Alexander Li Cohen
@drdrxanderli.bsky.social
ChildNeurologist @BostonChildrens @HarvardMed. Using network imaging to understand/develop new therapies for #autism symptoms. @NIMHgov K23/@SFARIorg BTI Fellow
6️⃣ Yet, amidst uncertainty, the Anterior Cingulate Cortex (ACC) robustly stood out as a region implicated beyond chance and converging with parallel evidence of anatomical changes. This may hint at a critical neural target.
June 17, 2025 at 12:30 PM
6️⃣ Yet, amidst uncertainty, the Anterior Cingulate Cortex (ACC) robustly stood out as a region implicated beyond chance and converging with parallel evidence of anatomical changes. This may hint at a critical neural target.
5️⃣ BUT—crucially—our analyses also found this network pattern was similar to that seen across psychiatric disorders, and that these patterns are similar to what you’d see with randomly chosen brain coordinates!
Meaning: Caution is needed before concluding specificity in coordinate mapping studies.
Meaning: Caution is needed before concluding specificity in coordinate mapping studies.
June 17, 2025 at 12:30 PM
5️⃣ BUT—crucially—our analyses also found this network pattern was similar to that seen across psychiatric disorders, and that these patterns are similar to what you’d see with randomly chosen brain coordinates!
Meaning: Caution is needed before concluding specificity in coordinate mapping studies.
Meaning: Caution is needed before concluding specificity in coordinate mapping studies.
4️⃣ Indeed, we found scattered locations consistently mapped onto brain networks associated with reward processing and cognitive control (Cingulo-Opercular network).
June 17, 2025 at 12:30 PM
4️⃣ Indeed, we found scattered locations consistently mapped onto brain networks associated with reward processing and cognitive control (Cingulo-Opercular network).
3️⃣ Using Coordinate Network Mapping, we asked a new question: could these scattered brain locations converge on common brain networks—even if exact coordinates differ?
June 17, 2025 at 12:30 PM
3️⃣ Using Coordinate Network Mapping, we asked a new question: could these scattered brain locations converge on common brain networks—even if exact coordinates differ?
2️⃣ Why this study?
Do brain imaging studies on anatomical changes in ADHD consistently identify the same brain regions? Surprisingly, our meta-analysis of 38 studies found minimal spatial agreement across studies.
Do brain imaging studies on anatomical changes in ADHD consistently identify the same brain regions? Surprisingly, our meta-analysis of 38 studies found minimal spatial agreement across studies.
June 17, 2025 at 12:30 PM
2️⃣ Why this study?
Do brain imaging studies on anatomical changes in ADHD consistently identify the same brain regions? Surprisingly, our meta-analysis of 38 studies found minimal spatial agreement across studies.
Do brain imaging studies on anatomical changes in ADHD consistently identify the same brain regions? Surprisingly, our meta-analysis of 38 studies found minimal spatial agreement across studies.
@andreashorn_ and @foxmdphd getting a shout out at the Year in Review session at #CNSAM for their work localizing tic networks in the brain!
November 22, 2024 at 9:58 AM
@andreashorn_ and @foxmdphd getting a shout out at the Year in Review session at #CNSAM for their work localizing tic networks in the brain!
The future of @ChildNeuroSoc is bright! Sharing the knowledge with the next generation at the JECF “Finding a Residency/Fellowship/First Job” sessions at the #CNSAM.
Are you a junior faculty member, trainee, or student? Fill out our survey here:...
Are you a junior faculty member, trainee, or student? Fill out our survey here:...
November 22, 2024 at 9:58 AM
The future of @ChildNeuroSoc is bright! Sharing the knowledge with the next generation at the JECF “Finding a Residency/Fellowship/First Job” sessions at the #CNSAM.
Are you a junior faculty member, trainee, or student? Fill out our survey here:...
Are you a junior faculty member, trainee, or student? Fill out our survey here:...
Or, the CNCDP-K12 and MSRP!!!!!
November 22, 2024 at 10:11 AM
Or, the CNCDP-K12 and MSRP!!!!!
“The pipeline is not leaky, it is hemorrhaging! Really we should be applying thrombin.”
November 22, 2024 at 10:05 AM
“The pipeline is not leaky, it is hemorrhaging! Really we should be applying thrombin.”
“The pediatric physician-scientist is an endangered species!” @Brooks_Kayal_MD - winner of the 2023 Bernard Sachs Award #CNSAM @ChildNeuroSoc
November 22, 2024 at 9:58 AM
“The pediatric physician-scientist is an endangered species!” @Brooks_Kayal_MD - winner of the 2023 Bernard Sachs Award #CNSAM @ChildNeuroSoc
@DYTdoc on positively responding to manuscript reviews, and how to strategize your revision @ChildNeuroSoc at the Friday morning Lobby Talks at the #CNSAM
November 22, 2024 at 10:05 AM
@DYTdoc on positively responding to manuscript reviews, and how to strategize your revision @ChildNeuroSoc at the Friday morning Lobby Talks at the #CNSAM
Happy Friday #CNSAM! Come join us this morning for some interesting Junior Member and Early Career lobby talks and this afternoon for the main event: The JECF forum (open to ALL early stage faculty, trainees, and students), with special keynote by CNS President @pbkang7 at 6pm!!!
November 22, 2024 at 10:11 AM
Happy Friday #CNSAM! Come join us this morning for some interesting Junior Member and Early Career lobby talks and this afternoon for the main event: The JECF forum (open to ALL early stage faculty, trainees, and students), with special keynote by CNS President @pbkang7 at 6pm!!!
Final Lobby Talk of the day at #CNSAM: “Creating a Business Plan” by the money whisperer @PedsNeuroMD and how to make taking care of our patients sustainable! @ChildNeuroSoc
November 22, 2024 at 10:11 AM
Final Lobby Talk of the day at #CNSAM: “Creating a Business Plan” by the money whisperer @PedsNeuroMD and how to make taking care of our patients sustainable! @ChildNeuroSoc
Masterclass on plasticity of the developing brain after early acute or chronic injury at #CNSAM by Dr William Gaillard. Winner of this year’s Martha Bridge Denckla Award! @ChildNeuroSoc
November 22, 2024 at 10:11 AM
Masterclass on plasticity of the developing brain after early acute or chronic injury at #CNSAM by Dr William Gaillard. Winner of this year’s Martha Bridge Denckla Award! @ChildNeuroSoc
Happening now at #CNSAM “How to Network at a Meeting” Lobby Talk with April Levin! @ChildNeuroSoc
“Maybe 7 o’clock in the morning isn’t the best time to network at a meeting, but all of you are here so maybe it is!”
“Maybe 7 o’clock in the morning isn’t the best time to network at a meeting, but all of you are here so maybe it is!”
November 22, 2024 at 10:24 AM
Happening now at #CNSAM “How to Network at a Meeting” Lobby Talk with April Levin! @ChildNeuroSoc
“Maybe 7 o’clock in the morning isn’t the best time to network at a meeting, but all of you are here so maybe it is!”
“Maybe 7 o’clock in the morning isn’t the best time to network at a meeting, but all of you are here so maybe it is!”
