@drrgjoneslab.bsky.social
Happy to post about our latest paper on inflammation and Peutz-Jeghers Syndrome (PJS) in Science Advances. Great work by Dr. Shelby Compton! science.org/doi/10.1126/...
IL-17 links the tumor suppressor LKB1 to gastrointestinal inflammation and polyposis
IL-17 is a therapeutic target for intestinal polyposis driven by mutations in the tumor suppressor LKB1.
science.org
June 27, 2025 at 11:41 AM
Happy to post about our latest paper on inflammation and Peutz-Jeghers Syndrome (PJS) in Science Advances. Great work by Dr. Shelby Compton! science.org/doi/10.1126/...
Reposted
IL-17 is a therapeutic target for intestinal polyposis driven by mutations in the tumor suppressor LKB1
www.science.org/doi/10.1126/...
@drrgjoneslab.bsky.social
www.science.org/doi/10.1126/...
@drrgjoneslab.bsky.social
June 20, 2025 at 7:01 PM
IL-17 is a therapeutic target for intestinal polyposis driven by mutations in the tumor suppressor LKB1
www.science.org/doi/10.1126/...
@drrgjoneslab.bsky.social
www.science.org/doi/10.1126/...
@drrgjoneslab.bsky.social
Reposted
Recent study in @science.org by Allen Distinguished Investigator @drrgjoneslab.bsky.social and collaborators examines the role of histone acetylation in T-cell exhaustion.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Nutrient-driven histone code determines exhausted CD8+ T cell fates
Exhausted T cells (TEX) in cancer and chronic viral infections undergo metabolic and epigenetic remodeling, impairing their protective capabilities. However, the impact of nutrient metabolism on epige...
www.science.org
February 17, 2025 at 9:53 PM
Recent study in @science.org by Allen Distinguished Investigator @drrgjoneslab.bsky.social and collaborators examines the role of histone acetylation in T-cell exhaustion.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...