Eric Kernfeld
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ekernf01.bsky.social
Eric Kernfeld
@ekernf01.bsky.social
Statistician and computational biologist; uw alum; jhu student. He/him. http://ekernf01.github.io
Found it!!
August 13, 2025 at 3:45 PM
August 13, 2025 at 3:26 PM
3) I rode my bike from Washington, DC to Pittsburgh and back, through rain, mud, stiff headwinds, dozens of downed trees, and a couple of sub-freezing nights.
August 13, 2025 at 3:24 PM
What it felt like to write this series:
June 26, 2025 at 1:08 PM
Blogpost: ekernf01.github.io/vanilla

Image credits:
June 26, 2025 at 1:05 PM
BLOG ALERT! 🧬 If you do RNA-seq, ATAC-seq, ChIP-seq, or modeling thereof, you may be overlooking LD score regression methods. These should be standard tools to study genes, variants, and regions en masse, but they are hard to understand. I wrote intros:
June 26, 2025 at 1:03 PM
Help me understand the definition of genetic covariance from the xt-ldsc paper. If beta is an argmax, then isn't cbeta also an argmax for any positive scalar c?
June 23, 2025 at 6:04 PM
There's a lot going on with transcriptome transformers, virtual cells, and perturbation prediction. I updated my recap:
ekernf01.github.io/perturbation...
May 25, 2025 at 8:03 PM
New blog post: pitfalls and open questions in GRN inference, ft. Audrey II.

ekernf01.github.io/guiding-ques...
May 5, 2025 at 4:13 PM
The model also learns that different sets of mutations have different immunogenicity (KRAS vs KRAS/STK).
April 30, 2025 at 1:56 PM
How well does it work? Well, per the report just linked, model has learned that Ifng -> HLA.
April 30, 2025 at 1:55 PM
First, a quick who's-who on Noetik itself, plus a description of the software in their own words.
www.businesswire.com/news/home/20...
April 30, 2025 at 1:53 PM
February 26, 2025 at 2:56 PM
Friday shitpost: I wish biologists would italicize *bona fide* the way we italicize *in vitro*.
February 21, 2025 at 5:51 PM
February 9, 2025 at 6:08 PM
My Ph.D.
February 6, 2025 at 9:22 PM
i knew that *looks sideways*
January 31, 2025 at 4:15 PM
Mean of the training data still absolutely crushing it for perturbation prediction.
www.biorxiv.org/content/10.1...
January 24, 2025 at 12:59 PM
Seeing this in a here's-your-nobel speech makes me a little less embarrassed that I thought transcriptome data might sometimes be causally sufficient.
www.nobelprize.org/prizes/medic...
January 21, 2025 at 7:51 PM
(2/2)
January 13, 2025 at 7:30 PM
I think we can all learn something about persistence from Salgado and Collado-Vides. (1/2)
January 13, 2025 at 7:30 PM
January 8, 2025 at 7:53 PM
Delightful quote from circa 1159AD about kids these days singing *polyphony in church*:

en.wikipedia.org/wiki/Notre-D...

(I'll return to genomics-posting soon, after a short musical interlude.)
December 23, 2024 at 8:02 PM
yadirF tsoptihs: rirrom efil dab, t'not ekam ti!!!

ylsuoires hguoht, t'nod od taht tihs. t'nod tcnitxe em orb.
December 13, 2024 at 3:58 PM
IF they had known the first word was gonna be all caps, they could have rearranged it to be SEGMENTATION instead of ... MUCH!!
November 26, 2024 at 7:11 PM