Denise Cheah
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denisecheah.bsky.social
Denise Cheah
@denisecheah.bsky.social
MSc at UZH 🧬👽🪐
My favourite question: why is life?
Reposted by Denise Cheah
1/46 Hey folks, we have a new paper out on the MuLTEE. Strap in and I’ll tell you the story of how this “little paper on polyploidy” turned into the most data rich paper our lab has produced, largely thanks to the leadership and work ethic of @kaitong25.bsky.social.

www.nature.com/articles/s41...
Genome duplication in a long-term multicellularity evolution experiment - Nature
In the Multicellularity Long Term Evolution Experiment, diploid yeast evolve to be tetraploid under selection for larger multicellular size, revealing how whole-genome duplication can arise due to its...
www.nature.com
March 5, 2025 at 11:00 PM
Reposted by Denise Cheah
Amazing effort and results. I have been wondering when someone would confirm experimentally what has been predicted by Kashtan, Noor & @urialonlab.bsky.social (www.pnas.org/doi/full/10....), and similar papers from that time.

Experimental evolution of evolvability www.science.org/doi/10.1126/...
Experimental evolution of evolvability
Evolvability—the capacity to generate adaptive variation—is a trait that can itself evolve through natural selection. However, the idea that mutation can become biased toward adaptive outcomes remains...
www.science.org
February 24, 2025 at 9:14 AM