Conway Group
@conway-group.bsky.social
Medicinal Chemistry & Chemical Biology research group. Stuart holds the Michael & Alice Jung Endowed Chair in Medicinal Chemistry & Drug Discovery @ UCLA (@uclacb.bsky.social).
Website: https://sites.google.com/view/conwaygroup
ORCiD: 0000-0002-5148-117X
Website: https://sites.google.com/view/conwaygroup
ORCiD: 0000-0002-5148-117X
As the active PROTAC is revealed selectively in hypoxia, POI (BRD4) degradation occurs mainly in hypoxia. This technology has the potential to give PROTACs that degrade selectively in hypoxic tumors.
This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.
This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.
June 21, 2025 at 3:32 PM
As the active PROTAC is revealed selectively in hypoxia, POI (BRD4) degradation occurs mainly in hypoxia. This technology has the potential to give PROTACs that degrade selectively in hypoxic tumors.
This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.
This is collaborative work with @hammond-lab.bsky.social - congratulations to all of the authors.
My kids were taught science by the granddaughter of Hans Krebs. When she rode her bike to work I was always amused by seeing the Krebs’ cycle.
April 11, 2025 at 12:37 AM
My kids were taught science by the granddaughter of Hans Krebs. When she rode her bike to work I was always amused by seeing the Krebs’ cycle.
Yes super disappointing.
March 12, 2025 at 1:58 PM
Yes super disappointing.