David A. Sinclair, Ph.D.
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davidsinclairphd.bsky.social
David A. Sinclair, Ph.D.
@davidsinclairphd.bsky.social
Professor @Harvard researching why we age & how to reverse it. Author & host of Lifespan. Mission: Extend healthy life for all. Views are entirely his own 🙏✌️
Grateful for the leadership of President. Jeffrey Tsai at Asia University and so excited for what’s ahead 🚀
Press release:
tinyurl.com/fdn8ckd9
Asia University Partners with NucleicAI to Build a Sovereign AI Life Science Data Platform
/PRNewswire/ -- Asia University will partner with NucleicAI LLC, a next-generation platform and data company specializing in AI-driven genomics, precision...
tinyurl.com
October 15, 2025 at 11:30 PM
Dr. Haghighi is Chief Executive and Director, Harvard Medical School International Center for Genetic Disease, Principal Investigator and Director, Bahrain National Genome Program at Harvard and Assistant Professor of Medicine, Harvard Medical School, and Brigham and Women's Hospital
October 15, 2025 at 11:30 PM
This is more than a regional milestone. It reflects our broader commitment to working with governments, academia, and industry worldwide to responsibly unlock the full potential of genomics and AI
October 15, 2025 at 11:30 PM
Dr. Alireza Haghighi, my cofounder and I, are proud to announce an exciting partnership with Asia University to develop a "Sovereign AI Life Science Data Platform for Taiwan", a national system for secure health data sharing, AI-powered analytics, and collaborative research
October 15, 2025 at 11:30 PM
With ER-100 on track for human trials in Q1 2026, this program is moving quickly 💉👁️ Jerry McLaughlin, our CEO, and I are so grateful for the creativity, dedication, and persistence the board & entire R&D team led by Dr. Sharon Rosenzweig-Lipson
August 26, 2025 at 7:12 PM
This adds to earlier data showing clear functional benefits in the eye. They also beautifully match the mouse data we published in Nature (2020), in fact they are even more dramatic in their reversal of DNA methylation 😲 www.nature.com/articles/s41...
Reprogramming to recover youthful epigenetic information and restore vision - Nature
Expression of three Yamanaka transcription factors in mouse retinal ganglion cells restores youthful DNA methylation patterns, promotes axon regeneration after injury, and reverses vision loss in a mo...
www.nature.com
August 26, 2025 at 7:12 PM
These results add to the weight of evidence that reprogramming is not just for age-reversal, it can be used to treat diseases that affect millions worldwide and with few effective treatments
August 26, 2025 at 7:12 PM
In liver disease (MASH), ER-300, an AAV-delivered package of reprogramming genes, improved multiple key liver health biomarkers in an animal model, from ALT/AST to cholesterol and steatosis (fat content) scores
August 26, 2025 at 7:12 PM
Said presenter and CSO, Sharon Rosenzweig-Lipson, "These results bring us closer to pioneering a new class of epigenetic therapies that can modify the biology of aging itself and, in doing so, transform how age-related diseases, such as optic neuropathies and MASH, are addressed”
August 26, 2025 at 7:12 PM
Life Biosciences presented this new data
the ARDD conference in Copenhagen this week
August 26, 2025 at 7:12 PM
This news is strong evidence that the original vision to develop therapies that reversal of aging to prevent and cure diseases of aging and injuries isn’t just a fanciful idea
August 26, 2025 at 7:12 PM