Derek J Wilson
@derekjwilson.bsky.social
Professor: Mass spectrometry, protein dynamics, (millisecond) hydrogen deuterium exchange, conformational disorder... and more! All at York University in Toronto, Canada.
I should add - because I have been known to complain about peer review lately - that the peer review on this particular work was excellent, resulting substantial improvement. Our thanks to 'reviewer #2' in particular... ...
May 14, 2025 at 11:29 PM
I should add - because I have been known to complain about peer review lately - that the peer review on this particular work was excellent, resulting substantial improvement. Our thanks to 'reviewer #2' in particular... ...
Was it York? That sounds like something our 'advancement' office would do...
February 11, 2025 at 2:08 PM
Was it York? That sounds like something our 'advancement' office would do...
Yep, and here's why :)... journals.plos.org/plosone/arti...
Hyperphosphorylation of Intrinsically Disordered Tau Protein Induces an Amyloidogenic Shift in Its Conformational Ensemble
Tau is an intrinsically disordered protein (IDP) whose primary physiological role is to stabilize microtubules in neuronal axons at all stages of development. In Alzheimer's and other tauopathies, tau...
journals.plos.org
December 29, 2024 at 1:28 PM
Yep, and here's why :)... journals.plos.org/plosone/arti...
Sharks with frickin lazers on their heads! :)
December 13, 2024 at 12:54 PM
Sharks with frickin lazers on their heads! :)
What would this animation look like if reviewers were *paid* I wonder?
December 11, 2024 at 7:18 PM
What would this animation look like if reviewers were *paid* I wonder?
Not the shortest trek for you, but... Next time!!
December 9, 2024 at 3:31 AM
Not the shortest trek for you, but... Next time!!
December 8, 2024 at 11:15 PM
More seriously, there have been many great talks, but one that stood out for me was Elvin Cabrera (Barran group) coming up with ways to do fast, high resolution IMS + FT Charge detection MS on HUGE protein complexes. Super amazing stuff!
December 6, 2024 at 5:29 PM
More seriously, there have been many great talks, but one that stood out for me was Elvin Cabrera (Barran group) coming up with ways to do fast, high resolution IMS + FT Charge detection MS on HUGE protein complexes. Super amazing stuff!
There was one Tal where I learned that my drinking water may be contaminated with the remnants of poop. It would be a depressing thought except... ... ...
December 6, 2024 at 3:48 PM
There was one Tal where I learned that my drinking water may be contaminated with the remnants of poop. It would be a depressing thought except... ... ...
December 6, 2024 at 1:52 PM
December 5, 2024 at 10:22 PM
Don't know... But I think it has something to do with Facebook not crashing...
December 5, 2024 at 7:20 PM
Don't know... But I think it has something to do with Facebook not crashing...
...And another critical point. For pedagogy not to subsidize research (which I agree, it shouldn't), tricouncil needs to *substantially increase the indirect cost %* that they pay when profs get funded. In the US, overhead % is *much* higher, driving unis to actually compete for research grants.
December 1, 2024 at 4:46 PM
...And another critical point. For pedagogy not to subsidize research (which I agree, it shouldn't), tricouncil needs to *substantially increase the indirect cost %* that they pay when profs get funded. In the US, overhead % is *much* higher, driving unis to actually compete for research grants.
I think this is already happening (or has already happened) at many institutions. Even at my relatively 'research light' institution, genuinely research oriented profs rarely teach below 3rd year now. This accompanies the rise of 'alt stream' professors whose job explicitly focuses on pedagogy.
December 1, 2024 at 4:42 PM
I think this is already happening (or has already happened) at many institutions. Even at my relatively 'research light' institution, genuinely research oriented profs rarely teach below 3rd year now. This accompanies the rise of 'alt stream' professors whose job explicitly focuses on pedagogy.