Ethan Leviss
eleviss.bsky.social
Ethan Leviss
@eleviss.bsky.social
Research Technician in the Kranzusch Lab at DFCI
Reposted by Ethan Leviss
Congratulations to Philip J. Kranzusch, Ph.D., Professor of Cancer Immunology and Virology, who was one of three scientists awarded top honors at the 2025 Blavatnik National Awards for Young Scientists.

Watch to learn more about his work: bit.ly/4pZUDkF
October 8, 2025 at 5:05 PM
Reposted by Ethan Leviss
Excited to share my PhD work in the @kranzuschlab.bsky.social, out now in Molecular Cell @cp-molcell.bsky.social

We discover Acb4, a new family of viral sponges that sequesters nucleotide immune signals and defines molecular features that enable ligand specificity.

www.cell.com/molecular-ce...
A widespread family of viral sponge proteins reveals specific inhibition of nucleotide signals in anti-phage defense
Chang et al. discover anti-CBASS 4 (Acb4), a family of viral sponges that inhibits bacterial immunity by sequestering nucleotide immune signals. Acb4 homologs in phages that infect hosts across all ma...
www.cell.com
August 23, 2025 at 12:21 AM
Reposted by Ethan Leviss
Starting the lab Bluesky account to share a preprint from @aragucci.bsky.social and @sadieantine.bsky.social‬ that reveals molecular principles shared across diverse nuclease-NTPase anti-phage defense systems in bacterial immunity (1/7)

www.biorxiv.org/content/10.1...
Nuclease-NTPase systems use shared molecular features to control bacterial anti-phage defense
Bacteria encode an enormous diversity of defense systems including restriction-modification and CRISPR-Cas that cleave nucleic acid to protect against phage infection. Bioinformatic analyses demonstra...
www.biorxiv.org
July 15, 2025 at 2:25 PM