Elgin
Elgin
@eakin.bsky.social
Reposted by Elgin
How does fever work?

Our new Science paper shows how elevated body temperature can protect against severe influenza and that avian-origin viruses escape this defence.

This is likely one reason why bird flus and some pandemic influenzas can be so severe.🧵

www.science.org/doi/10.1126/...
Avian-origin influenza A viruses tolerate elevated pyrexic temperatures in mammals
Host body temperature can define a virus’s replicative profile—influenza A viruses (IAVs) adapted to 40° to 42°C in birds are less temperature sensitive in vitro compared with human isolates adapted t...
www.science.org
November 27, 2025 at 7:55 PM
Reposted by Elgin
NIH slashes overheads, fires directors and staff, freezes funds, halts trials, interrupts research, stalls grant review, and terminates 100s of grants on infectious disease, vaccines, mRNA, DEI, LGBTQ health.

NIH director, to Bari Weiss: Scientists are just upset because they didn't vote for Trump.
April 7, 2025 at 12:07 AM
Reposted by Elgin
Breaking: RFK Jr. has forced out PETER MARKS, the nation’s top vaccine regulator.

In his resignation letter, obtained by the Post, Marks said he was willing to work with RFK Jr on his vaccine concerns — but said Kennedy wishes “subservient confirmation of his misinformation and lies.”
RFK Jr. forces out Peter Marks, FDA’s top vaccine scientist
Marks, an architect of Operation Warp Speed, warned that a recent measles outbreak shows how confidence in science and public health is being “undermined.”
www.washingtonpost.com
March 29, 2025 at 1:14 AM
Reposted by Elgin
An atrocious gutting of our collective public health present and future. For detail on #NIH grants cancelled, see our AirTable.

airtable.com/appjhyo9NTvJ...

Numbers different than HHS because of how we handle supplements/subprojects. Unlike DOGE mf'rs, we care about details. Details mean lives.
March 28, 2025 at 9:47 PM
Reposted by Elgin
It's getting late on Friday, so you know what that means: HHS has just updated its list of cancelled grants and programs.

The document went from 14 pages long to 42 pages.

Just an incalculable list of cancelled COVID-19 funding.
taggs.hhs.gov/Content/Data...
taggs.hhs.gov
March 28, 2025 at 8:33 PM
Reposted by Elgin
Welcome to the CEIRR Bluesky account! Check back often for Network updates, like website news, publications, jobs, events, & more. Get integrated on the platform with our CEIRR Starter Pack! go.bsky.app/L8fs4oF

Our first month’s followers will get a shoutout in the new year! #meetCEIRR
December 23, 2024 at 9:31 PM
Reposted by Elgin
Just in time for the holidays, our lab has just submitted our first lab led paper www.biorxiv.org/content/10.1...! We use phylodynamics to reconstruct how H5N1 got to North America and spread so rapidly. Full thread coming post holidays, but for now, super proud of @lambod50.bsky.social
Intensive transmission in wild, migratory birds drove rapid geographic dissemination and repeated spillovers of H5N1 into agriculture in North America
Since late 2021, a panzootic of highly pathogenic H5N1 avian influenza virus has driven significant morbidity and mortality in wild birds, domestic poultry, and mammals. In North America, infections i...
www.biorxiv.org
December 20, 2024 at 10:44 PM
Reposted by Elgin
the tool of the elite bioinformatician
December 10, 2024 at 5:38 PM