Hai Dang Nguyen, Ph.D
@danglab.bsky.social
Assistant Prof @UMN_GPP @UMNCancer. R-Loop, DNA damage response, RNA processing, functional genomics, entrepreneurship, biotech dance
Glad to be a part of this work with @uwmadisonrna.bsky.social
Happy to share our latest work, led by Sierra Love and in collaboration with Melissa Jurica's lab at UCSC and @danglab.bsky.social at U. Minnesota-Twin Cities. This work was funded by the Edward P. Evans Foundation/EvansMDS.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A Yeast-Based High-Throughput Screening Platform for the Discovery of Novel pre-mRNA Splicing Modulators
Pre-mRNA splicing is a crucial process in eukaryotic gene expression, and splicing dysregulation has been linked to various diseases. However, very few small molecules have been discovered that can mo...
www.biorxiv.org
October 21, 2025 at 10:07 PM
Glad to be a part of this work with @uwmadisonrna.bsky.social
Our paper is out in press on #Cancer #Research this week! A fun collaboration with Dr. Taylor’s lab at U. of Miami.
Potential targeted therapy for XPO1-mutant colorectal cancer.
Potential targeted therapy for XPO1-mutant colorectal cancer.
XPO1R749Q Mutations Co-occur with POLE Mutations in Cancer and can be Targeted to Overcome Chemoresistance
Abstract. XPO1 is a nuclear export receptor that is essential for cell survival. Previous genomic analyses have identified recurrent XPO1 hotspot mutations in cancer. Here, we conducted a large-scale ...
doi.org
June 19, 2025 at 1:47 PM
I maybe a bit bias but great lab to work with :-)
Where can I apply? 😜
Where can I apply? 😜
We are ready for #ASH2024! The Lee Lab @fredhutch.bsky.social has two presentations:
1-Elizabeth Bonner @ebonner.bsky.social will give a talk on SF3B1 mutations in MDS
2-Vivian Liu will present a poster on risk stratification in NPM1-mutant AML.
We’re also looking for a postdoc, so come meet us!
1-Elizabeth Bonner @ebonner.bsky.social will give a talk on SF3B1 mutations in MDS
2-Vivian Liu will present a poster on risk stratification in NPM1-mutant AML.
We’re also looking for a postdoc, so come meet us!
December 5, 2024 at 2:47 PM
I maybe a bit bias but great lab to work with :-)
Where can I apply? 😜
Where can I apply? 😜
Reposted by Hai Dang Nguyen, Ph.D
We just opened a search for a lab-based faculty position at Dana-Farber @danafarber.bsky.social @harvardmed.bsky.social
Any area of cancer research is fair game and MD, PhD, or MD/PhD are encouraged to apply.
Please spread the word:
www.nejmcareercenter.org/job/829239/l...
Any area of cancer research is fair game and MD, PhD, or MD/PhD are encouraged to apply.
Please spread the word:
www.nejmcareercenter.org/job/829239/l...
Laboratory-based Investigator, Faculty Search - Boston, Massachusetts job with Dana-Farber Cancer Institute | 829239
Laboratory-based Investigator, Faculty Search The Department of Medical Oncology at the Dana-Farber Cancer Institute (DFCI) and the Brigham and Wom...
www.nejmcareercenter.org
December 3, 2024 at 1:46 AM
We just opened a search for a lab-based faculty position at Dana-Farber @danafarber.bsky.social @harvardmed.bsky.social
Any area of cancer research is fair game and MD, PhD, or MD/PhD are encouraged to apply.
Please spread the word:
www.nejmcareercenter.org/job/829239/l...
Any area of cancer research is fair game and MD, PhD, or MD/PhD are encouraged to apply.
Please spread the word:
www.nejmcareercenter.org/job/829239/l...
Reposted by Hai Dang Nguyen, Ph.D
Another patient mutation in PARP-linked pathways is tied to neurological diseases. Excited to see how discoveries like the #ADPRS variant in CONDSIAS push us closer to unlocking new therapeutic pathways! 🧠🔬 #Neurodegeneration #ARH3 #ADP-ribosylation.
Congrats @danglab.bsky.social!
Congrats @danglab.bsky.social!
Excited to see our paper in press today at HGG Advances!!! We described a new variant in #ADPRS gene in individuals with CONDSIAS, disrupting its #ARH3 protein function leading to increased #ADP-ribosylation in cells.
bit.ly/3OmvwqH
bit.ly/3OmvwqH
November 25, 2024 at 7:44 PM
Another patient mutation in PARP-linked pathways is tied to neurological diseases. Excited to see how discoveries like the #ADPRS variant in CONDSIAS push us closer to unlocking new therapeutic pathways! 🧠🔬 #Neurodegeneration #ARH3 #ADP-ribosylation.
Congrats @danglab.bsky.social!
Congrats @danglab.bsky.social!
Excited to see our paper in press today at HGG Advances!!! We described a new variant in #ADPRS gene in individuals with CONDSIAS, disrupting its #ARH3 protein function leading to increased #ADP-ribosylation in cells.
bit.ly/3OmvwqH
bit.ly/3OmvwqH
November 25, 2024 at 7:11 PM
Excited to see our paper in press today at HGG Advances!!! We described a new variant in #ADPRS gene in individuals with CONDSIAS, disrupting its #ARH3 protein function leading to increased #ADP-ribosylation in cells.
bit.ly/3OmvwqH
bit.ly/3OmvwqH
Reposted by Hai Dang Nguyen, Ph.D
Join us to explore the fascinating world of PARPs that modify proteins, DNA, RNA, and beyond.
Dive into the latest discoveries on #DNArepair, #RNAbiology, #condensates, #drugdiscovery
Ping me to include you, and let’s reimagine our community together!
go.bsky.app/CiRKAXJ
Dive into the latest discoveries on #DNArepair, #RNAbiology, #condensates, #drugdiscovery
Ping me to include you, and let’s reimagine our community together!
go.bsky.app/CiRKAXJ
November 16, 2024 at 1:26 PM
Join us to explore the fascinating world of PARPs that modify proteins, DNA, RNA, and beyond.
Dive into the latest discoveries on #DNArepair, #RNAbiology, #condensates, #drugdiscovery
Ping me to include you, and let’s reimagine our community together!
go.bsky.app/CiRKAXJ
Dive into the latest discoveries on #DNArepair, #RNAbiology, #condensates, #drugdiscovery
Ping me to include you, and let’s reimagine our community together!
go.bsky.app/CiRKAXJ
Reposted by Hai Dang Nguyen, Ph.D
ok, I tried to make a starter pack on genome stability/DNA replication/DNA repair etc. Sorry if I couldn't find someone, please nominate yourself and your colleagues in comments or DMs, looking forward to connecting with everyone!
go.bsky.app/9jdDNxG
go.bsky.app/9jdDNxG
November 12, 2024 at 1:11 AM
ok, I tried to make a starter pack on genome stability/DNA replication/DNA repair etc. Sorry if I couldn't find someone, please nominate yourself and your colleagues in comments or DMs, looking forward to connecting with everyone!
go.bsky.app/9jdDNxG
go.bsky.app/9jdDNxG