Angelo D’Alessandro
@dalessandrolab.bsky.social
Small molecules, big data and something (often red blood cells) in between…
Thank you, Thomas!
October 23, 2025 at 12:03 PM
Thank you, Thomas!
Congratulations!
September 5, 2025 at 1:54 AM
Congratulations!
As always, this is a team effort, led by Daniel Stephenson, Greg Keele @grkeele.bsky.social and Grier Page @rti.bsky.social, experts in ferroptosis @brentstockwell.bsky.social - blood storage and transfusion medicine - from the Zimring lab at UVA, Vitalant Research Institute, UCSF
August 14, 2025 at 6:17 PM
As always, this is a team effort, led by Daniel Stephenson, Greg Keele @grkeele.bsky.social and Grier Page @rti.bsky.social, experts in ferroptosis @brentstockwell.bsky.social - blood storage and transfusion medicine - from the Zimring lab at UVA, Vitalant Research Institute, UCSF
Really cool! Heme catabolism and biliverdin/bilirubin steps are NADPH dependent, and G6PD deficiency may protect from malaria. I wonder if/how the two stories line up
July 18, 2025 at 9:00 PM
Really cool! Heme catabolism and biliverdin/bilirubin steps are NADPH dependent, and G6PD deficiency may protect from malaria. I wonder if/how the two stories line up
Does it track with hemoglobin levels? HBB C93 and glutathione seem to track at a 1:1 ratio in humans and mice.
They used 13C 15N-glycine in vivo, it would be interesting to see how GSH synthesis rates track with de novo heme synthesis
They used 13C 15N-glycine in vivo, it would be interesting to see how GSH synthesis rates track with de novo heme synthesis
July 8, 2025 at 2:15 AM
Does it track with hemoglobin levels? HBB C93 and glutathione seem to track at a 1:1 ratio in humans and mice.
They used 13C 15N-glycine in vivo, it would be interesting to see how GSH synthesis rates track with de novo heme synthesis
They used 13C 15N-glycine in vivo, it would be interesting to see how GSH synthesis rates track with de novo heme synthesis
So nice to finally associate a face and person to the names and papers, especially when it turns out to be such a lovely company! Thank you for the evening!
June 14, 2025 at 12:10 AM
So nice to finally associate a face and person to the names and papers, especially when it turns out to be such a lovely company! Thank you for the evening!