Thanks! And yes, depending on the reagent and pH, you will have some ion suppression and the sensitive will drop. To bypass that, I would run the initial runs without infusion/pH modulation.

Thanks so much to everybody who made this interdisciplinary project possible. And epically the editor and the three reviewers at @natcomms.nature.com for their throughout positive feedback.

Implementing the MCheM setup is pretty easy, and all reagents and hardware components are commercially available and relatively cheap.
MCheM data analysis is supported in @mzmine.bsky.social @gnps2.bsky.social and SIRIUS (@brightgiant.bsky.social) and free for academic researchers.

Thanks Gabriel :)

Thanks Don! Will post about the new work here and on our webpage www.functional-metabolomics.com/publication

Thanks a lot Tri :)

Thanks a lot Manuel!

www.grainger.com/product/SMC-...

I looked into it for a long time, happy to chat about details. I was close to buying one, but acilities finally increased the pressure to 110 psi. Was definitely worth the fight. Passive N2 generator works like a charm.

Big Congrats!!!