Fred Strathmann
dosusvenom.bsky.social
Fred Strathmann
@dosusvenom.bsky.social
Life Science executive and CLIA Lab Director. Passionate about using technology to solve problems.
Reposted by Fred Strathmann
Still wrestling with sample complexity and poor resolution in your analyses? Our new study shows how ultrahigh resolution ion mobility could streamline biomarker/drug separations. Full paper published in JASMS: pubs.acs.org/doi/10.1021/...

#IonMobility #MassSpec #Bioanalytics #SLIM @asms.org
November 13, 2025 at 3:35 PM
Reposted by Fred Strathmann
The 24th HUPO World Congress is next week in Toronto, Canada. Make sure to add our poster session on how ‘PAMAF Analysis Enables 1,000 Hz Speeds with 100% Ion Utilization for Fast and Sensitive Discovery Workflows’ to your agenda. See you on Tuesday Nov 11, at 1:15pm. #PAMAF #Proteomics #HUPO2025
November 7, 2025 at 2:33 PM
Reposted by Fred Strathmann
New paper from Clemson University shows how our low mass optimized platform delivers faster, more accurate
steroid analysis for challenging low-mass isomers. Read it in JASMS here: pubs.acs.org/doi/10.1021/...

#MOBIE #IonMobility #Steroidomics #MassSpec
Profiling Multiple Steroid Subclasses Enabled by Rounded Turn SLIM Ion Mobility
Ion mobility-mass spectrometry has shown tremendous potential for improving the analysis of various subclasses of steroids. Its speed and ability to separate isobaric and isomeric species makes it id...
pubs.acs.org
October 30, 2025 at 4:29 PM
Reposted by Fred Strathmann
Exciting news! Dr. James Dodds (UNC) will present his year-long work with the #MOBIE system at the upcoming Southeastern and Southwest joint regional meeting of the American Chemical Society. Join his session:
📅Mon, Oct 27 | 🕐1:30 PM | 📍Nautilus A @acs.org
October 24, 2025 at 2:01 PM
Reposted by Fred Strathmann
If there was a certain vendor developing a brand new ion mobility instrument and is in the process of choosing a file format, this is timed incredibly well for them to catch the wave.
I'm a huge fan of this proposal!

If we can get vendor buy-in to an open, common format, it could bring more computational folks into the field. How can these folks be excited about #proteomics when its hard to even read the already complicated data?

pubs.acs.org/doi/10.1021/...
mzPeak: Designing a Scalable, Interoperable, and Future-Ready Mass Spectrometry Data Format
Advances in mass spectrometry (MS) instrumentation, including higher resolution, faster scan speeds, and improved sensitivity, have dramatically increased the data volume and complexity. The adoption of imaging and ion mobility further amplifies these challenges in proteomics, metabolomics, and lipidomics. Current open formats such as mzML and imzML struggle to keep pace due to large file sizes, slow data access, and limited metadata support. Vendor-specific formats offer faster access but lack interoperability and long-term archival guarantees. We here lay the groundwork for mzPeak, a next-generation community data format designed to address these challenges and support high-throughput, multidimensional MS workflows. By adopting a hybrid model that combines efficient binary storage for numerical data and both human- and machine-readable metadata storage, mzPeak will reduce file sizes, accelerate data access, and offer a scalable, adaptable solution for evolving MS technologies. For researchers, mzPeak will support complex workflows and regulatory compliance through faster access, improved metadata, and interoperability. For vendors, it offers a streamlined, open alternative to proprietary formats. mzPeak aims to become a cornerstone of MS data management, enabling sustainable, high-performance solutions for future data types and fostering collaboration across the mass spectrometry community.
pubs.acs.org
October 10, 2025 at 7:09 PM
Reposted by Fred Strathmann
Exploring the dark multi-ome is a crucial step for #genomics, #metabolomics, and #proteomics. Our new article in
@lcgcinternational.bsky.social discusses how new IM-MS tech like SLIM can solve big analytical challenges such as isomeric ambiguity and more: chromatographyonline.com/view/illumin...
October 9, 2025 at 2:01 PM
Reposted by Fred Strathmann
Enantiomer separation is essential for safe drug development. Researchers at Vanderbilt Uni found #HRIM with copper–amino acid complexation on the MOBILion Platform enables true #chiral resolution & #enantiomeric excess quantification. Find out more here: www.mobilionsystems.com/resources/re...
September 24, 2025 at 1:30 PM
Reposted by Fred Strathmann
New paper from Clemson University shows how rounded-turn #SLIM ion mobility system delivers faster, sharper steroid analysis, even for challenging low-mass isomers. Read it in JASMS here: pubs.acs.org/doi/10.1021/...

#MOBIE #IonMobility #Steroidomics #MassSpec
Profiling Multiple Steroid Subclasses Enabled by Rounded Turn SLIM Ion Mobility
Ion mobility-mass spectrometry has shown tremendous potential for improving the analysis of various subclasses of steroids. Its speed and ability to separate isobaric and isomeric species makes it…
pubs.acs.org
September 18, 2025 at 2:04 PM
Every time I cite CDC data in a report, manuscript, or general conversation I have a twinge of concern about how long I’ll be able to do that with confidence. Unless something changes. Or let’s be honest, someone.
September 8, 2025 at 11:02 AM
Reposted by Fred Strathmann
September 7, 2025 at 3:32 PM
Or, they could stay. Stand up for what they believe. Try and use what visibility they have to help stop injustices. But I guess running away so they can enjoy without discomfort is something to be applauded as brave?
September 7, 2025 at 12:29 PM
Reposted by Fred Strathmann
Glad to see it! The blue states are stepping up where the federal government has failed us.
September 5, 2025 at 1:48 PM
Reposted by Fred Strathmann
We need an HHS Secretary who respects science and does not make policy based on conspiracy theories.

Vaccines are safe and effective.

Kennedy is threatening the health of our kids and all Americans.

He must resign.
September 4, 2025 at 7:59 PM
Reposted by Fred Strathmann
Revealing new lipid diversity & structural insights are critical for discovering new diagnostic biomarkers. Read our new Quick Note summarizing research by @vanderbiltusac.bsky.social using high resolution ion mobility: view-su2.highspot.com/viewer/9311a...

#MOBIE #IonMobility #HRIM #Lipids
September 4, 2025 at 2:36 PM
Reposted by Fred Strathmann
Next week we’re attending the first analytica USA in Columbus! Don’t miss our posters and these Sept 11 oral sessions:
▪️Daniel DeBord — HRIM for complex proteomics (11:30–12)
▪️Oliver Schmitz — Exploring coupling Ion Mobility MS and comprehensive 2D-LC (12:30–1)
September 3, 2025 at 1:34 PM
Reposted by Fred Strathmann
Analytica is coming to the US! 🎉 Sept 10–12 in Columbus, OH. Our CTO Daniel DeBord & SVP Frederick Strathmann will share insights on proteomics, exposomics & PAMAF. Register to join us here: analytica-us.com/en/ #proteomics #PAMAF #AnalyticaUSA
August 28, 2025 at 2:57 PM
Reposted by Fred Strathmann
Many MS tools miss big chunks of data but BILLIE™ reveals what others leave unseen, driving deeper protein coverage, faster results, and better insights from even small samples. Proud to be named a Top 5 MS release of 2025 by @biotechniques.bsky.social: www.biotechniques.com/technology-n...
August 27, 2025 at 1:32 PM
"What can I say? CJ's got hooks. That stuff just gets in your head."
Concert outside the White House! #cdnpoli
August 27, 2025 at 6:47 PM
Reposted by Fred Strathmann
Faster drug development starts with better protein characterization. Our PAMAF workflow delivers full sequence coverage + PTM ID in 20 minutes – no compromises needed. Better medicines for improved outcomes. Sign up for BILLIE updates here: go.mobilionsystems.com/BILLIEverVIP #biopharma
August 26, 2025 at 2:28 PM
Reposted by Fred Strathmann
Pretty impressive results. One has to wonder which, internally, is more advanced and ready to be put on an commercially available instrument.
Thermo's in-development IMS or Mobilion's SLIM? If it's the latter, maybe there will be an acquisition.
Enhancing Sensitivity in Low-Load Proteomics Orbitrap Workflows via SLIM Integration pubs.acs.org/doi/10....

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#proteomics #prot-paper
June 11, 2025 at 12:05 PM
Reposted by Fred Strathmann
Spaces are filling up fast for our ASMS breakfast seminars! On Monday June 2nd, we will be joined by Dr. Sarah Choyke from Eurofins Specialty Services for a presentation on driving Advanced #PFAS analysis. Register here: go.mobilionsystems.com/ASMS2025_Bre... #ASMS2025 #MOBIE
May 16, 2025 at 2:01 PM
Reposted by Fred Strathmann
Ready to go backstage with BILLIE?
Join the exclusive MOBILion #BILLIE VIP Club and become a true #BILLIEver. Get front-row access to sneak peeks, early updates, and behind-the-scenes intel before #ASMS2025!

Sign up below: go.mobilionsystems.com/BILLIEverVIP

#Proteomics #PAMAF #MassSpec
April 25, 2025 at 3:40 PM
Reposted by Fred Strathmann
Mark Strynar of the EPA highlights the value of non-targeted analysis in environmental monitoring to detect unknown chemicals missed by traditional methods. Technologies like our MOBIE system provide more confidence for identifications.

Learn more: www.sciencedirect.com/science/arti...
March 20, 2025 at 5:29 PM
Low load is where we shine even more with #PAMAF from @mobilionsystems.bsky.social.
February 25, 2025 at 7:21 PM
Protein IDs for early #PAMAF performance on an Agilent QTOF (fyi - not our final detector) #USHUPO
February 25, 2025 at 7:20 PM