Dobbek Lab, Humboldt-Universitaet zu Berlin, Germany
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dobbek-lab.bsky.social
Dobbek Lab, Humboldt-Universitaet zu Berlin, Germany
@dobbek-lab.bsky.social
Structural Enzymology Lab, X-ray crystallography, Metalloenzymes
Terrible to see how easy science is destroyed
October 21, 2025 at 8:49 PM
Reposted by Dobbek Lab, Humboldt-Universitaet zu Berlin, Germany
The #UniSysCat scientists Holger Dobbek @dobbek-lab.bsky.social (@humboldtuni.bsky.social) & Christian Lorent & Ingo Zebger (@tuberlin.bsky.social) showed how the flexibility of the nickel ion in the active site makes it the key player in CO₂ activation & conversion.

www.nature.com/articles/s41...
Metalloradical-driven enzymatic CO2 reduction by a dynamic Ni–Fe cluster - Nature Catalysis
The mechanism by which the [NiFe4S4] cluster of carbon monoxide dehydrogenases (CODHs) catalyses CO2 reduction is poorly understood. Now the structures of all catalytically relevant states of a CODH a...
www.nature.com
August 7, 2025 at 10:57 AM