8/11 Meanwhile, low-order sensory networks were barely affected by removing these feedback connections! Their responses remained strong, suggesting they rely mostly on local processing rather than whole-brain feedback.

7/11 The results were striking: high-order networks NEED feedback from the rest of the brain to generate their full response. When we cut these feedback connections, their responses were significantly reduced.

6/11 But why? To understand the mechanism, we built computational models of each patient's brain based on their anatomical connections, and then performed "virtual dissections" - selectively removing connections between networks.

5/11 We discovered an "excitability gradient" across the brain! High-order cognitive networks (like the Default Mode Network) showed much stronger responses to stimulation than low-order sensory networks.

1/11 How does our brain's hierarchical organization impact its response to stimulation? We found striking differences between "high-order" networks (involved in complex cognition) vs "low-order" networks (handling sensory/motor functions)
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www.nature.com/articles/s41...

My school in Tanzania is running well! The Giona Basketball Academy just hosted a U12–U19 tournament last week—so much fun! Want to join me in Tanzania, explore the country, and make an impact at my school? DM me! #FreeEducation #SportsValue #Basketball #Tanzania

🚀 @GiovanniRabuffo is presenting our poster "Large-Scale Neural Dynamics as a Predictor of Stimulus Effects" at the 6th #BrainStimConf!

📍 Poster P2.064

Don't miss it—come discuss our latest findings on neural dynamics and stimulation effects! #BrainStimulation #Neuroscience

Excited to attend Brain Stimulation Conference! Presenting 3 talks and chairing the symposium on Computational and Mathematical Models of Brain Stimulation-Induced Synaptic Plasticity. Looking forward to great discussions and connecting with this amazing community! #BrainStimConf

Truly honored and grateful that our symposium Advancements in Brain Stimulation Modeling has been accepted for #OHBM2025 marking our third time being part of this incredible event. Heartfelt thanks to the @ohbmofficial.bsky.social community for this opportunity! #BrainStimulation #modelling

🎉 Thrilled to announce that our course on Neural Field Theory & Brain Networks has been accepted for #OHBM2025! Third year teaching computational neuroscience at OHBM. Can't wait to explore brain dynamics in Brisbane!

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