Deegan Lab
@deeganlab.bsky.social
Research group at MRC Human Genetics Unit in Edinburgh working on DNA replication (https://institute-genetics-cancer.ed.ac.uk/research/research-groups-a-z/deegan-group)
Application deadline is this Friday!
Exciting opportunity to join us as a PhD student and kickstart cryo-EM studies in our group 🔬🧬. Includes world class training opportunities @mdc-berlin.bsky.social and @uoe-igc.bsky.social. See below for more details and please get in touch if you're interested.
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Structures and mechanisms of genome replication at University of Edinburgh on FindAPhD.com
PhD Project - Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Structures and mechanisms of genome replication at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
May 12, 2025 at 2:35 PM
Application deadline is this Friday!
Exciting opportunity to join us as a PhD student and kickstart cryo-EM studies in our group 🔬🧬. Includes world class training opportunities @mdc-berlin.bsky.social and @uoe-igc.bsky.social. See below for more details and please get in touch if you're interested.
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Structures and mechanisms of genome replication at University of Edinburgh on FindAPhD.com
PhD Project - Fully Funded PhD Studentship in Human Genetics, Genomics and Disease: Structures and mechanisms of genome replication at University of Edinburgh, listed on FindAPhD.com
www.findaphd.com
April 15, 2025 at 12:30 PM
Exciting opportunity to join us as a PhD student and kickstart cryo-EM studies in our group 🔬🧬. Includes world class training opportunities @mdc-berlin.bsky.social and @uoe-igc.bsky.social. See below for more details and please get in touch if you're interested.
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
3rd edition of the fantastic UK DNA replication meeting is happening next September in Edinburgh. Don't miss out 🧬🏴
www.biochemistry.org/events-and-t...
www.biochemistry.org/events-and-t...
UK DNA Replication Meeting 2026
Research in the DNA replication field is progressing at a remarkable rate. Technological innovations in biochemical reconstitution, structural biology, proteomics and DNA sequencing are helping to rap...
www.biochemistry.org
April 15, 2025 at 10:30 AM
3rd edition of the fantastic UK DNA replication meeting is happening next September in Edinburgh. Don't miss out 🧬🏴
www.biochemistry.org/events-and-t...
www.biochemistry.org/events-and-t...
Two weeks left to apply for this PhD opportunity in our group. Informal enquiries welcome.
4-year PhD studentship available in my lab to study helper helicase function in eukaryotic DNA replication. Happy to receive any enquiries directly to me. Come join us and add your figure to the lab lego collection!
institute-genetics-cancer.ed.ac.uk/igc-graduate...
institute-genetics-cancer.ed.ac.uk/igc-graduate...
April 14, 2025 at 1:38 PM
Two weeks left to apply for this PhD opportunity in our group. Informal enquiries welcome.
Reposted by Deegan Lab
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
DNA replication and genome maintenance: from basic biology to disease
www.embl.org
February 26, 2025 at 3:22 PM
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
4-year PhD studentship available in my lab to study helper helicase function in eukaryotic DNA replication. Happy to receive any enquiries directly to me. Come join us and add your figure to the lab lego collection!
institute-genetics-cancer.ed.ac.uk/igc-graduate...
institute-genetics-cancer.ed.ac.uk/igc-graduate...
February 7, 2025 at 11:42 AM
4-year PhD studentship available in my lab to study helper helicase function in eukaryotic DNA replication. Happy to receive any enquiries directly to me. Come join us and add your figure to the lab lego collection!
institute-genetics-cancer.ed.ac.uk/igc-graduate...
institute-genetics-cancer.ed.ac.uk/igc-graduate...
Congratulations Francesca. And looking forward to your seminar in Edinburgh later this week!
What if science truly is like volleyball, where teamwork and support are everything? We spoke with @fmattiroli.bsky.social, who recently earned tenure, to explore this question and more. Read her inspiring story here 👇 www.hubrecht.eu/francesca-ma...
Francesca Mattiroli got tenure: ‘Science is a team sport’ - Hubrecht Institute
She always dreamed of becoming a scientist. Francesca Mattiroli, has passed tenure evaluation with flying colors. She will expand her chromatin research.
www.hubrecht.eu
January 21, 2025 at 2:25 PM
Congratulations Francesca. And looking forward to your seminar in Edinburgh later this week!
Reposted by Deegan Lab
A huge thanks to Ryo Fujisawa for joining our JC this week!
Ryo's formidable work on TTF2 from his recent article "TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Polε" was enlightening. Great scientific discussion!
Ryo's work doi.org/10.1101/2024...
Ryo's formidable work on TTF2 from his recent article "TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Polε" was enlightening. Great scientific discussion!
Ryo's work doi.org/10.1101/2024...
TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Polε
Mammalian cells frequently enter mitosis before DNA replication has finished, necessitating the rapid processing of replication forks to facilitate chromosome segregation. The TRAIP ubiquitin ligase i...
doi.org
January 16, 2025 at 1:57 PM
A huge thanks to Ryo Fujisawa for joining our JC this week!
Ryo's formidable work on TTF2 from his recent article "TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Polε" was enlightening. Great scientific discussion!
Ryo's work doi.org/10.1101/2024...
Ryo's formidable work on TTF2 from his recent article "TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Polε" was enlightening. Great scientific discussion!
Ryo's work doi.org/10.1101/2024...
Reposted by Deegan Lab
Anti-venom spat out of a computer ! Thank you David Baker !
De novo designed proteins neutralize lethal snake venom toxins - Nature
Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible an...
www.nature.com
January 15, 2025 at 7:50 PM
Anti-venom spat out of a computer ! Thank you David Baker !
Beautiful work from the Douglas lab. Give it a read!
Really cool work, demonstrating TRF2-RAP1 mediated inhibition of the NHEJ machinery at chromosome ends!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Chromosome end protection by RAP1-mediated inhibition of DNA-PK
During classical non-homologous end joining (cNHEJ), DNA-dependent protein kinase (DNA-PK) encapsulates free DNA ends, forming a recruitment platform for downstream end-joining factors including Ligas...
www.biorxiv.org
January 6, 2025 at 11:28 AM
Beautiful work from the Douglas lab. Give it a read!