Isabella Eckerle
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eckerleisabella.bsky.social
Isabella Eckerle
@eckerleisabella.bsky.social
Director, Geneva Centre for Emerging Viral Diseases - Virologist, MD, DTM&H. Interests: Emerging viruses, coronaviruses, diagnostics, translational research for better preparedness for epidemic & pandemic viruses.
Views are my own.
Reposted by Isabella Eckerle
Important read on challenges of continued SARS-CoV-2 surveillance provided by tools like Nextstrain, using GISAID data. Just one comment as someone who is using Nextstrain for my research, for keeping up to date and for scientific talks:
nextstrain.org/blog/2025-11...
Nextstrain: Interruption to GISAID-based SARS-CoV-2 sequence analyses
Nextstrain blog post from 2025-11-06; author(s): Trevor Bedford, Richard Neher and the Nextstrain team
nextstrain.org
November 17, 2025 at 10:37 AM
Reposted by Isabella Eckerle
I want to spell this out in case the implications aren't clear:

This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.

The file allowed this. Cut that - cut off all tools the public & others were using.
On Oct 1, 2025, GISAID informed us that they had ended updates to the flat file of SARS-CoV-2 genomic sequences and associated metadata that we had used to update Nextstrain analyses since Feb 2020. GISAID's stated rationale was that their "resources are limited". 1/5
November 7, 2025 at 2:41 PM
Not great news to see Marburg spreading across the borders of the previously endemic areas. I was so happy to see that Ebola outbreak in the DRC over and now this...I hope the country will be able to get it under control soon.
November 16, 2025 at 11:37 AM
Reposted by Isabella Eckerle
Our lab's paper describing the North American H5N1 epizootic is out now in Nature! So thrilled to have this out, and congratulations to @lambod50.bsky.social for all the fantastic work on this: www.nature.com/articles/s41...
Ecology and spread of the North American H5N1 epizootic - Nature
The panzootic of highly pathogenic H5N1 since 2021 was driven by around nine introductions into the Atlantic and Pacific flyways, followed by rapid dissemination through wild migratory birds, primaril...
www.nature.com
November 12, 2025 at 7:33 PM
Reposted by Isabella Eckerle
Review of literature tidentified 10 reports of 18 cases of asymptomatic infection of humans with H5N1, including 2 cases with molecular and serologic confirmation and 16 cases with molecular confirmation alone. prospective surveillance studies required.
👉 jamanetwork.com/journals/jam...
November 11, 2025 at 6:48 AM
Reposted by Isabella Eckerle
Klimakrise: Erde steuert auf 2,8 Grad Erwärmung zu, Daten des Uno-Umweltprogramms: Der weltweite Klimaschutz reicht den Vereinten Nationen zufolge nicht aus, um die Erderwärmung entscheidend zu bremsen, trotz kleiner Fortschritte. Uno-Generalsekretär António Guterres warnt vor einem »Klimakollaps«.
Klimakrise: Erde steuert auf 2,8 Grad Erwärmung zu, Daten des Uno-Umweltprogramms
Der weltweite Klimaschutz reicht den Vereinten Nationen zufolge nicht aus, um die Erderwärmung entscheidend zu bremsen, trotz kleiner Fortschritte. Uno-Generalsekretär António Guterres warnt vor einem »Klimakollaps«.
www.spiegel.de
November 4, 2025 at 4:30 PM
That would have been big news a few years ago, unfortunately the great science that gives important understanding in coronaviruses is now back to the small circle of scientists. Anyway: A fully functional furin cleavage site in a bat betacorarnavirus! Congrats to the authors!
October 29, 2025 at 9:56 PM
Reposted by Isabella Eckerle
We’ve identified a highly divergent betacoronavirus from South American bat that encodes a functional furin cleavage site.
Another fascinating reminder of how diverse coronavirus evolution is in wildlife reservoirs.
#Virology #VirusEvolution #Bats #Coronavirus

www.biorxiv.org/content/10.1...
A divergent betacoronavirus with a functional furin cleavage site in South American bats
Bats are natural reservoirs for a wide range of RNA viruses. Members of the genus Betacoronavirus, including Severe Acute Respiratory Syndrome virus 2 (SARS-CoV-2) and Middle East Respiratory Syndrome...
www.biorxiv.org
October 27, 2025 at 9:32 PM
Reposted by Isabella Eckerle
EU Parliament pushes for ‘veggie burger’ ban
Unbelievable we are in a climate crisis where meat production is a huge driver of carbon emissions and deforestation
And instead of promoting meat alternatives - they are trying to ban them

www.euractiv.com/news/parliam...
Parliament pushes for ‘veggie burger’ ban | Euractiv
Lawmakers back stricter labelling for meat alternatives
www.euractiv.com
October 8, 2025 at 11:35 AM
Would never ever be possible today and I am quite pessimistic that we will eradicate another human disease in the years (decades?) to come.
who.int WHO @who.int · Aug 28
#ThrowbackThursday: In 1980 the 🌍🌎🌏 was declared #smallpox free, thanks to mass vaccination efforts.

Smallpox was an acute contagious disease caused by the variola virus. It was one of the most devastating diseases known to humanity. #VaccinesWork
August 28, 2025 at 11:04 AM
Reposted by Isabella Eckerle
Wissenschaftler haben eine Fledermausfamilie in Costa Rica per Videokamera beobachtet. Die Tiere wiesen ein reges Sozialverhalten auf, inklusive Begrüßungsritual.
Costa Rica: Fledermäuse beim Umarmen gesichtet
Wissenschaftler haben eine Fledermausfamilie in Costa Rica per Videokamera beobachtet. Die Tiere wiesen ein reges Sozialverhalten auf, inklusive Begrüßungsritual.
www.spiegel.de
August 20, 2025 at 7:45 PM
Our Paper "Evolving infectious disease dynamics shape school-based intervention effectiveness" is finally out in Nature Communications.
www.nature.com/articles/s41...
This work was a great and intensive collaboration and I am incredibly proud of it - what did we do and what did we find?
Evolving infectious disease dynamics shape school-based intervention effectiveness - Nature Communications
School-based non-pharmaceutical interventions were widely used for COVID-19 control. Here, the authors use simulations to investigate how the potential effectiveness of these interventions can vary de...
www.nature.com
July 19, 2025 at 4:38 PM
Ich bin will keinen Kulturkampf in der Politik - ich will eine faire Gesellschaft, eine funktionieren Bahn, keine Kinderarmut, ein funktionierendes Gesundheitssystem, keine Masern, saubere Luft, gut ausgestattete Schulen, Kinderbetreuung, unbelastete Lebensmittel, Fahrradwege, Klimaschutz....
July 16, 2025 at 7:51 PM
Reposted by Isabella Eckerle
Was viele nicht zu verstehen scheinen: Hier wurde ein Drehbuch durchgespielt, mit dem Ziel, eine für die AfD und damit für die schwarz-blaubraunen Träume gewisser Kreise bedrohlich wirkende Richterin zu verhindern und ein nur der AfD nützendes Kulturkampfszenario nach US-Vorbild durchzuziehen.
July 16, 2025 at 8:30 AM
Reposted by Isabella Eckerle
NIUS ist ein komplett künstlich hochgezogenes Propaganda-Medium. Ein Leak hat offenbart, dass sich die Fake-Schleuder nicht selbstständig finanzieren könnte. Sie wird von einem Multimillionär durchgefüttert. Superreiche kaufen sich hier einfach Medienmacht und indoktrinieren damit unsere Politik.
July 15, 2025 at 12:31 PM
Reposted by Isabella Eckerle
Leak bei Nius – und was es neben Namen und Adressen von Abonnenten ernthält: Hans-Georg Maaßen u.a. bekamen im System eine @ vius-Email-Adresse, 46 Nutzer haben Abo für 199,99 Euro Jahresbeitrag abgeschlossen.
Nutzer in Sorge: Hacker stellen Kundendatei von Nius ins Netz
Das Krawallportal "Nius" ist mutmaßlich Ziel einer kriminellen Attacke geworden. Jetzt sorgen sich manche Abonnenten, weil sich über sie so einiges herausfinden lässt.
www.t-online.de
July 15, 2025 at 10:30 AM
Are you an excellent researcher in the field of genomics of infectious diseases of intracellular pathogens (viruses, intracellular parasites or bacteria)? The apply for this chair of excellence at the University of Geneva, Faculty of Medicine:
jobs.unige.ch/www/wd_porta...
Professeur-e ordinaire, professeur-e associé-e (6460)
en génomique des maladies infectieuses intracellulaires Chaire dexcellence / Full Professor or Associate Professor in Genomics of Intracellular Infectious Diseases Chair of Excellence
jobs.unige.ch
July 7, 2025 at 3:51 PM
Congratulations dear Christine!!
Tickets are now available for Professor Christine Goffinet's Inaugural Lecture!

Book now, in Liverpool or online (Wednesday July 16, 5-7pm BST), to hear about her team's cutting-edge research uncovering interactions between viruses and the human host cell.

www.tickettailor.com/events/lstm1....
June 24, 2025 at 8:01 AM
Beautiful light on the beautiful art work in my office this morning. Trying to appreciate the small good things in life in this crazy world right now.
June 24, 2025 at 7:59 AM
Reposted by Isabella Eckerle
4.1% of ready-to-eat #salad bags in Europe may contain #Toxoplasma gondii.

It is recommended to always wash these products before eating, especially for those at risk.

doi.org/10.2807/1560...
Molecular detection of Toxoplasma gondii in ready-to-eat salad mixes: multi-country survey using a validated and harmonised standard operating procedure, Europe, 2021 to 2022
Background Most Toxoplasma gondii infections in humans are considered foodborne, but the relative importance of the various routes of infection is largely unknown. Consumption of green produce contami...
doi.org
June 23, 2025 at 6:42 AM
Reposted by Isabella Eckerle
Just few days left to apply to one of these postdoc positions in my infectious disease modelling Unit at @pasteur.fr in Paris!
June 23, 2025 at 5:24 AM
I will be more active here from now on! :-)
June 23, 2025 at 8:28 AM
Reposted by Isabella Eckerle
The question of the origin of #SARS-CoV-2 is a matter of significant scientific and public interest. Current publicly available data suggests a natural origin, while evidence supporting a lab origin remains scarce. Although no hypothesis has been definitively proven, the available data indicate...
April 9, 2025 at 12:05 PM
Reposted by Isabella Eckerle
Placide Mbala on #mpox in DRC - 4 clades now, 3 circulating - epidemiology has changed - modes of transmission depend more on opportunities than viral change

This symposium on #EmergingViralDisease is exceptional

@gcevd.bsky.social @eckerleisabella.bsky.social @krutikakuppalli.bsky.social
April 8, 2025 at 10:08 AM