davidavinson.bsky.social
@davidavinson.bsky.social
Reposted
Enjoyed writing this review on classic & emerging techniques being used to elucidate neuroepigenetic mechanisms using biochemistry, chemical and molecular biology in both in vitro/vivo models, with a focus on how these can drive therapeutic strategies in the near future.
www.cell.com/iscience/ful...
Elucidating neuroepigenetic mechanisms to inform targeted therapeutics for brain disorders
Therapeutics; Epigenetics; Neuroscience
www.cell.com
March 26, 2025 at 1:16 PM
Reposted
Excited to share the Maze Lab's (not on BlueSky yet) new publication, “Bidirectional histone monoaminylation dynamics regulate neural rhythmicity;” a massive collaboration (@davidlabmsk.bsky.social, Tom Muir, Simone Sidoli and Haitao Li) See 🧵 below for highlights www.nature.com/articles/s41...
Bidirectional histone monoaminylation dynamics regulate neural rhythmicity - Nature
TG2 functions as an eraser and exchanger of H3 monoaminylations, including histaminylation of Gln5 of histone H3.
www.nature.com
January 8, 2025 at 5:15 PM