Erik Hegbom
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ehegbom.bsky.social
Erik Hegbom
@ehegbom.bsky.social
Nephrologist, ESENeph, Levanger hospital, Norway
Reposted by Erik Hegbom
Chat consensus?
🫀Low dose spironolactone is safe in ESRD, but monitor K+
🫀Spironolactone does not decrease CV events or HF hospitalizations in ESRD
🫀No meds (ACEi/statins) have improved CV mortality in ESRD to date; patiently awaiting SGLT2/GLP1/nsMRA studies in ESRD
September 11, 2025 at 2:39 PM
Reposted by Erik Hegbom
ANSWER

💡PTH can increase as early as days after an AKI.

A 1978 study performed serial measurements of PTH in patients with AKI. They found that PTH was elevated within days of injury and returned to normal when renal function recovered.

https://buff.ly/3YKpgxx
November 12, 2024 at 9:13 PM
Reposted by Erik Hegbom
Wrote a blog about it www.nephjc.com/news/2024/10...

I think MRAs in CKD are tricky to use.
You need a tight protocol - not a loosey-goosey pragmatic trial

I still remain a Spiro-stan, but the onus is on us to provide the good data
Finerenone Finally Finishing off Spironolactone? — NephJC
A commentary putting the recent finerenone and spironolactone trials in perspective
www.nephjc.com
November 11, 2024 at 7:33 PM