Dave Weisman
@dweisman.bsky.social
Neurologist, trialist, focused on Alzheimer’s disease.
Skeptical doesn’t mean cynical.
Skeptical doesn’t mean cynical.
Earned that poutine.
October 25, 2025 at 11:41 PM
Earned that poutine.
I love Canada. Got to speak at the CAGP-CCSMH 2025 Annual Scientific Meeting.
October 25, 2025 at 9:53 PM
I love Canada. Got to speak at the CAGP-CCSMH 2025 Annual Scientific Meeting.
Wrapping up Vermont riding.
September 25, 2025 at 1:00 AM
Wrapping up Vermont riding.
The basis of informed consent is falsifying medical records?
July 15, 2025 at 5:00 PM
The basis of informed consent is falsifying medical records?
During and later at red rock.
May 4, 2025 at 5:52 PM
During and later at red rock.
I’m up in the mountains of Denver. Trails going up need oxygen.
May 3, 2025 at 12:09 AM
I’m up in the mountains of Denver. Trails going up need oxygen.
Sigh. Another day, another bad faith (bleed/lede!) news piece about the anti-amyloid drugs.
March 31, 2025 at 9:26 PM
Sigh. Another day, another bad faith (bleed/lede!) news piece about the anti-amyloid drugs.
The ducks are back at Wiss. Good news, more riding.
March 26, 2025 at 3:59 PM
The ducks are back at Wiss. Good news, more riding.
Top 5 for March Madness in the office and, as a bad high school wrestler, know nothing about basketball. Next year Vegas.
March 24, 2025 at 5:29 PM
Top 5 for March Madness in the office and, as a bad high school wrestler, know nothing about basketball. Next year Vegas.
Lecanemab vs. placebo as seen through the eyes of caregiver burden. Great paper. www.sciencedirect.com/science/arti...
February 28, 2025 at 4:10 PM
Lecanemab vs. placebo as seen through the eyes of caregiver burden. Great paper. www.sciencedirect.com/science/arti...
This thread makes me proud to be an American! I'm going to go eat a Whopper, tip generously, then dose an APOE44 patient with lec.
February 26, 2025 at 4:40 PM
This thread makes me proud to be an American! I'm going to go eat a Whopper, tip generously, then dose an APOE44 patient with lec.
I’m about to come back to the US. How’s it going back there?
February 13, 2025 at 11:00 PM
I’m about to come back to the US. How’s it going back there?
I don’t usually leave the office, but got out to Seoul for a few days. Cold but wonderful. Amazing food, people, culture.
February 9, 2025 at 6:46 AM
I don’t usually leave the office, but got out to Seoul for a few days. Cold but wonderful. Amazing food, people, culture.
Tattoo convention with kiddo. We didn’t get any.
January 28, 2025 at 1:34 AM
Tattoo convention with kiddo. We didn’t get any.
WU neg, no UTI, PNA. Head CT below, chased with MRI:
January 18, 2025 at 1:52 PM
WU neg, no UTI, PNA. Head CT below, chased with MRI:
Not to dismiss ARIA's danger, taking n=1 anecdotes over a well done RCT with 850 subjects/wing and balanced deaths is not good faith argument. Myopia ignores the best data to focus on fear mongering.
AD remains fatal. If you saw patients you'd see the risk/benefit.
AD remains fatal. If you saw patients you'd see the risk/benefit.
January 13, 2025 at 3:05 PM
Not to dismiss ARIA's danger, taking n=1 anecdotes over a well done RCT with 850 subjects/wing and balanced deaths is not good faith argument. Myopia ignores the best data to focus on fear mongering.
AD remains fatal. If you saw patients you'd see the risk/benefit.
AD remains fatal. If you saw patients you'd see the risk/benefit.
Patient can’t look up or down. What’s going on?
December 31, 2024 at 4:35 PM
Patient can’t look up or down. What’s going on?
I give to Wikipedia one time a year, then use it all the time. Please consider helping them.
December 30, 2024 at 2:18 AM
I give to Wikipedia one time a year, then use it all the time. Please consider helping them.
Yule eve ride! Wiss has a bit of a snow cover, but it is concrete underneath.
December 24, 2024 at 5:48 PM
Yule eve ride! Wiss has a bit of a snow cover, but it is concrete underneath.
Piller himself misrepresents the impact of AB*56 allegation son the field, so I'm less interested.
If the F vs. M effect was anything other than a subgroup multiple comparison problem (data dredging the other way), then it would be seen across mabs. It isn't. Misusing subgroups is the oops.
If the F vs. M effect was anything other than a subgroup multiple comparison problem (data dredging the other way), then it would be seen across mabs. It isn't. Misusing subgroups is the oops.
December 20, 2024 at 11:28 PM
Piller himself misrepresents the impact of AB*56 allegation son the field, so I'm less interested.
If the F vs. M effect was anything other than a subgroup multiple comparison problem (data dredging the other way), then it would be seen across mabs. It isn't. Misusing subgroups is the oops.
If the F vs. M effect was anything other than a subgroup multiple comparison problem (data dredging the other way), then it would be seen across mabs. It isn't. Misusing subgroups is the oops.
Just got trolled in the best way possible. Lecanemab works.
December 19, 2024 at 8:47 PM
Just got trolled in the best way possible. Lecanemab works.
