Dadi Jiang, PhD
dadijiang.bsky.social
Dadi Jiang, PhD
@dadijiang.bsky.social
Reposted by Dadi Jiang, PhD
🎉 The #ARTNet roadmap article is now published in Nature Review Cancer.
Kudos to former Functional Screens & Assays WG chairs Drs. Alice Soragni @alice.soragnilab.com & Erik Knudsen, and all WG members for their valuable contributions! #ARTNetPublication
www.nature.com/articles/s41...
Acquired resistance in cancer: towards targeted therapeutic strategies - Nature Reviews Cancer
Acquired therapeutic resistance is a key contributor to cancer treatment failure, requiring new approaches to address its complex mechanisms. In this Roadmap, Soragni, Knudsen and colleagues discuss t...
www.nature.com
June 3, 2025 at 4:11 PM
This is a masterpiece from the @nciartnet.bsky.social on our current understanding and toolbox toward acquired resistance to cancer treatment.

www.nature.com/articles/s41...
Acquired resistance in cancer: towards targeted therapeutic strategies - Nature Reviews Cancer
Acquired therapeutic resistance is a key contributor to cancer treatment failure, requiring new approaches to address its complex mechanisms. In this Roadmap, Soragni, Knudsen and colleagues discuss t...
www.nature.com
June 3, 2025 at 4:33 PM
Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance: Cancer Cell www.cell.com/cancer-cell/...
Radiotherapy promotes cuproptosis and synergizes with cuproptosis inducers to overcome tumor radioresistance
Lei et al. reveal that radiotherapy (RT) elevates mitochondrial copper and induces cuproptosis by upregulating CTR1 and depleting mitochondrial glutathione. Furthermore, BACH1 downregulation confers r...
www.cell.com
April 10, 2025 at 8:47 PM
Reposted by Dadi Jiang, PhD
New research found that adding copper-loaded agents to radiotherapy increased intracellular copper levels and induced cuproptosis, overcoming radioresistance.

Why this approach has quick translational potential as a therapeutic strategy: brnw.ch/21wRUPU #EndCancer
Agents that cause ‘copper overload’ can overcome radiotherapy resistance in preclinical models
Agents that cause ‘copper overload’ can overcome radiotherapy resistance in preclinical models
brnw.ch
April 10, 2025 at 5:39 PM
Reposted by Dadi Jiang, PhD
Lab dinner to celebrate Ayeisha and Ariana’s acceptance to MSTP and cancer bio PhD program. So proud of these 2 superstars! #endcancer #radonc @mdanderson.bsky.social
March 8, 2025 at 4:06 AM