Marie Estock
@dogs-n-dna.bsky.social
loves dogs, scientist, genealogist, crocheter, amateur musician, gamer
Reposted by Marie Estock
Watson – who won the Nobel Prize for his role in divining the structure of DNA; was instrumental in initiating and propelling the Human Genome Project; and who became notorious for his history of racist and sexist comments – has died at 97
Read the full story: go.nature.com/47NJ6wy
Read the full story: go.nature.com/47NJ6wy
November 8, 2025 at 10:24 AM
Watson – who won the Nobel Prize for his role in divining the structure of DNA; was instrumental in initiating and propelling the Human Genome Project; and who became notorious for his history of racist and sexist comments – has died at 97
Read the full story: go.nature.com/47NJ6wy
Read the full story: go.nature.com/47NJ6wy
Happy Mole Day!!!
I'm a bit late with the customary #MoleDay infographic this year, but better late than never!
The mole makes it easier to describe the huge numbers of atoms, molecules, or ions that participate in chemical reactions.
More in this graphic: www.compoundchem.com/2014/10/23/m...
#ChemSky 🧪
The mole makes it easier to describe the huge numbers of atoms, molecules, or ions that participate in chemical reactions.
More in this graphic: www.compoundchem.com/2014/10/23/m...
#ChemSky 🧪
October 24, 2025 at 1:01 AM
Happy Mole Day!!!
Free concert on Sunday!!!
October 24, 2025 at 1:00 AM
Free concert on Sunday!!!
Reposted by Marie Estock
We're firmly into autumn in the Northern Hemisphere, so it's once again time to share one of my favourite chemistry infographics on the kaleidoscope of chemical colours found in autumn leaves! 🍂
www.compoundchem.com/2014/09/11/a...
#ChemSky 🧪
www.compoundchem.com/2014/09/11/a...
#ChemSky 🧪
October 6, 2025 at 7:49 PM
We're firmly into autumn in the Northern Hemisphere, so it's once again time to share one of my favourite chemistry infographics on the kaleidoscope of chemical colours found in autumn leaves! 🍂
www.compoundchem.com/2014/09/11/a...
#ChemSky 🧪
www.compoundchem.com/2014/09/11/a...
#ChemSky 🧪
Reposted by Marie Estock
Maine Dems with video/audio of Susan Collins bragging about how powerful she would be as Appropriations Committee chair...back before she admitted (today) that spending decisions are "above my pay grade." #MEpolitics
September 10, 2025 at 1:49 AM
Maine Dems with video/audio of Susan Collins bragging about how powerful she would be as Appropriations Committee chair...back before she admitted (today) that spending decisions are "above my pay grade." #MEpolitics
Reposted by Marie Estock
A recent #ScienceSignaling study may answer why some patients with triple-negative breast cancer who receive beta-blockers have a lower risk of metastasis and identifies a transcription factor that holds promise as a prognostic and therapeutic target. https://scim.ag/3USXwp5
Hox-C12 coordinates β2-adrenoceptor coupling to a cAMP/calcium feedforward loop to drive invasion in triple-negative breast cancer
A GPCR and a moonlighting transcription factor together drive metastasis in breast cancer.
scim.ag
August 29, 2025 at 3:00 PM
A recent #ScienceSignaling study may answer why some patients with triple-negative breast cancer who receive beta-blockers have a lower risk of metastasis and identifies a transcription factor that holds promise as a prognostic and therapeutic target. https://scim.ag/3USXwp5
Reposted by Marie Estock
August 28, 2025 at 4:48 PM
Reposted by Marie Estock
Scientists are closing in on the ability to apply genome editing to a formidable new target: the human brain
go.nature.com/3UxjvSl
go.nature.com/3UxjvSl
Brain editing now ‘closer to reality’: the gene-altering tools tackling deadly disorders
Stunning results in mice herald gene-editing advances for neurological diseases.
go.nature.com
August 18, 2025 at 9:23 AM
Scientists are closing in on the ability to apply genome editing to a formidable new target: the human brain
go.nature.com/3UxjvSl
go.nature.com/3UxjvSl
Reposted by Marie Estock
Scientists have created a tool that manufactures working proteins directly on the surfaces of cells
go.nature.com/3IMPyv0
go.nature.com/3IMPyv0
SMART tool builds proteins on cell surfaces
Researchers can target effector proteins to cells on the basis of which molecules those cells express.
go.nature.com
July 31, 2025 at 12:20 PM
Scientists have created a tool that manufactures working proteins directly on the surfaces of cells
go.nature.com/3IMPyv0
go.nature.com/3IMPyv0
Reposted by Marie Estock
Two vaccine candidates using mRNA technology elicit a potent immune response against HIV
go.nature.com/4ov7WZI
go.nature.com/4ov7WZI
mRNA vaccines for HIV trigger strong immune response in people
Results from early-stage trial show that 80% of participants who received one of two HIV vaccine candidates produced antibodies against viral proteins.
go.nature.com
August 1, 2025 at 8:40 AM
Two vaccine candidates using mRNA technology elicit a potent immune response against HIV
go.nature.com/4ov7WZI
go.nature.com/4ov7WZI
@tomjumbogrumbo.bsky.social any chance the word can get out about my hometown shelter? They are no kill and need help. www.cleveland19.com/2025/07/23/a...
Ashtabula County Animal Protective League over capacity with 257 pets
ACAPL said 15 more dogs and 25 more cats from various humane cases were brought to the already overcrowded shelter on July 22 alone, bringing the total number of animals in their care to 257. That's m...
www.cleveland19.com
July 24, 2025 at 12:25 PM
@tomjumbogrumbo.bsky.social any chance the word can get out about my hometown shelter? They are no kill and need help. www.cleveland19.com/2025/07/23/a...
Reposted by Marie Estock
ChemDraw turned 40 this week! 🎉
I worked with Revvity Signals to put together this graphic showing how the chemical drawing program has developed from basic beginnings to the integration of features to predict spectra and highlight structural features
wp.me/s4aPLT-chemd...
#ChemSky
I worked with Revvity Signals to put together this graphic showing how the chemical drawing program has developed from basic beginnings to the integration of features to predict spectra and highlight structural features
wp.me/s4aPLT-chemd...
#ChemSky
July 18, 2025 at 8:03 AM
ChemDraw turned 40 this week! 🎉
I worked with Revvity Signals to put together this graphic showing how the chemical drawing program has developed from basic beginnings to the integration of features to predict spectra and highlight structural features
wp.me/s4aPLT-chemd...
#ChemSky
I worked with Revvity Signals to put together this graphic showing how the chemical drawing program has developed from basic beginnings to the integration of features to predict spectra and highlight structural features
wp.me/s4aPLT-chemd...
#ChemSky
So how are we supposed to trust anything that CBS says? Financial decision my ass. Murrow and Cronkite are rolling in their graves.
BREAKING: CBS is canceling "The Late Show," Stephen Colbert tells studio audience. It will end in May 2026.
Stephen Colbert says CBS is ending his 'Late Show' in May 2026
CBS is axing “The Late Show With Stephen Colbert” in May 2026. The announcement on live air Thursday came two days after Colbert spoke out against CBS Global settling with President Donald Trump over a “60 Minutes” story.
bit.ly
July 18, 2025 at 3:22 AM
So how are we supposed to trust anything that CBS says? Financial decision my ass. Murrow and Cronkite are rolling in their graves.
Reposted by Marie Estock
The National Science Foundation has lost its 8-year-old headquarters building to another federal agency as part of President Donald Trump’s campaign to shrink the size of the U.S. government. scim.ag/3HYXNUk
In latest blow, National Science Foundation staff to be booted from their headquarters
Trump administration is giving building to housing department but has not said where science agency will go
scim.ag
June 26, 2025 at 12:52 PM
The National Science Foundation has lost its 8-year-old headquarters building to another federal agency as part of President Donald Trump’s campaign to shrink the size of the U.S. government. scim.ag/3HYXNUk
Reposted by Marie Estock
Name this band: The Four Treasons?
June 24, 2025 at 10:23 PM
Name this band: The Four Treasons?
Reposted by Marie Estock
A US judge has ordered hundreds of terminated research projects at the US National Institutes of Health to be reinstated, calling the processes that led to their cancellation “bereft of reasoning”.
https://go.nature.com/4eeAamP
https://go.nature.com/4eeAamP
Judge rules against NIH grant cuts — and calls them discriminatory
Nature - The decision means that the US biomedical agency has to restore funding to hundreds of research projects, but the government will likely appeal.
go.nature.com
June 21, 2025 at 10:24 PM
A US judge has ordered hundreds of terminated research projects at the US National Institutes of Health to be reinstated, calling the processes that led to their cancellation “bereft of reasoning”.
https://go.nature.com/4eeAamP
https://go.nature.com/4eeAamP
Reposted by Marie Estock
there's always a tweet
June 22, 2025 at 12:37 AM
there's always a tweet
Reposted by Marie Estock
Researchers reveal when boys pull ahead of girls in mathematics, sounding an alarm and providing both an opportunity for schools, parents and researchers.
https://go.nature.com/3ZZpjqJ
https://go.nature.com/3ZZpjqJ
Close the mathematics gender gap: huge study prompts urgent call to action
Researchers reveal when boys pull ahead of girls in mathematics, sounding an alarm and providing both an opportunity for schools, parents and researchers.
go.nature.com
June 11, 2025 at 7:13 PM
Researchers reveal when boys pull ahead of girls in mathematics, sounding an alarm and providing both an opportunity for schools, parents and researchers.
https://go.nature.com/3ZZpjqJ
https://go.nature.com/3ZZpjqJ
Reposted by Marie Estock
Scores of NIH scientists go public to declare their dissent from Trump's deep program cuts and upheaval at their agency.
NIH scientists publish declaration criticizing Trump's deep cuts in public health research
Scores of National Institutes of Health researchers and staffers have come forward to send their Trump-appointed leader a letter challenging policies they say undermine the NIH mission.
bit.ly
June 9, 2025 at 1:30 PM
Scores of NIH scientists go public to declare their dissent from Trump's deep program cuts and upheaval at their agency.
Reposted by Marie Estock
Health Rounds: Older breast cancer patients using estrogen cream live longer, study finds reut.rs/3ZMZI48
Health Rounds: Older breast cancer patients using estrogen cream live longer, study finds
In older women diagnosed with breast cancer, use of estrogen creams to treat menopause symptoms was not only safe but was also linked with longer survival in a large U.S. study.
reut.rs
June 4, 2025 at 1:01 PM
Health Rounds: Older breast cancer patients using estrogen cream live longer, study finds reut.rs/3ZMZI48
Reposted by Marie Estock
As the US National Institutes of Health (NIH) cuts billions of dollars of research grants and contracts, one entity has emerged as the driving force behind these unprecedented changes — billionaire Elon Musk’s US Department of Government Efficiency (DOGE).
https://go.nature.com/4k8TJit
https://go.nature.com/4k8TJit
NIH killed grants on orders from Elon Musk’s DOGE
Court documents and internal correspondence show the cost-cutting force has broad control over the world’s largest public biomedical funder.
go.nature.com
May 21, 2025 at 7:04 PM
As the US National Institutes of Health (NIH) cuts billions of dollars of research grants and contracts, one entity has emerged as the driving force behind these unprecedented changes — billionaire Elon Musk’s US Department of Government Efficiency (DOGE).
https://go.nature.com/4k8TJit
https://go.nature.com/4k8TJit
Reposted by Marie Estock
Nine-and-a-half-month-old K. J. Muldoon, who has a severe form of a rare, life-threatening metabolic disorder, is the first person to receive a bespoke CRISPR gene-editing therapy. cen.acs.org/biological-c... 🧪
A baby gets the world’s first personalized CRISPR therapy
After 3 doses of tailor-made treatment, an infant with a rare, life-threatening urea cycle disorder is thriving
cen.acs.org
May 19, 2025 at 6:37 PM
Nine-and-a-half-month-old K. J. Muldoon, who has a severe form of a rare, life-threatening metabolic disorder, is the first person to receive a bespoke CRISPR gene-editing therapy. cen.acs.org/biological-c... 🧪
Reposted by Marie Estock
Researchers combined two forms of cryo-electron microscopy (cryo-EM) to get atomic-level resolution snapshots of the influenza’s ribonucleoprotein (RNP) complex as it transcribes: cen.acs.org/analytical-c... #chemsky #biosky 🧪
Flu virus transcription caught in the act
Cryo-EM experts make a movie of influenza’s replication machinery, which could lead to better antivirals
cen.acs.org
May 19, 2025 at 6:38 PM
Researchers combined two forms of cryo-electron microscopy (cryo-EM) to get atomic-level resolution snapshots of the influenza’s ribonucleoprotein (RNP) complex as it transcribes: cen.acs.org/analytical-c... #chemsky #biosky 🧪
Reposted by Marie Estock
At least 2,500 applications for research funding have been denied so far this year, more than double the previous two years
https://go.nature.com/4dynTcw
https://go.nature.com/4dynTcw
Exclusive: NIH grant rejections have more than doubled amid Trump chaos
At least 2,500 applications for research funding have been denied so far this year.
go.nature.com
May 19, 2025 at 1:19 PM
At least 2,500 applications for research funding have been denied so far this year, more than double the previous two years
https://go.nature.com/4dynTcw
https://go.nature.com/4dynTcw
Reposted by Marie Estock
The CRISPR family’s most versatile member has made its medical debut: a cutting-edge gene-editing technique known as prime editing has been used to treat a person for the first time
https://go.nature.com/3YNta9V
https://go.nature.com/3YNta9V
World first: ultra-powerful CRISPR treatment trialled in a person
Immune-cell function improved in a teenager whose DNA was altered using prime editing.
go.nature.com
May 19, 2025 at 1:58 PM
The CRISPR family’s most versatile member has made its medical debut: a cutting-edge gene-editing technique known as prime editing has been used to treat a person for the first time
https://go.nature.com/3YNta9V
https://go.nature.com/3YNta9V