Dennis Frank
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denfra.bsky.social
Dennis Frank
@denfra.bsky.social
PhD student in Freiburg and meme enthusiast
Reposted by Dennis Frank
It was inspiring and fun hosting Patrick Lusk @luskinglab.bsky.social as our seminar guest, here looking at cell nuclei and peppers with AFM expert Dennis @denfra.bsky.social
November 17, 2025 at 3:00 PM
Reposted by Dennis Frank
Svenja Ulferts @sulferts.bsky.social receiving a wonderful doctoral thesis award from our @uni-freiburg.de president 🥳🍾 - well done and well deserved!
October 22, 2025 at 2:43 PM
Reposted by Dennis Frank
we found that nuclear envelope rupture triggers rapid DIAPH3 formin influx to generate a actin mesh to prevent further chromatin leakage from damaged nuclei. thanks to Pitter Huesgen @degradomics.bsky.social and @cibss.bsky.social, @chrkam.bsky.social
September 22, 2025 at 11:00 AM
Reposted by Dennis Frank
Nuclear rupture in confined cell migration triggers nuclear actin polymerization to limit chromatin leakage
DDR sensor ATR protects against nuclear envelope rupture via formin phosphorylation inducing F-actin formation
Christos Kamaras et al @grosselab.bsky.social
www.embopress.org/doi/full/10....
September 22, 2025 at 9:04 AM
Reposted by Dennis Frank
Hi all, check out our new preprint where we uncover:"Regulation of YAP activity by nuclear G-actin binding", www.biorxiv.org/cgi/content/...
#actin #YAP/TAZ #transcription #nucleus with help from Sonja-Verena Albers
‪@archaellum.bsky.social‬
Regulation of YAP activity by nuclear G-actin binding
The Yes-associated protein YAP belongs to the TEAD (TEA/ATTS domain) transcriptional co-activators that shuttle between cytoplasm and nuclear compartment. YAP and its paralog TAZ (transcriptional co-a...
www.biorxiv.org
July 31, 2025 at 6:34 AM