CPCB
LightNews LightNews
banner
cmupittcompbio.bsky.social
CPCB
@cmupittcompbio.bsky.social
92 followers 41 following 10 posts
Official account for the Joint Carnegie Mellon and University of Pittsburgh Computational Biology Program
Posts Replies Media Videos
Reposted by CPCB
stevenwsmeal.bsky.social
I'm proud that this work is published and thankful for the excellent computational biology program I am a part of @csbpitt.bsky.social and @cmupittcompbio.bsky.social!
robineclee.bsky.social robineclee.bsky.social @robineclee.bsky.social · Aug 13
In @natcomms.nature.com, we used robot-controlled cytokine pulses and imaging single receptor complexes and TF dynamics reveal that repeat, dose-conserving stimulation prolongs NEMO/IKK activation and shifts NF-κB dynamics via chromatin remodeling, enabling accurate single-cell models rdcu.be/ezTxF
Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics
Nature Communications - Cells rely on limited numbers of transmembrane receptors to process signals from dynamic microenvironments. Using microfluidics and endogenous reporters, the authors track...
rdcu.be
August 15, 2025 at 1:46 PM
Reposted by CPCB
thebiozone.bsky.social
bioZone isn't just the name of your favorite educational youTube channel, its also an important strategy for geologists

watch on YouTube to support us 👇
youtube.com/shorts/lBfg6...
August 10, 2025 at 1:05 PM
Reposted by CPCB
robineclee.bsky.social
Thrilled to see our latest work online in Nature Communications rdcu.be/ezTxF! Congratulations and thanks to
@cmupittcompbio.bsky.social
PhD student Steven Smeal and all the co-authors for their critical contributions.
Time-varying stimuli that prolong IKK activation promote nuclear remodeling and mechanistic switching of NF-κB dynamics
Nature Communications - Cells rely on limited numbers of transmembrane receptors to process signals from dynamic microenvironments. Using microfluidics and endogenous reporters, the authors track...
rdcu.be
August 8, 2025 at 2:50 PM
Reposted by CPCB
csbpitt.bsky.social
New publication alert! 🧬 A team of Pitt computational biologists and virologists built a detailed model of how Eastern equine encephalitis virus rapidly hijacks host cells to replicate. Check it out in PLOS Computational Biology.

🔗 tinyurl.com/EasternEquine

#virology #computationalbiology
A detailed kinetic model of Eastern equine encephalitis virus replication in a susceptible host cell
Author summary Eastern equine encephalitis virus (EEEV) is a positive-sense RNA virus transmitted via mosquitoes. It can cause lethal disease in humans with a high mortality rate, exceeding 30%. There...
tinyurl.com
June 11, 2025 at 3:13 PM
cmupittcompbio.bsky.social
Congrats to all our 2025 CPCB grads! 🎓
csbpitt.bsky.social Computational & Systems Biology Dept. at Pitt @csbpitt.bsky.social · May 19
Congratulations to our graduates who attended the School of Medicine Class of 2025 Graduation yesterday! 🎓 💛
David Koes, BaDoi Phan, Andrew McNutt, Tyler Lovelace, Takis Benos, Haiyi Mao and Minxue Jia
May 19, 2025 at 9:48 PM
Reposted by CPCB
dkoes.compstruct.org
Was proud and honored to hood Dr. Drew McNutt at the Pitt School of Medicine Diploma Ceremony. Here we are rocking both the blue and gold and tartan colors representing our joint Pitt-CMU CompBio PhD program. Congratulations to Drew and the other @cmupittcompbio.bsky.social graduates!
May 19, 2025 at 1:55 PM
Reposted by CPCB
robineclee.bsky.social
When a bovine cytokine talks to a human cell: Lessons from cross-species signaling experiments. 😊 🐱 🐰 🐁 🐀 🐄
www.biorxiv.org/content/10.1...
April 22, 2025 at 9:07 PM
cmupittcompbio.bsky.social
Happy Pi Day from CPCB! We can't have our pie and eat it too, but we'll always have pi 🟡🥧❤️
March 14, 2025 at 7:49 PM
cmupittcompbio.bsky.social
Congratulations to Dr. Drew McNutt who last month successfully defended his thesis, Efficiency through Abstraction: Representation Learning for Cost-Effective Drug Discovery! Drew next plans to hike the Appalachian Trail -Can't wait to hear about this next exciting achievement! 🧪🧑‍💻➡️🥾🏕️
February 5, 2025 at 1:29 AM
cmupittcompbio.bsky.social
Celebrating our Fall 2024 grads as we roll into 2025 🥳
Congrats to all our newest alumni! Can't what to see what you do next 🧪🎓
January 21, 2025 at 10:10 PM
Reposted by CPCB
csbpitt.bsky.social
When Ali Tugrul Balci moved from Istanbul to Pittsburgh, he didn’t expect to find a second home. But through his PhD program, he discovered both a supportive community and a passion for #computationalbiology research. Read more in our graduate spotlight story: tinyurl.com/AliTugrulBalci
Graduate Spotlight: Ali Tugrul Balci, PhD '24
January 16, 2025 at 3:46 PM
Reposted by CPCB
thebiozone.bsky.social
What makes a queen bee a queen? 🐝🧬

shout out to @maliqa.bsky.social for narrating her first bioZone video!

watch on YouTube to support us 👇
youtube.com/shorts/0X8Iq...
January 12, 2025 at 2:59 PM
Reposted by CPCB
csbpitt.bsky.social
Congratulations to Joint CMU-Pitt PhD Program in Computational Biology student Achyudhan Kutuva, who received an award to attend the 2025 Systems Approaches to Cancer Biology (SACB) Conference in February. Good luck!
Achyudhan Kutuva, Joint CMU-Pitt PhD Program in Computational Biology student
January 6, 2025 at 3:45 PM
Reposted by CPCB
csbpitt.bsky.social
Congratulations to PhD candidate Sophia Hu, who recently delivered a talk at the International Conference on Systems Biology in Bombay, India. This was Hu’s first experience at an international conference, but she left feeling excited for the future of the field. 🔗Read more: tinyurl.com/SophiaHu
January 2, 2025 at 6:06 PM
cmupittcompbio.bsky.social
Last week several of our students presented their research at NeurIPS 2024 in Vancouver. We are so proud of the excellent work that they've accomplished and shared with the scientific community! 🧪
Check out each of their papers below:
December 19, 2024 at 6:51 PM
cmupittcompbio.bsky.social
Some of our faculty and students met up in Vancouver for @neuripsconf.bsky.social this past week to share and learn the latest in ML research - CPCB student poster pictures coming soon 👀
December 16, 2024 at 5:13 AM
Reposted by CPCB
ian-dunn.bsky.social
I'm presenting a new paper "Exploring Discrete Flow Matching for 3D De Novo Molecule Generation" at @workshopmlsb.bsky.social this week! More info in this thread but reach out if want to chat at NeurIPS about generative models or molecular design. arxiv.org/abs/2411.16644
December 11, 2024 at 9:21 PM
cmupittcompbio.bsky.social
We love to see a student-led collaboration 🧪👩‍💻
Look out for this work at @workshopmlsb.bsky.social!
dkoes.compstruct.org David Ryan Koes @dkoes.compstruct.org · Nov 26
We're looking forward to presenting this @workshopmlsb.bsky.social . This work was conceived and led by a group CPCB (@cmupittcompbio.bsky.social) students and learns a co-embedding of proteins and ligands to support ultra fast virtual screening. arxiv.org/pdf/2411.15418
Dimensionality reduced embedding space showing that ligand and their targets colocate and genomes self organize. SPRINT Enables Interpretable and Ultra-Fast Virtual Screening against Thousands of Proteomes Andrew T. McNutt ∗ University of Pittsburgh anm329@pitt.edu Abhinav K. Adduri∗ CMU, Arc Institute abhinav.adduri@arcinstitute.org Caleb N. Ellington∗ Carnegie Mellon University cellingt@cs.cmu.edu Monica T. Dayao Carnegie Mellon University mdayao@cs.cmu.edu Eric P. Xing CMU, MBZUAI, Petuum Inc. epxing@cs.cmu.edu Hosein Mohimani Carnegie Mellon University hoseinm@cs.cmu.edu David R. Koes University of Pittsburgh dkoes@pitt.edu
November 27, 2024 at 4:26 PM