CoSy.Bio
@cosybio-uhh.bsky.social
Computational Systems Biomedicine research group at the University Hamburg
We present FedscGen, a federated, #PrivacyPreserving method (built on scGen) batch-effect correction tool to help analyze distributed #scRNAseq datasets.
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
October 6, 2025 at 11:56 AM
We present FedscGen, a federated, #PrivacyPreserving method (built on scGen) batch-effect correction tool to help analyze distributed #scRNAseq datasets.
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
✨ Congratulations to Faren, the winner of the Young Investigator Award #RExPO25! This is a truly well-deserved recognition of her outstanding research and impact. 👏 @repo4eu.bsky.social
September 29, 2025 at 10:21 AM
✨ Congratulations to Faren, the winner of the Young Investigator Award #RExPO25! This is a truly well-deserved recognition of her outstanding research and impact. 👏 @repo4eu.bsky.social
#Acne and other #SkinDisorders are often linked to the sebaceous gland (SG). We provide a detailed molecular map of the human SG, revealing dynamic differentiation of sebocytes and identifying new #GeneMarkers, providing a valuable reference for future research.
www.jidonline.org/article/S002...
www.jidonline.org/article/S002...
September 22, 2025 at 12:28 PM
#Acne and other #SkinDisorders are often linked to the sebaceous gland (SG). We provide a detailed molecular map of the human SG, revealing dynamic differentiation of sebocytes and identifying new #GeneMarkers, providing a valuable reference for future research.
www.jidonline.org/article/S002...
www.jidonline.org/article/S002...
🚀🦠 Exciting discussions at the @microb-ai-ome.bsky.social Steering Committee Meeting in Vienna! Great to see progress at the intersection of #MicrobiomeResearch and #AI!
September 15, 2025 at 11:24 AM
🚀🦠 Exciting discussions at the @microb-ai-ome.bsky.social Steering Committee Meeting in Vienna! Great to see progress at the intersection of #MicrobiomeResearch and #AI!
Studying #BoneTissue proteins can be likened to finding a needle in a haystack of collagen. Our new protocol eliminates collagen interference without the use of enzymes, yielding 68% more proteins identified. #proteomics
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
September 11, 2025 at 1:11 PM
Studying #BoneTissue proteins can be likened to finding a needle in a haystack of collagen. Our new protocol eliminates collagen interference without the use of enzymes, yielding 68% more proteins identified. #proteomics
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
We introduce DRaCOoN 🐉: a Python package and web tool designed for pathway-level #DifferentialCoexpression analysis. It features a unique benchmarking framework and demonstrates robust performance across various #Transcriptomics datasets.
bmcbioinformatics.biomedcentral.com/articles/10....
bmcbioinformatics.biomedcentral.com/articles/10....
September 8, 2025 at 9:54 AM
We introduce DRaCOoN 🐉: a Python package and web tool designed for pathway-level #DifferentialCoexpression analysis. It features a unique benchmarking framework and demonstrates robust performance across various #Transcriptomics datasets.
bmcbioinformatics.biomedcentral.com/articles/10....
bmcbioinformatics.biomedcentral.com/articles/10....
Presenting DIGGER 2.0: we extended our #AlternativeSplicing software DIGGER with new functionalities, including support of the mouse interactome and NEASE for #EnrichmentAnalysis! Check it out here: exbio.wzw.tum.de/digger/
August 21, 2025 at 11:32 AM
Presenting DIGGER 2.0: we extended our #AlternativeSplicing software DIGGER with new functionalities, including support of the mouse interactome and NEASE for #EnrichmentAnalysis! Check it out here: exbio.wzw.tum.de/digger/
When is "good enough" actually good enough for #PrognosticModels? Our commentary tackles this question with a structured analysis of 16 scenarios + practical approaches for development decisions for healthcare-related prognostic models.
www.jmir.org/2025/1/e69341
www.jmir.org/2025/1/e69341
August 7, 2025 at 9:01 AM
When is "good enough" actually good enough for #PrognosticModels? Our commentary tackles this question with a structured analysis of 16 scenarios + practical approaches for development decisions for healthcare-related prognostic models.
www.jmir.org/2025/1/e69341
www.jmir.org/2025/1/e69341
Defective interfering particles (DIPs) as potential novel #Antivirals! Our meta-analysis of 20 #Influenza datasets provides insights for selecting candidates for antiviral treatment design.
academic.oup.com/nargab/artic...
academic.oup.com/nargab/artic...
July 28, 2025 at 8:27 AM
Defective interfering particles (DIPs) as potential novel #Antivirals! Our meta-analysis of 20 #Influenza datasets provides insights for selecting candidates for antiviral treatment design.
academic.oup.com/nargab/artic...
academic.oup.com/nargab/artic...
We compared various models predicting changes in #KneePain of #Osteoarthritis patients due to participation in supervised education and exercise and propose a concise 6-variable model for personalized prediction.
rehab.jmir.org/2025/1/e60162
rehab.jmir.org/2025/1/e60162
July 21, 2025 at 7:46 AM
We compared various models predicting changes in #KneePain of #Osteoarthritis patients due to participation in supervised education and exercise and propose a concise 6-variable model for personalized prediction.
rehab.jmir.org/2025/1/e60162
rehab.jmir.org/2025/1/e60162
Introducing DREAMER, a groundbreaking tool that identifies mechanisms of #AdverseDrugReactions (ADRs) by linking drug and disease phenotypes to protein interaction networks. Here, DREAMER revealed #MolecularMechanisms behind 67 ADRs.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
June 30, 2025 at 11:46 AM
Introducing DREAMER, a groundbreaking tool that identifies mechanisms of #AdverseDrugReactions (ADRs) by linking drug and disease phenotypes to protein interaction networks. Here, DREAMER revealed #MolecularMechanisms behind 67 ADRs.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Join CoSy.Bio in Hamburg!
We are looking for a System Administrator to support our team.
🔧 Linux/macOS | HPC | Automation | Bioinformatics
📍 Hamburg
🗓️ Apply by June 27
🔗 www.stepstone.de/stellenangeb...
We are looking for a System Administrator to support our team.
🔧 Linux/macOS | HPC | Automation | Bioinformatics
📍 Hamburg
🗓️ Apply by June 27
🔗 www.stepstone.de/stellenangeb...
www.stepstone.de
June 23, 2025 at 11:11 AM
Join CoSy.Bio in Hamburg!
We are looking for a System Administrator to support our team.
🔧 Linux/macOS | HPC | Automation | Bioinformatics
📍 Hamburg
🗓️ Apply by June 27
🔗 www.stepstone.de/stellenangeb...
We are looking for a System Administrator to support our team.
🔧 Linux/macOS | HPC | Automation | Bioinformatics
📍 Hamburg
🗓️ Apply by June 27
🔗 www.stepstone.de/stellenangeb...
We wrapped up a productive @daibetes.bsky.social Steering Committee Meeting last week in Boston!
Great discussions on how privacy-preserving #AI can advance #DiabetesResearch and #PersonalizedPatientCare.
Great discussions on how privacy-preserving #AI can advance #DiabetesResearch and #PersonalizedPatientCare.
June 10, 2025 at 12:47 PM
We wrapped up a productive @daibetes.bsky.social Steering Committee Meeting last week in Boston!
Great discussions on how privacy-preserving #AI can advance #DiabetesResearch and #PersonalizedPatientCare.
Great discussions on how privacy-preserving #AI can advance #DiabetesResearch and #PersonalizedPatientCare.
Soluble guanylate cyclase (sGC) protects cells from #OxidativeStress. Our research shows ta cGMP-dependent reduction of #ReactiveOxygenSpecies (ROS) upon soluble guanylate cyclase activation via a downregulation of NOX4/5 via NF-κB. Our findings have significant implications for #StrokeRecovery!
June 2, 2025 at 12:16 PM
Soluble guanylate cyclase (sGC) protects cells from #OxidativeStress. Our research shows ta cGMP-dependent reduction of #ReactiveOxygenSpecies (ROS) upon soluble guanylate cyclase activation via a downregulation of NOX4/5 via NF-κB. Our findings have significant implications for #StrokeRecovery!
Watch the new video on dAIbetes! This @horizoneu.bsky.social project leverages #AI and #FederatedLearning to transform type 2 diabetes treatment. Discover how virtual twins and secure data sharing are enabling personalized care. #DigitalHealth #DiabetesResearch
daibetes.eu/news/details...
daibetes.eu/news/details...
dAIbetes video - dAIbetes
dAIbetes as a whole, just have a look at the ⇒ video
daibetes.eu
May 12, 2025 at 1:06 PM
Watch the new video on dAIbetes! This @horizoneu.bsky.social project leverages #AI and #FederatedLearning to transform type 2 diabetes treatment. Discover how virtual twins and secure data sharing are enabling personalized care. #DigitalHealth #DiabetesResearch
daibetes.eu/news/details...
daibetes.eu/news/details...
Say goodbye to endless PDF scrolling and hello to faster discoveries! 🌟💊 Check out how DrugRepoChatter is revolutionizing #DrugRepurposing research!
Experts from the #REPO4EU Consortium have joined forces to develop an AI tool that helps #DrugRepurposing researchers do literature review faster and more efficiently 💊 📝
Bioinformatician Fernando Delgado-Chaves from @cosybio-uhh.bsky.social explains how it works ⤵️
repo4.eu/2025/02/14/r...
Bioinformatician Fernando Delgado-Chaves from @cosybio-uhh.bsky.social explains how it works ⤵️
repo4.eu/2025/02/14/r...
March 10, 2025 at 1:28 PM
Say goodbye to endless PDF scrolling and hello to faster discoveries! 🌟💊 Check out how DrugRepoChatter is revolutionizing #DrugRepurposing research!
Are you ready to shape the future of #LifeSciences? Join us and be part of the revolution in #AI and #MachineLearning innovation! Apply now!
#PhD #postdoc
#PhD #postdoc
February 21, 2025 at 4:49 PM
Are you ready to shape the future of #LifeSciences? Join us and be part of the revolution in #AI and #MachineLearning innovation! Apply now!
#PhD #postdoc
#PhD #postdoc
🚨Join us in pioneering the future of #LifeSciences! Apply now to be at the forefront of #AI and #MachineLearning innovation!
February 14, 2025 at 2:18 PM
🚨Join us in pioneering the future of #LifeSciences! Apply now to be at the forefront of #AI and #MachineLearning innovation!
Meet BioChatter! CoSy.Bio contributed to this open source framework for interfacing with #LLMs in biomedical research while ensuring user safety and privacy. Explore BioChatter at www.nature.com/articles/s41...
@saezlab.bsky.social
@saezlab.bsky.social
A platform for the biomedical application of large language models - Nature Biotechnology
Nature Biotechnology - A platform for the biomedical application of large language models
www.nature.com
February 10, 2025 at 1:21 PM
Meet BioChatter! CoSy.Bio contributed to this open source framework for interfacing with #LLMs in biomedical research while ensuring user safety and privacy. Explore BioChatter at www.nature.com/articles/s41...
@saezlab.bsky.social
@saezlab.bsky.social
Predicting drug responses is crucial for #PersonalizedMedicine. Our study reveals that #TranscriptionFactor activity-based methods outperform others in this task . #MachineLearning
www.nature.com/articles/s41...
www.nature.com/articles/s41...
February 3, 2025 at 12:22 PM
Predicting drug responses is crucial for #PersonalizedMedicine. Our study reveals that #TranscriptionFactor activity-based methods outperform others in this task . #MachineLearning
www.nature.com/articles/s41...
www.nature.com/articles/s41...