Seth Donoughe
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donoughe.bsky.social
Seth Donoughe
@donoughe.bsky.social
AI+Bio researcher, working to make sure new tech makes the world better.

Also interested in predictive biology, qbio, morphogenesis, evolution, embryos, wings, eggs, dataviz, generative art, illustration

www.sethdonoughe.com
A scanning electron micrograph zoom-in of a single wing scale from a pantry moth (Plodia interpunctella)—you know, the ones in your baking supplies.

Can't wait until somebody discovers how the underlying cell takes on such a wild shape & how the ECM is laid down.

Width of the image is ~8 microns.
December 1, 2024 at 8:55 PM
As insect wings develop, they form "crumpled up" in a very particular way. Unlike origami, there are no crisp folds.

Then, at adulthood, the wings emerge and open up.

Here is a cricket hindwing that I prepped from a juvenile, compared to an adult wing (from Turchyn & Popadić, FEVO 2024) 🧪
November 20, 2024 at 3:37 PM
Geometric order at multiple scales.

This is an optical slice into the eggshell of a fruit fly.

Every dot is the cross-section of a tiny pillar holding up the "roof" that is the outer surface of the egg. The black polygons are cavities left where cellular interfaces used to be. 🧪
November 20, 2024 at 3:18 AM
You know those "veins" on the wings of insects? In some species, they join together with surprisingly complex mechanical linkages.

This is an electron micrograph we captured of a vein joint from a damselfly. Note how the cuticle spikes allow more flexibility in one direction than the other. 🧪
August 4, 2023 at 2:31 PM
A larva of the "lesser house fly" Fannia canicularis, illustrated in the Manual of Nearctic Diptera.

This book has astonishingly detailed and loving drawings of larvae. 🧪
August 2, 2023 at 7:07 PM
~Embryo gymnastics~

In some insect species, the developing embryo does half of a backwards somersault (a movement called "katatrepsis").

Kozo Miyakawa captured this process in a dragonfly in a 1987 paper w/ tons of pen & ink illustrations. 🧪

(freely available: http://aesj.co-site.jp/raiejp.html)
July 12, 2023 at 11:02 PM
Nice! This is the first I've heard of him. Just found some of his amphipod drawings online. These are lovely.
July 11, 2023 at 4:06 PM
The old descriptive embryology papers had some gems of hand-drawn illustration.

These are drawings of the developing embryo of a cabbage white butterfly (Pieris rapae), a species that is often an unwelcome muncher of your kale and bok choy plants.

by L.E.S. Eastham (Phil. Trans. Roy. Soc., 1930) 🧪
July 11, 2023 at 11:12 AM
Tardigrade eggs! 🧪

Some bizarre surfaces on these things. I'm trying (and failing) to imagine the cellular processes that give rise to the branched surface structures. Any ideas? Let me know.

From Vecchi et al 2021: https://jyx.jyu.fi/handle/123456789/75978
July 10, 2023 at 10:49 PM
Portrait of a two-spotted field cricket (Gryllus bimaculatus), taken with my collaborator Taro Nakamura 🧪

No need for chopsticks or fork if you have eating utensils built-in on your face.
July 10, 2023 at 12:02 PM
Wings from a speckle-winged rangeland grasshopper (Arphia conspersa).

This specimen was collected by Wayne Schennum in CO in 1973, & then I recently imaged it at the Chicago Field Museum. Wayne passed away in 2021, leaving a wealth of notes & specimens that are still giving rise to new discoveries.
July 6, 2023 at 4:17 PM