Control of IRT1 cell surface levels is critical for plant iron uptake from the soil and was previously shown to be regulated by ubiquitin-mediated endocytosis upon non-iron metal excess. Here, we she...

The VIB-UGent Center for Plant Systems Biology (PSB) is a world-leading plant science institute located at the heart of a renowned Plant Biotech campus in Ghent, Belgium. Its mission is to integrate g...

Nature Reviews Molecular Cell Biology, Published online: 19 May 2025; doi:10.1038/s41580-025-00851-2The phytohormone auxin coordinates plant growth by forming local maxima and gradients through cell-to-cell transport and metabolic control. Recent research has identified novel signalling mechanisms involving extracellular auxin perception and auxin-mediated cyclic AMP production.

Epitope tags are broadly used for detecting, modifying or purifying proteins of interest, but their breadth of application is often rather poor. Recently, the rationally designed ALFA tag and its ALFA...