We also revealed a previously unknown population heterogeneity in a #Leishmania strain which is commonly used in laboratory research.
We also revealed a previously unknown population heterogeneity in a #Leishmania strain which is commonly used in laboratory research.
In our latest preprint, we combined Semi-permeable capsules ( #SPCs ) with #PTA to sequence the DNA of individual #Leishmania parasites at high throughput, identifying multiple layers of genetic heterogeneity, from mosaic aneuploidy to variations in the sequence of drug-resistance genes.
In our latest preprint, we combined Semi-permeable capsules ( #SPCs ) with #PTA to sequence the DNA of individual #Leishmania parasites at high throughput, identifying multiple layers of genetic heterogeneity, from mosaic aneuploidy to variations in the sequence of drug-resistance genes.
More than 5 years ago we embarked on the journey of using #scDNAseq to study genetic heterogeneity in #Leishmania.
www.nature.com/articles/s41...
More than 5 years ago we embarked on the journey of using #scDNAseq to study genetic heterogeneity in #Leishmania.
www.nature.com/articles/s41...