Coffee Cancer Guy
coffeecancerguy.bsky.social
Coffee Cancer Guy
@coffeecancerguy.bsky.social
Physician interested in Coffee, Oncology, Hematology, Medicine, Memes, and also Coffee.
Reposted by Coffee Cancer Guy
Congratulations to the Irish #TILLIRI investigators, led by Dr Denis O'Keefe! In a large observational study incl. people with lower limb injury & immobilization, VTE occurrence at 90 days was low.
#medsky #hemesky #INViTEresearch @jthjournal.bsky.social www.sciencedirect.com/science/arti...
The (T) thrombosis (I) in patients with (L) lower (L) limb (I) injuries (R) requiring (I) immobilisation (TILLIRI) Study
Patients requiring lower limb immobilisation after injury have an increased venous thromboembolism (VTE) risk. The extent of this risk in published st…
www.sciencedirect.com
December 2, 2024 at 10:52 AM
Reposted by Coffee Cancer Guy
Very nice overview of the current state of affairs in cardiogenic shock (published this week in @TheLancet):
November 17, 2024 at 2:27 AM
Reposted by Coffee Cancer Guy
Honey, stop what you're doing, new hyponatremia research just dropped!

What's it say?

It looks like slow correction is associated with worse outcomes, like death and length of stay!

Was it just a small study?

No, it was a meta-analysis of almost 12,000 patients!

jamanetwork.com/journals/jam...
Correction Rates and Clinical Outcomes in Hospitalized Adults With Severe Hyponatremia
This systematic review and meta-analysis evaluates the association of sodium correction rates with mortality among hospitalized adults with severe hyponatremia.
jamanetwork.com
November 19, 2024 at 4:51 AM
Reposted by Coffee Cancer Guy
Skytorial: Five pearls on olanzapine 😁

Between agitation and nausea/vomiting, olanzapine has a wide range of use.

Olanzapine is generally not a front-line agent (e.g., haloperidol or ondansetron often are). But sometimes, it really comes in clutch....
a man in a plaid shirt sits at a picnic table with the words " settle down " on the bottom
ALT: a man in a plaid shirt sits at a picnic table with the words " settle down " on the bottom
media.tenor.com
November 27, 2024 at 1:17 PM
Reposted by Coffee Cancer Guy
Tirzepatide significantly reduced cardiovascular risks and improved health status in obese heart failure patients compared to placebo.

by Packer M, Zile MR (...) Borlaug BA et 10 al. in N Engl J Med
Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity | NEJM
Obesity increases the risk of heart failure with preserved ejection fraction. Tirzepatide, a long-acting agonist of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor...
www.nejm.org
November 25, 2024 at 7:54 PM
Reposted by Coffee Cancer Guy
ICU Hemodynamics:

There is a lot of discussion about the role of methylene blue (MB) in refractory #septicshock. We don't have many RCTs in this topic & I read every new one with interest. This small RCT was recently published:
November 22, 2024 at 4:18 PM
Reposted by Coffee Cancer Guy
Study in #JAMAOnc from Scotland/Wales of nearly 50k #breastcancer patients suggests vaginal estrogen use *NOT* associated w increase risk of breast cancer-specific mortality.

More reassuring data 👍

jamanetwork.com/journals/jam...
Vaginal Estrogen Therapy Use and Survival in Breast Cancer
This cohort study compares the mortality risk associated with vaginal estrogen therapy vs no hormone replacement therapy in 2 cohorts of patients with breast cancer in Scotland and Wales.
jamanetwork.com
November 23, 2024 at 2:28 PM