Edoardo Sozzi
@edo-sozzi.bsky.social
Postdoc @ethz.ch Barbara Treutlein Lab | PhD @Lund university Malin Parmar Lab | Human brain development, single cell sequencing, cell replacement therapy 🧠🧫🧬
Out now in Stem Cell Reports! ✨
In this work we present a 3D co-culture system for the generation of human somatostatin (SST) interneurons 🧠
📄 Read the full paper here:
www.cell.com/stem-cell-re...
In this work we present a 3D co-culture system for the generation of human somatostatin (SST) interneurons 🧠
📄 Read the full paper here:
www.cell.com/stem-cell-re...
Three-dimensional co-culturing reveals human stem cell-derived somatostatin interneurons with subclass expression
Rylander and colleagues present a 3D co-culture model for successful generation and
maturation of somatostatin interneurons from human embryonic stem cells. This system
reveals previously uncharacteri...
www.cell.com
September 12, 2025 at 4:18 PM
Out now in Stem Cell Reports! ✨
In this work we present a 3D co-culture system for the generation of human somatostatin (SST) interneurons 🧠
📄 Read the full paper here:
www.cell.com/stem-cell-re...
In this work we present a 3D co-culture system for the generation of human somatostatin (SST) interneurons 🧠
📄 Read the full paper here:
www.cell.com/stem-cell-re...
🚀 New preprint alert!
We developed a workflow to isolate nuclei from human stem cell-derived grafts in the rat brain for single-nucleus RNA-seq. This approach helps uncover how transplanted progenitors develop into mature neurons in vivo 🌟
Check it out here: www.biorxiv.org/content/10.1...
We developed a workflow to isolate nuclei from human stem cell-derived grafts in the rat brain for single-nucleus RNA-seq. This approach helps uncover how transplanted progenitors develop into mature neurons in vivo 🌟
Check it out here: www.biorxiv.org/content/10.1...
Nuclei Isolation Protocol for Single-Nucleus RNA Sequencing of Human Stem Cell-Derived Grafts
Single-nucleus RNA sequencing enables high-resolution transcriptomic profiling of brain tissue, facilitating detailed analysis of cell identity in models of neurodegeneration and repair. Here, we desc...
www.biorxiv.org
September 8, 2025 at 5:57 PM
🚀 New preprint alert!
We developed a workflow to isolate nuclei from human stem cell-derived grafts in the rat brain for single-nucleus RNA-seq. This approach helps uncover how transplanted progenitors develop into mature neurons in vivo 🌟
Check it out here: www.biorxiv.org/content/10.1...
We developed a workflow to isolate nuclei from human stem cell-derived grafts in the rat brain for single-nucleus RNA-seq. This approach helps uncover how transplanted progenitors develop into mature neurons in vivo 🌟
Check it out here: www.biorxiv.org/content/10.1...
Exciting news in Huntington’s disease research! Transplanted human striatal progenitors can functionally integrate and modulate host brain circuits in a Huntington’s disease animal model - a promising step toward cell based therapy!
Full story: lnkd.in/dzgNb3-R
Full story: lnkd.in/dzgNb3-R
August 26, 2025 at 6:47 AM
Exciting news in Huntington’s disease research! Transplanted human striatal progenitors can functionally integrate and modulate host brain circuits in a Huntington’s disease animal model - a promising step toward cell based therapy!
Full story: lnkd.in/dzgNb3-R
Full story: lnkd.in/dzgNb3-R
6 months ago I defended my PhD thesis, and looking back it feels both close and far away - so much has happened since then! Thanks to everyone who shared this journey with me, especially my supervisors Malin, Alessandro and Daniella, and also my opponent Gonçalo.
Onwards!
Onwards!
August 18, 2025 at 5:15 PM
6 months ago I defended my PhD thesis, and looking back it feels both close and far away - so much has happened since then! Thanks to everyone who shared this journey with me, especially my supervisors Malin, Alessandro and Daniella, and also my opponent Gonçalo.
Onwards!
Onwards!
Reposted by Edoardo Sozzi
How can ventral midbrain #organoid derived from human pluripotent stem cells help to understand the #dopaminergic system and its pathologies?
@fiorenzano.bsky.social and collaborators review recent advances, remaining challenges, and emerging opportunities
www.embopress.org/doi/full/10....
@fiorenzano.bsky.social and collaborators review recent advances, remaining challenges, and emerging opportunities
www.embopress.org/doi/full/10....
July 2, 2025 at 12:01 PM
How can ventral midbrain #organoid derived from human pluripotent stem cells help to understand the #dopaminergic system and its pathologies?
@fiorenzano.bsky.social and collaborators review recent advances, remaining challenges, and emerging opportunities
www.embopress.org/doi/full/10....
@fiorenzano.bsky.social and collaborators review recent advances, remaining challenges, and emerging opportunities
www.embopress.org/doi/full/10....