Chris Bellas
@cmbellas.bsky.social
Environmental virology, metagenomics, pangenomes, endogenous viruses in protists, Polinton-like viruses. University of Innsbruck
Reposted by Chris Bellas
Can a phage defence system interfere with antibiotic action? 💊 Yes, it can! CBASS is triggered by antifolates and turns these mostly bacteriostatic drugs into bactericidal ones in bugs like V. cholerae. 🦠 www.nature.com/articles/s41564-023-01556-y Read full here: rdcu.be/du20r
The Vibrio cholerae CBASS phage defence system modulates resistance and killing by antifolate antibi...
High-throughput growth assays show that cyclic-oligonucleotide-based anti-phage signalling systems modulate Vibrio cholerae sensitivity to antifolates, and ultimately trigger cell lysis by these drugs...
www.nature.com
January 3, 2024 at 11:17 AM
Can a phage defence system interfere with antibiotic action? 💊 Yes, it can! CBASS is triggered by antifolates and turns these mostly bacteriostatic drugs into bactericidal ones in bugs like V. cholerae. 🦠 www.nature.com/articles/s41564-023-01556-y Read full here: rdcu.be/du20r