Olson Lab
@deolsonlab.bsky.social
Check out our latest paper in Nature Neuroscience (rdcu.be/ey7yk). This was a great collaboration with some very surprising results! Seems that a glutamate burst and proximate IEG expression might not be necessary for structural neuroplasticity induced by 5-HT2A partial agonists.
August 5, 2025 at 12:52 PM
Check out our latest paper in Nature Neuroscience (rdcu.be/ey7yk). This was a great collaboration with some very surprising results! Seems that a glutamate burst and proximate IEG expression might not be necessary for structural neuroplasticity induced by 5-HT2A partial agonists.
I love all of our papers equally, but I might love this one a bit more. Rare to see complex molecule total synthesis, molecular neuroscience, and behavioral neuropharmacology in the same paper! Special thanks to all of of the students and our collaborators who helped make this work possible
The #UCDavisIPN's latest article in @pnas.org is out now. By transposing just 2 atoms in LSD, we synthesized JRT, a non-hallucinogenic analogue. Read about this and how the compound could be used as a potential treatment for schizophrenia here: www.pnas.org/doi/epub/10....
Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential
www.pnas.org
April 14, 2025 at 7:33 PM
I love all of our papers equally, but I might love this one a bit more. Rare to see complex molecule total synthesis, molecular neuroscience, and behavioral neuropharmacology in the same paper! Special thanks to all of of the students and our collaborators who helped make this work possible
Reposted by Olson Lab
Check out IPN Director @deolsonlab.bsky.social on NPR's Short Wave podcast. Part 1 gives an introduction to the breadth of psychedelic research and is out now. Stay tuned for part 3, where David discusses IPN research in more detail. Listen wherever you get your podcasts or at this link:
Why it's hard to study the neuroscience of psychedelics : Short Wave
Researchers are studying psychedelics as a possible treatment for conditions like depression, PTSD and substance use disorders. But they don't know exactly how these drugs work. Getting the answer to ...
www.npr.org
April 7, 2025 at 8:04 PM
Check out IPN Director @deolsonlab.bsky.social on NPR's Short Wave podcast. Part 1 gives an introduction to the breadth of psychedelic research and is out now. Stay tuned for part 3, where David discusses IPN research in more detail. Listen wherever you get your podcasts or at this link:
Reposted by Olson Lab
We’re excited to announce that @ucdavisipn.bsky.social has been accepted to compete in #STATMadness! A bracketed competition from @statnews.com to find the most innovative research institution in the country! Round one ends this weekend - vote now!
Learn more at www.statnews.com/feature/stat...
Learn more at www.statnews.com/feature/stat...
March 5, 2025 at 9:36 PM
We’re excited to announce that @ucdavisipn.bsky.social has been accepted to compete in #STATMadness! A bracketed competition from @statnews.com to find the most innovative research institution in the country! Round one ends this weekend - vote now!
Learn more at www.statnews.com/feature/stat...
Learn more at www.statnews.com/feature/stat...
Reposted by Olson Lab
We wrote a short News & View piece to highlight the exciting work by Tina Kim and @deolsonlab.bsky.social at @ucdavisipn.bsky.social. Novel neuron-tagging techniques used to dissect the mechanism of psychedelics ⚡🧠🤯
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Could psychedelics be fine-tuned to relieve anxiety but skip the ‘trip’?
Pinpointing neurons that mediate psychedelics' beneficial effects.
www.nature.com
February 19, 2025 at 12:08 PM
We wrote a short News & View piece to highlight the exciting work by Tina Kim and @deolsonlab.bsky.social at @ucdavisipn.bsky.social. Novel neuron-tagging techniques used to dissect the mechanism of psychedelics ⚡🧠🤯
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Vote for UC Davis in STAT Madness!!!
Vote for the #UCDavisIPN in the first round of @statnews.com's #STATMadness here: www.statnews.com/feature/stat.... Please help us show the world we're the best in biomedical research this year!
March 3, 2025 at 9:59 PM
Vote for UC Davis in STAT Madness!!!
Check out our ibogaine total synthesis in @NatureChemistry! This was a tough project that took nearly a decade to complete by @UCDavisIPN researchers.
Includes the synthesis of the unnatural enantiomer of ibogaine and ibogaine analogues that modulate SERT
www.nature.com/articles/s41...
Includes the synthesis of the unnatural enantiomer of ibogaine and ibogaine analogues that modulate SERT
www.nature.com/articles/s41...
Efficient and modular synthesis of ibogaine and related alkaloids - Nature Chemistry
Preliminary clinical trials suggest that ibogaine and its active metabolite noribogaine have powerful anti-addictive properties, Now, a strategy for the scalable, asymmetric total synthesis of ibogain...
www.nature.com
February 8, 2025 at 2:30 PM
Check out our ibogaine total synthesis in @NatureChemistry! This was a tough project that took nearly a decade to complete by @UCDavisIPN researchers.
Includes the synthesis of the unnatural enantiomer of ibogaine and ibogaine analogues that modulate SERT
www.nature.com/articles/s41...
Includes the synthesis of the unnatural enantiomer of ibogaine and ibogaine analogues that modulate SERT
www.nature.com/articles/s41...