Imad Damaj
damajlab.bsky.social
Imad Damaj
@damajlab.bsky.social
Neuropharmacology of pain and addiction
VCU
Just out in @TheJournal_Pain:

“Paclitaxel-Induced Neuroinflammation After Systemic Administration in Male and Female Mice”

Paclitaxel-induced increase in neuroinflammation is time-, sex-, and tissue- dependent.

www.jpain.org/article/S152...
Paclitaxel-Induced Neuroinflammation After Systemic Administration in Male and Female Mice
Peripheral neuropathy is one of the most prevalent neurotoxic, dose-limiting side effects of paclitaxel, a chemotherapy agent used widely in solid cancers. The mechanism of paclitaxel-induced peripher...
www.jpain.org
July 26, 2025 at 5:26 PM
Check out our newest paper with the talented former Ph.D. Student Bryan McKiver!

Astrocyte elevated gene-1 (AEG-1) in myeloid cells is a key driver for the development of chemotherapy-induced peripheral neuropathy.

www.sciencedirect.com/science/arti...
Astrocyte elevated gene-1 (AEG-1) in myeloid cells is a key driver for the development of chemotherapy-induced peripheral neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting side effect of chemotherapy treatment, often resulting in the discontinuation of …
www.sciencedirect.com
March 30, 2025 at 3:28 PM
Just out: Our paper in collaboration with Javier Gonzalez-Maeso group demonstrating the long lasting effects of a single dose of psilocybin in mouse models of chronic pain.
@jgmaeso.bsky.social

www.sciencedirect.com/science/arti...
IUPHAR Article: Psilocybin induces long-lasting effects via 5-HT2A receptors in mouse models of chronic pain
Chronic pain is a debilitating disease with current treatments lacking efficacy and safety, therefore discovery of new treatments is crucial. Initial …
www.sciencedirect.com
March 17, 2025 at 11:54 PM
Reposted by Imad Damaj
Research is investigating the medicinal applications of #psilocybin, with studies showing how #psychedelics can promote neuronal plasticity.

This ‘fundamental’ study into the effects of #psilocin on human neurons: buff.ly/f7cNemV
March 16, 2025 at 9:01 PM
I was happy to be part of this interesting study with @jgmaeso.bsky.social and his team!
“Upregulation of the neuropeptide receptor calcitonin receptor-like in the spinal cord via MLL2 in a mouse model of paclitaxel-induced peripheral neuropathy”

journals.sagepub.com/doi/10.1177/...
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February 22, 2025 at 9:37 PM
Join us for this interesting virtual conference!
January 31, 2025 at 11:15 AM