dpostrach.bsky.social
@dpostrach.bsky.social
The best way to spark interest in science is by sharing the beauty of microscopy images. I'm excited to see my picture of the intestine featured in the Dutch newspaper 'de Volkskrant'! #microscopy #ScienceArt
January 11, 2025 at 12:28 PM
Our preprint of Polytope is featured in the ISEH preprint watch
The first Preprint Watch for 2025 is plentiful: 9 preprints focusing on Acute Myeloid Leukemia, but also spatial fate mapping meets barcoding, how cell fate decisions occur in hematopoietic progenitors, and more! Read now➡️ simplyblood.org
January 10, 2025 at 1:14 PM
Excited to share our preprint: Polytope, an epitope barcoding system, generating up to 512 unique color codes for in vivo lineage tracing. 🌈🧬 This tech enables spatial fate-mapping with unprecedented clonal and spatial resolution! doi.org/10.1101/2024... #SpatialBiology #LineageTracing #Polytope
Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping
Tracing the fate of individual cells and their progeny remains a challenging task. While imaging-based fate-mapping provides spatial information, it generally lacks complexity due to limited label div...
doi.org
December 3, 2024 at 9:41 AM
Reposted
🎉 Next preprint on its way!
#Polylox #barcoding + computational modelling meets #macrophage #development!

We used 𝐮𝐧𝐛𝐢𝐚𝐬𝐞𝐝 𝐏𝐨𝐥𝐲𝐥𝐨𝐱 𝐛𝐚𝐫𝐜𝐨𝐝𝐢𝐧𝐠 to trace thousands of embryonic progenitor clones and map their development into tissue-specific macrophages.

Happy reading!
doi.org/10.1101/2024...
Holistic genetic barcoding reveals a lineage tree of tissue macrophage development
Tissue macrophages are crucial for organ development and homeostasis, yet the developmental routes leading to tissue macrophages remain controversial. By combining unbiased Polylox barcoding with comp...
doi.org
December 1, 2024 at 11:38 PM
Reposted
Holistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1
Holistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1
Tissue macrophages are crucial for organ development and homeostasis, yet the developmental routes l
www.biorxiv.org
November 30, 2024 at 9:30 PM
Reposted
Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping https://www.biorxiv.org/content/10.1101/2024.11.20.624484v1
Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping https://www.biorxiv.org/content/10.1101/2024.11.20.624484v1
Tracing the fate of individual cells and their progeny remains a challenging task. While imaging-bas
www.biorxiv.org
November 22, 2024 at 12:30 AM