COLLABORATE Randomised Controlled Trial
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COLLABORATE Randomised Controlled Trial
@collaborate-rct.bsky.social
UK-wide, real-world-data-enabled, adaptive, 2-randomisation, controlled trial to determine clinical efficacy, effect size, and safety of widely used enteral feeds in reducing necrotising enterocolitis, mortality, and cognitive impairment in preterm babies
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Should pasteurised donor milk or preterm formula be used when a supplement for own mother's milk is needed, and is routine protein-carbohydrate fortification of human milk beneficial and safe?

Watch the COLLABORATE explainer video below. youtu.be/hQ3zq08BbRk
COLLABORATE Parent Explainer Animation Video
YouTube video by COLLABORATE Randomised Controlled Trial
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Reposted by COLLABORATE Randomised Controlled Trial
Honoured to be part of the excellent Middlesbrough neonatal meeting 2025 at James Cook University Hospital! Great science, great friendship, great hospitality! Pleased to discuss the COLLABORATE study www.imperial.ac.uk/neonatal-dat... 🙏🏽🙏🏽🙏🏽 @cardioneo.bsky.social @calumtheroberts.bsky.social
June 6, 2025 at 6:25 PM
Should pasteurised donor milk or preterm formula be used when a supplement for own mother's milk is needed, and is routine protein-carbohydrate fortification of human milk beneficial and safe?

Watch the COLLABORATE explainer video below. youtu.be/hQ3zq08BbRk
COLLABORATE Parent Explainer Animation Video
YouTube video by COLLABORATE Randomised Controlled Trial
youtu.be
May 6, 2025 at 10:54 AM
To download the COLLABORATE Flyers for your use, kindly follow this link : www.imperial.ac.uk/neonatal-dat...
April 25, 2025 at 10:37 AM
Reposted by COLLABORATE Randomised Controlled Trial
Delighted to link up @neonatalsurgery.bsky.social @fionamet.bsky.social & we’d love to discuss @collaborate-rct.bsky.social with you; a 2-randomisation adaptive RCT to reduce severe NEC & improve cognitive outcomes for extremely preterm babies www.imperial.ac.uk/neonatal-dat...
April 22, 2025 at 7:49 PM
#COLLABORATErct is focused on improving newborn care together
🙏🏽🙏🏿🙏🏻🙏 to our inspirational delegates from across the 🌍 & many disciplines at Perinatal Science International 2025 all focused on strengthening research to improve care & policies for mothers & babies! @europerinatal.bsky.social @imperialcollegeldn.bsky.social
April 25, 2025 at 10:22 AM
The COLLABORATE Trial is funded by NIHR @imperialbrc.bsky.social

Watch the video below for more details:

youtu.be/pOjKbs1neHY
COLLABORATE Explainer Video
YouTube video by COLLABORATE Randomised Controlled Trial
youtu.be
April 25, 2025 at 10:20 AM
Reposted by COLLABORATE Randomised Controlled Trial
Calling all neonatal teams to help finally resolve longstanding uncertainties re formula, fortifier, pasteurised donor milk & NEC. Join #COLLABORATE_rct @99nicu.bsky.social @europerinatal.bsky.social @nihr.bsky.social
SIGNEC2025 London May 22-23 for latest in field & to hear about #COLLABORATE_rct a landmark adaptive, real-world data RCT to resolve uncertainties re NEC, formula, fortifier & pasteurised donor milk @bapmofficial.bsky.social @neonatalnursesuk.bsky.social @ebneo.bsky.social @necsociety.bsky.social
March 26, 2025 at 1:34 PM
Kindly watch the COLLABORATE Explainer video below youtu.be/5uGskrmVqvY
COLLABORATE Explainer Video
YouTube video by COLLABORATE Randomised Controlled Trial
youtu.be
April 8, 2025 at 1:21 PM
The COLLABORATE webinar series resume on April 14th.

More information here: lnkd.in/ed_EQhEP
April 8, 2025 at 11:58 AM
Join Session 2 of our webinar series today from 12.00-13.00 with @jamespboardman.bsky.social

Follow this link to join teams.microsoft.com/l/meetup-joi...
Join conversation
teams.microsoft.com
February 21, 2025 at 11:26 AM
Reposted by COLLABORATE Randomised Controlled Trial
Calling all UK neonatal teams! COLLABORATE, an adaptive, 2-randomisation, real-world-data-enabled RCT to reduce NEC will go live 06/25! We are running a series of webinars to explain & discuss the study Join us! All welcome! Web-links at www.imperial.ac.uk/neonatal-dat... @bapmofficial.bsky.social
COLLABORATE | Faculty of Medicine | Imperial College London
www.imperial.ac.uk
February 18, 2025 at 10:46 AM
We invite you to join one of our upcoming COLLABORATE webinars where the investigators will explain the study and provide opportunity for discussion. Open to everyone

Session 1: 19th February, 12.00-13.00,

Click through this link to join lnkd.in/ee543ArM

Find more here : lnkd.in/ed_EQhEP
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February 18, 2025 at 10:53 AM
We are looking for parents of preterm babies who have lived experience of Necrotising Enterocolitis

Kindly email us at COLLABORATE@imperial.ac.uk
February 18, 2025 at 10:51 AM
Reposted by COLLABORATE Randomised Controlled Trial
Is routine fortification of human milk feeds needed for very preterm babies? No RCT has shown neurodevelopmental benefit and 1 has shown harm. That’s why we’re doing @collaborate-rct.bsky.social www.imperial.ac.uk/neonatal-dat...; join us! @bapmofficial.bsky.social @neonatalnursesuk.bsky.social
January 26, 2025 at 5:04 AM
Reposted by COLLABORATE Randomised Controlled Trial
Randomisation 1 will determine if pasteurised human donor milk or preterm formula affect NEC and other outcomes if a supplement for own mother’s milk is required.

Randomisation 2 will determine if routine macronutrient fortification of human milk is beneficial.

2/2
December 17, 2024 at 7:04 PM
Reposted by COLLABORATE Randomised Controlled Trial
New RCT coming to the UK in 2025!

COLLABORATE will determine clinical efficacy, effect size, and safety of widely used enteral feeds in reducing surgical NEC, mortality, and cognitive impairment in extremely preterm babies.

2 randomisations:

1/2
December 17, 2024 at 7:04 PM
We welcome opportunity to support colleagues to deliver the #COLLABORATErct 2-randomisation controlled trial addressing the effects of pasteurised human donor milk, preterm formula, and cow-milk-derived fortifier on necrotising enterocolitis and other outcomes, in their countries.
January 14, 2025 at 10:04 AM
COLLABORATE is an efficient, real-world-data-enabled, adaptive, 2-randomisation trial of efficacy, effect size & safety of pasteurised donor milk, cow-milk fortifier & formula in reducing NEC. Summary, explainer video & fliers here: www.imperial.ac.uk/neonatal-dat...
COLLABORATE | Faculty of Medicine | Imperial College London
www.imperial.ac.uk
January 11, 2025 at 8:53 AM
COLLABORATE coming this year, will determine effects of donor milk, bovine fortifier & formula on surgical NEC, survival & cognition, key questions for all preterm babies. If interested in being a global partner email COLLABORATE@imperial.ac.uk
January 7, 2025 at 10:33 AM
COLLABORATE Powerpoint Summary of Trial Justification and Design view.officeapps.live.com/op/view.aspx...
view.officeapps.live.com
December 17, 2024 at 4:53 PM
Watch this short explainer below: youtu.be/7N1s4kbs0HQ?...
COLLABORATE Explainer Video
YouTube video by COLLABORATE Randomised Controlled Trial
youtu.be
December 17, 2024 at 4:52 PM