Julien Colombani & Ditte Andersen lab
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colombani-lab.bsky.social
Julien Colombani & Ditte Andersen lab
@colombani-lab.bsky.social
850 followers 240 following 19 posts
Drosophila geneticists at the Department of Biology, Copenhagen University. We study intestinal stem cell, inter-organ communication and cancer biology. #Drosophila
https://www1.bio.ku.dk/english/research/cell-neurobiology/andersen-colombani-lab/
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Reposted by Julien Colombani & Ditte Andersen lab
universitypost.bsky.social
Cuts to the Faculty of Science will lead to poorer education programmes, write student reps on the Study Board of Biology:
uniavisen.dk/en/the-stude...
The students are also affected by layoffs at the Faculty of Science
We fear cancelled courses and poorer quality of education, and we don't think the management acknowledges the gravity of the situation.
uniavisen.dk
November 17, 2025 at 1:29 PM
Reposted by Julien Colombani & Ditte Andersen lab
corderolab.bsky.social
Excited to share our collaborative PhD project with Adam Dobson (Adam.Dobson@glasgow.ac.uk) on interorgan signalling in the ageing gut. Please contact Adam If you are a highly motivated student wanted to work on a super exciting Fly project.
October 1, 2025 at 9:56 AM
colombani-lab.bsky.social
Excited to share our last paper describing how intestinal stem cell migration promotes gut regeneration!
www.nature.com/articles/s41...
Pvf1-Pvr-mediated crosstalk between trachea and gut guides intestinal stem cell migration to promote gut regeneration - Nature Communications
Adult stem cells often reside in specialized niches that they exit upon injury. Here they show that in Drosophila, after damage the gut-associated trachea produces the PDGF-VEGF-related ligand Pvf1, which acts as a guidance cue directing ISC migration toward injury sites.
www.nature.com
September 29, 2025 at 8:04 PM
colombani-lab.bsky.social
We are looking forward to seeing you at the @edrc2025.bsky.social
You can find us
- On Thursday 25th at the workshop: INTERORGAN COMMUNICATION IN THE ERA OF OMICS,
- On Saturday morning 27th @alphyjohn.bsky.social will give a talk in the session stem cells and regeneration
- On poster sessions
September 22, 2025 at 8:34 AM
Reposted by Julien Colombani & Ditte Andersen lab
corderolab.bsky.social
2 post-doc positions open in the lab to do research on inter-organ signalling in regeneration and cancer in flies and mice.
August 11, 2025 at 4:29 PM
Reposted by Julien Colombani & Ditte Andersen lab
corderolab.bsky.social
Very happy and proud to share the latest work from our lab.
Neuroendocrine control of intestinal regeneration through the vascular niche.
www.sciencedirect.com/science/arti...
Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila
Robust and controlled intestinal regeneration involves reciprocal interactions between the intestinal epithelium and its microenvironment. Here, we id…
www.sciencedirect.com
July 21, 2025 at 6:19 PM
colombani-lab.bsky.social
Great meeting!
May 16, 2025 at 10:41 AM
colombani-lab.bsky.social
Great works of @rustenlab.bsky.social and @Basler lab independently showing how premalignant cells can exploit Toll-NF-κB signaling, in concert with oncogenic Ras, to enable unchecked growth #Drosophila Papers: plos.io/4jqpmUh and plos.io/3RGWESS Primer: plos.io/3GyUeU0
April 30, 2025 at 8:19 AM
Reposted by Julien Colombani & Ditte Andersen lab
plosbiology.org
#InnateImmunity is a crucial surveillance framework. However, @colombani-lab.bsky.social explores 2 @plosbiology.org studies which show that pre-malignant cells can exploit these regulatory circuits to enable unchecked #cancer growth 🧪 Papers: plos.io/4jqpmUh plos.io/3RGWESS Primer: plos.io/3GyUeU0
Schematics Top: While Toll-NF-κB pathway activation alone inhibits differentiation, trapping cells in a progenitor-like state, it also increases cell death rates leading to an overall reduction in tissue size. Bottom: In the presence of oncogenic RasV12, these progenitor-like cells become refractory to cell death, which drives tumor growth. Additionally, NF-κB/Dorsal activates JNK signaling and enhances the invasiveness of polarity-deficient RasV12/scrib−/− tumors.
April 30, 2025 at 7:59 AM
Reposted by Julien Colombani & Ditte Andersen lab
corderolab.bsky.social
Happy to share the preprint of our latest work on gut/vascular interactions in flies and mice! www.biorxiv.org/cgi/content/...
Intestinal Tissue Mechanics Regulate Angiogenesis and Stem Cell Proliferation via Vascular Piezo
The vasculature is a prominent component of developmental and adult tissue microenvironments. How, tissue specific characteristics and environmental states influence vascular biology and function, rem...
www.biorxiv.org
April 17, 2025 at 11:39 AM
colombani-lab.bsky.social
Great lab! Great Xmas lunch!
December 17, 2024 at 5:25 PM
colombani-lab.bsky.social
December 13, 2024 at 3:38 PM
Reposted by Julien Colombani & Ditte Andersen lab
edrc2025.bsky.social
Welcome to the #EDRC2025 account of the 28th European Drosophila Conference which will take place in Alicante from the 25th to the 28th of September 2025! Stay tuned for the upcoming news!
November 20, 2024 at 5:18 PM
colombani-lab.bsky.social
Excited to share our last preprint describing how intestinal stem cell migration promotes gut regeneration!
www.biorxiv.org/content/10.1...
Pvf1-PvR-mediated crosstalk between the trachea and the gut guides intestinal stem cell migration to promote gut regeneration.
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
September 4, 2024 at 7:12 AM
colombani-lab.bsky.social
The small intestine adapt its size according to nutrient intake 👇👇
www1.bio.ku.dk/english/news...
The small intestine adapt its size according to nutrient intake
Resizing of the intestine is a highly conserved strategy employed by a wide range of organisms to cope with fluctuation in nutrient availability. Nevertheless, very little is known about the mechanism...
www1.bio.ku.dk
March 4, 2024 at 7:03 PM
colombani-lab.bsky.social
Exciting beginning of the year with the accepted version of our activins paper "Drosophila activins adapt gut size to food intake and promote regenerative growth"
rdcu.be/du9K2
January 4, 2024 at 4:49 PM
colombani-lab.bsky.social
Wishing everyone happy holidays! Thank you to the lab for creating a lovely environment!

Here is the latest photo of us celebrating at our recent Christmas lunch!
December 26, 2023 at 9:08 AM
Reposted by Julien Colombani & Ditte Andersen lab
helenweavers.bsky.social
Want to explore dynamic cell & tissue responses to damage?
Apply for our fully-funded #PhDposition @BristolBiochem unravelling molecular mechanisms of #tissuerepair & #inflammation using #liveimaging #omics #cellbiology and #Drosophila for 2024.

Please share! Apply here: shorturl.at/fLY26
December 21, 2023 at 10:16 AM
colombani-lab.bsky.social
Interesting visit of the medical museum with the relevant "mind the gut" exhibition! A bit of brainwashing for the kids...
November 19, 2023 at 2:34 PM