to Characterize Cerebral Infarctions in Children With Tuberculous Meningitis
Silent cerebral infarctions are common in children with tuberculous meningitis of mild severity. This study links these infarctions to elevated systemic MM
bit.ly
October 27, 2025 at 1:59 AM
Transmitted HIV-1 Drug Resistance Among Newly Diagnosed Individuals in 31 Provincial-Level Administrative Divisions in China in 2023: A Cross-sectional Survey
#IDSky
#IDSky
Transmitted HIV-1 Drug Resistance Among Newly Diagnosed Individuals in 31 Provincial-Level Administrative Divisions in China in 2023: A Cross-sectional Survey
This study elaborates on transmitted drug resistance (TDR) among antiretroviral therapy–naive people newly diagnosed with HIV in China. It was found that t
bit.ly
October 27, 2025 at 1:58 AM
Ganciclovir Dosing in Premature Infants Receiving Treatment for Congenital Cytomegalovirus Infection: Results of a Prospective Pharmacokinetic Study
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3W7ay2T
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3W7ay2T
October 19, 2025 at 6:21 PM
The gut as a source of infection for fungal pathogens: increased fecal Candida albicans precedes onset of Candida late-onset sepsis in very preterm infants
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
The gut as a source of infection for fungal pathogens: increased fecal Candida albicans precedes onset of Candida late-onset sepsis in very preterm infants
The skin-to-blood route is traditionally considered the main pathway in Candida late-onset sepsis (LOS) development in preterm infants.
bit.ly
October 19, 2025 at 6:20 PM
Insights on recurrent and sequential Clostridioides difficile infections from genomic surveillance in Minnesota, USA, 2019-2021
✅ Just Accepted
#IDSky
🔗 https://bit.ly/46zgcB0
✅ Just Accepted
#IDSky
🔗 https://bit.ly/46zgcB0
October 7, 2025 at 3:05 PM
Time to Reappraise the Antibiotic Treatment for Methicillin-Susceptible Staphylococcus aureus Infective Endocarditis: Data From the Experimental Model
#IDSky
#IDSky
Time to Reappraise the Antibiotic Treatment for Methicillin-Susceptible Staphylococcus aureus Infective Endocarditis: Data From the Experimental Model
Daptomycin in combination with β-lactams significantly improves the activity of monotherapies in sterilizing valve vegetations and in preventing daptomycin
bit.ly
October 7, 2025 at 3:04 PM
Based on the body of evidence, what happens if pregnant women do not receive Covid booster vaccination?
Thousands of hospitalizations of infants and expectant mothers
@nathanlo.bsky.social @peterhotezmdphd.bsky.social
jamanetwork.com/journals/jam...
Thousands of hospitalizations of infants and expectant mothers
@nathanlo.bsky.social @peterhotezmdphd.bsky.social
jamanetwork.com/journals/jam...
October 1, 2025 at 2:29 AM
Children and teens who had a Covid reinfection had a doubling of #LongCovid risk (PASC) and a significant increase in many other adverse outcomes (Figure) www.thelancet.com/journals/lan...
October 1, 2025 at 2:23 AM
Phylogenetic context of antibiotic resistance provides insights into the dynamics of resistance emergence and spread
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4nNjnLc
✅ Just Accepted
#IDSky
🔗 https://bit.ly/4nNjnLc
September 25, 2025 at 1:06 PM
Investigating Azithromycin Activity Against ESBL-Producing Escherichia coli Under Physiologically Relevant Conditions
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3KAnbAM
✅ Just Accepted
#IDSky
🔗 https://bit.ly/3KAnbAM
September 25, 2025 at 1:05 PM
SLC22A1 Resists Hepatitis B Virus by Activating the JAK/STAT Pathway and Predicts the Effect of Pegylated Interferon α–Based Therapy on Chronic Hepatitis B
#IDSky
#IDSky
SLC22A1 Resists Hepatitis B Virus by Activating the JAK/STAT Pathway and Predicts the Effect of Pegylated Interferon α–Based Therapy on Chronic Hepatitis B
The association between SLC22A1 and chronic hepatitis B (CHB) was elucidated. Hepatitis B virus (HBV) down-regulated SLC22A1, which in turn suppressed HBV
bit.ly
September 19, 2025 at 1:39 AM
Efficacy and Safety of WXSH0208 Tablets in Treatment of Acute Uncomplicated Influenza Infection in Adults: A Multicenter Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial
#IDSky
#IDSky
Efficacy and Safety of WXSH0208 Tablets in Treatment of Acute Uncomplicated Influenza Infection in Adults: A Multicenter Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial
WXSH0208 is a selective inhibitor of influenza RNA polymerase subunit, demonstrating antiviral activity in preclinical studies against influenza A and B virus infections.
bit.ly
September 19, 2025 at 1:39 AM
SARS-CoV-2 doesn’t cause new cancers, but worsens outcomes for cancer patients and may trigger recurrence via inflammation.
Long COVID’s chronic inflammatory state could pose future cancer risks—urgent longitudinal studies are needed.
davidlingenfelter.substack.com/p/an-oncolog...
Long COVID’s chronic inflammatory state could pose future cancer risks—urgent longitudinal studies are needed.
davidlingenfelter.substack.com/p/an-oncolog...
September 9, 2025 at 1:31 PM
New mRNA Nanoparticles Target Rickettsial Infections
In an extraordinary leap forward in combating infectious diseases, researchers have unveiled a groundbreaking study focused on the development of mRNA–lipid nanoparticle intrabodies targeting rickettsial infections. This innovative approach…
In an extraordinary leap forward in combating infectious diseases, researchers have unveiled a groundbreaking study focused on the development of mRNA–lipid nanoparticle intrabodies targeting rickettsial infections. This innovative approach…
September 9, 2025 at 1:26 PM
A new study revealed 4 distinct mechanisms through which small molecules can inhibit helicase activity. Through their analysis, they identified key binding pockets that could be targeted for drug discovery and development for cancer and infectious diseases.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
September 9, 2025 at 1:26 PM
A new study revealed 4 distinct mechanisms through which small molecules can inhibit helicase activity. Through their analysis, they identified key binding pockets that could be targeted for drug discovery and development for cancer and infectious diseases.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Structural Chemistry of Helicase Inhibition
Helicases are essential motor enzymes that couple nucleoside-triphosphate hydrolysis with DNA or RNA strand unwinding. Helicases are integral to replication, transcription, splicing, and translation o...
pubs.acs.org
September 3, 2025 at 12:04 PM