"Capturing the Electrical Activity of all Cortical Neurons:
Are Solutions Within Reach?" in Advanced Science, link to the paper: doi.org/10.1002/advs... 5/5

#neurotechnology #neuralinterfaces #iBCI #neuralink #invasive #electrophysiology #clinical #electrode #systemsneuroscience #highdensity

Although there has been some discussion about this recently (E.g., the #Science Corp. mentions it in their update: science.xyz/news/biohybr... ), we are making the first attempt to systematically assess the BN of the best available probes (high-density rigid, flexible, and biohybrid electrodes). 4/5

In close connection with this, we are introducing the term “ #Butcher_Number ” in the literature as a valuable parameter for assessing insertion-related damage and acute recording quality (first mentioned by #Markus_Meister @mameister4.bsky.social whom we thank for the term in the paper). 3/5

But scaling this is far from trivial. What are the theoretical and practical limits for #BCIs interfacing with the neural tissue? We are exploring this in our recent review, led by #Gergely_Katona (co-first-authored by #Attila_Kaszas and me), together with other brilliant members from our lab. 2/5

Is the word pope not P.O.P.U.S in Latin, by any chance?:)

The coolest result, IMO, is active prediction of upcoming words in the sequence, suggesting that hippocampus is involved in the process of using information about current words to predict future words, even in the absence of consciousness.

All Credit goes to first and last authors, I am just a co-author:) thank you for reposting!

Here, our team have conducted the longest and most thorough evaluation available on the electrical and material performance of chronic implantable bare-die and PDMS-coated CMOS chips.

www.nature.com/articles/s41...

Could you please add me, if still possible? We are doing high-density in vivo human Neuropixels recording in the OR!:) thanks!

Could you please add me as well, if still possible? We are doing high-density intraoperative Neuropixels recordings in human, single unit, LFP, cognitive tasks all involved, thanks!

I would like to join too, working on human in vivo single unit and LFP analysis!:)