Eduardo Esteva
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e-esteva.bsky.social
Eduardo Esteva
@e-esteva.bsky.social
Bioinformatics/socialism/cats
Senior Bioinformatics Programmer, NYU
Reposted by Eduardo Esteva
Wrote a little about what the federal government can actually do logistically to help NYC (and other cities) contend with asylum seeker arrivals, beyond just writing checks or trying (impossibly) to shut down humanitarian migration
Commentary: Biden doesn’t have to pivot to hardline border politics
The president can alleviate the pressure on New York with a national resettlement plan.
www.cityandstateny.com
February 13, 2024 at 9:33 PM
Reposted by Eduardo Esteva
nf-core/airrflow: an adaptive immune receptor repertoire analysis workflow employing the Immcantation framework https://www.biorxiv.org/content/10.1101/2024.01.18.576147v1
nf-core/airrflow: an adaptive immune receptor repertoire analysis workflow employing the Immcantation framework https://www.biorxiv.org/content/10.1101/2024.01.18.576147v1
Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) is a valuable experimental tool to study t
www.biorxiv.org
January 21, 2024 at 8:49 AM
Reposted by Eduardo Esteva
SORBET: Automated cell-neighborhood analysis of spatial transcriptomics or proteomics for interpretable sample classification via GNN https://www.biorxiv.org/content/10.1101/2023.12.30.573739v1
SORBET: Automated cell-neighborhood analysis of spatial transcriptomics or proteomics for interpretable sample classification via GNN https://www.biorxiv.org/content/10.1101/2023.12.30.573739v1
Spatially resolved transcriptomics or proteomics data have the potential to contribute fundamental i
www.biorxiv.org
January 2, 2024 at 1:50 PM
Reposted by Eduardo Esteva
"During the first six weeks of the war in Gaza, Israel routinely used one of its biggest and most destructive bombs in areas it designated safe for civilians, according to an analysis of visual evidence by The New York Times."
A Times Investigation Tracked Israel’s Use of One of Its Most Destructive Bombs in South Gaza
A Times visual investigation reveals that one of Israel’s largest munitions was regularly being dropped in areas designated safe for i
www.nytimes.com
December 22, 2023 at 12:39 PM
Reposted by Eduardo Esteva
Hidden Knowledge Recovery from GAN-generated Single-cell RNA-seq Data https://www.biorxiv.org/content/10.1101/2023.11.27.568840v1
Hidden Knowledge Recovery from GAN-generated Single-cell RNA-seq Data https://www.biorxiv.org/content/10.1101/2023.11.27.568840v1
Background: Machine learning methods have recently been shown powerful in discovering knowledge from
www.biorxiv.org
November 28, 2023 at 2:53 AM
Reposted by Eduardo Esteva
ProTokens: A Machine-Learned Language for Compact and Informative Encoding of Protein 3D Structures https://www.biorxiv.org/content/10.1101/2023.11.27.568722v1
ProTokens: A Machine-Learned Language for Compact and Informative Encoding of Protein 3D Structures https://www.biorxiv.org/content/10.1101/2023.11.27.568722v1
Designing protein structures towards specific functions is of great values for science, industry and
www.biorxiv.org
November 28, 2023 at 2:53 AM
Reposted by Eduardo Esteva
A deep generative model for estimating single-cell RNA splicing and degradation rates https://www.biorxiv.org/content/10.1101/2023.11.25.568659v1
A deep generative model for estimating single-cell RNA splicing and degradation rates https://www.biorxiv.org/content/10.1101/2023.11.25.568659v1
Messenger RNA splicing and degradation kinetics contribute to gene expression regulation, abnormalit
www.biorxiv.org
November 27, 2023 at 2:50 AM
Reposted by Eduardo Esteva
LightRoseTTA: High-efficient and Accurate Protein Structure Prediction Using an Ultra-Lightweight Deep Graph Model https://www.biorxiv.org/content/10.1101/2023.11.20.566676v1
LightRoseTTA: High-efficient and Accurate Protein Structure Prediction Using an Ultra-Lightweight Deep Graph Model https://www.biorxiv.org/content/10.1101/2023.11.20.566676v1
Accurately predicting protein structure, from amino acid sequences to three-dimensional structures,
www.biorxiv.org
November 21, 2023 at 11:54 PM
The perennial struggle between cat, bedsheet, and man
October 24, 2023 at 10:34 PM
Reposted by Eduardo Esteva
Machine Learning Strategies for Improved Phenotype Prediction in Underrepresented Populations https://www.biorxiv.org/content/10.1101/2023.10.12.561949v1
Machine Learning Strategies for Improved Phenotype Prediction in Underrepresented Populations https://www.biorxiv.org/content/10.1101/2023.10.12.561949v1
Precision medicine models often perform better for populations of European ancestry due to the over-
www.biorxiv.org
October 17, 2023 at 12:49 PM
Reposted by Eduardo Esteva
Pan-cancer evolution signatures link clonal expansion to dynamic changes in the tumour immune microenvironment https://www.biorxiv.org/content/10.1101/2023.10.12.560630v1
Pan-cancer evolution signatures link clonal expansion to dynamic changes in the tumour immune microenvironment https://www.biorxiv.org/content/10.1101/2023.10.12.560630v1
Cancer is an evolutionary process characterised by profound intra-tumour heterogeneity. Intra-tumour
www.biorxiv.org
October 14, 2023 at 4:49 AM
Reposted by Eduardo Esteva
ECOD domain classification of 48 whole proteomes from AlphaFold Structure Database using DPAM https://www.biorxiv.org/content/10.1101/2023.10.10.561815v1
ECOD domain classification of 48 whole proteomes from AlphaFold Structure Database using DPAM https://www.biorxiv.org/content/10.1101/2023.10.10.561815v1
Protein structure prediction has now been deployed widely across several different large protein set
www.biorxiv.org
October 14, 2023 at 6:47 AM
The outdoors for all act will allocate funds to build and maintain green spaces, particularly in disadvantaged communities. 1/3 Americans don’t have access to a park or public garden. Higher quality of life starts with the environment

www.rei.com/action/netwo...
October 14, 2023 at 3:33 AM
Reposted by Eduardo Esteva
BatchEval Pipeline: Batch Effect Evaluation Workflow for Multiple Datasets Joint Analysis https://www.biorxiv.org/content/10.1101/2023.10.08.561465v1
BatchEval Pipeline: Batch Effect Evaluation Workflow for Multiple Datasets Joint Analysis https://www.biorxiv.org/content/10.1101/2023.10.08.561465v1
As genomic sequencing technology continues to advance, it becomes increasingly important to perform
www.biorxiv.org
October 10, 2023 at 7:49 PM
Reposted by Eduardo Esteva
GradHC: Highly Reliable Gradual Hash-based Clustering for DNA Storage Systems https://www.biorxiv.org/content/10.1101/2023.10.05.561008v1
GradHC: Highly Reliable Gradual Hash-based Clustering for DNA Storage Systems https://www.biorxiv.org/content/10.1101/2023.10.05.561008v1
As data storage challenges grow and existing technologies approach their limits, synthetic DNA emerg
www.biorxiv.org
October 6, 2023 at 10:47 PM
Reposted by Eduardo Esteva
Characterizing cell-type spatial relationships across length scales in spatially resolved omics data https://www.biorxiv.org/content/10.1101/2023.10.05.560733v1
Characterizing cell-type spatial relationships across length scales in spatially resolved omics data https://www.biorxiv.org/content/10.1101/2023.10.05.560733v1
Spatially resolved omics technologies provide molecular profiling of cells while preserving their or
www.biorxiv.org
October 6, 2023 at 10:47 PM
September 23, 2023 at 11:18 PM
Reposted by Eduardo Esteva
A multimodal Transformer Network for protein-small molecule interactions enhances drug-target affinity and enzyme-substrate predictions https://www.biorxiv.org/content/10.1101/2023.08.21.554147v1
August 22, 2023 at 6:48 PM
Reposted by Eduardo Esteva
Flexiplex: A versatile demultiplexer and search tool for omics data https://www.biorxiv.org/content/10.1101/2023.08.21.554084v1
August 22, 2023 at 3:48 AM
Reposted by Eduardo Esteva
August 21, 2023 at 11:05 PM
Reposted by Eduardo Esteva
We're still hype over the BPRA win in New York! Read more about BPRA and why it's such a critical win towards getting a Green New Deal from coast to coast:

https://jacobin.com/2023/07/new-york-bpra-green-new-deal-public-renewable-energy/
In New York State, Socialists Have Won a Landmark Victory for Green Jobs and Clean Public Power
This spring, socialists and allies in New York State passed legislation empowering the state to build renewable energy and create tens of thousands of good jobs. It can serve as a model for starting t...
jacobin.com
July 9, 2023 at 9:13 PM
Reposted by Eduardo Esteva
mosaicMPI: a framework for modular data integration across cohorts and -omics modalities https://www.biorxiv.org/content/10.1101/2023.08.18.553919v1
August 21, 2023 at 6:47 PM