Nicola Cloete Foster
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cltnic004.bsky.social
Nicola Cloete Foster
@cltnic004.bsky.social
Statistical epidemiologist @lshtm, @ucl & @equicalcs with a focus on tuberculosis, chronic respiratory diseases and equitable distribution of health 🌍
Reposted by Nicola Cloete Foster
FSID is hiring a geospatial data scientist. Come join our fun team! fsid.co/careers/gds/
FSID
fsid.co
May 15, 2025 at 4:16 PM
Reposted by Nicola Cloete Foster
The impact of the PEPFAR funding freeze on HIV deaths and infections: a mathematical modelling study of seven countries in sub-Saharan Africa

The sudden cessation of #PEPFAR funding likely results in tens of thousands of #HIV deaths and new infections

www.thelancet.com/journals/ecl...
#MedSky
April 28, 2025 at 10:47 AM
Reposted by Nicola Cloete Foster
The 3rd edition of Health Inequality has kept aspects of the older two editions that @zetkin.bsky.social originally wrote & so many found to be an accessible way into understanding the complexities of health inequalities, but there are new bits too

Here's a wee thread to explain what we've done 😉
November 17, 2024 at 6:49 PM
Reposted by Nicola Cloete Foster
New pre-print modelling impact of US funding cuts on HIV, #TB, MCH and family planning. We estimate impact of termination of US funding to NTPs via #USAID & The Global Fund may lead to 2.2 (1.5-2.9) million excess TB deaths between 2025 and 2040, reversing over a decade of progress.

bit.ly/4lowp18
April 9, 2025 at 8:32 AM
Reposted by Nicola Cloete Foster
It's #WorldTBDay, so if you want to learn more about working in #tuberculosis research, we have just the podcast for you!

Last year on our Trial Talk podcast, we interviewed #TB #ClinicalTrials legends Andrew Nunn and Sarah Meredith about their accomplished careers. Tune in 👇
Careers in TB trials with Andrew Nunn and Sarah Meredith
In the first episode of our new Trial Talk series, Hanif Esmail and Conor Tweed take over the microphones to interview Andrew Nunn and Sarah Meredith, who have both recently retired from the Unit, hav
buff.ly
March 24, 2025 at 12:00 PM
Reposted by Nicola Cloete Foster
Today is #WorldTBDay.

#Tuberculosis - or TB - is caused by bacteria Mycobacterium tuberculosis that mainly affects the lungs.

Common symptoms include
❗️ Cough
❗️ Chest pains
❗️ Weight loss
❗️ Fever
❗️ Night sweats

Learn more about TB 👉 bit.ly/3yYNwzx #EndTB
March 24, 2025 at 1:53 AM
Reposted by Nicola Cloete Foster
Tuberculosis once affected almost everyone, but now it “travels the paths of injustice that we blazed for it,” says author @johngreensbluesky.bsky.social. He joins us to discuss his new book.
The Many, Many Ways Tuberculosis Shaped Human Life
In a new book, author John Green traces how the disease has impacted culture, geography, and even fashion over the centuries.
www.sciencefriday.com
March 21, 2025 at 6:21 PM
Reposted by Nicola Cloete Foster
This 😭
via @economist.com
March 17, 2025 at 9:12 AM
Reposted by Nicola Cloete Foster
The estimands framework encourages #ClinicalTrials researchers to precisely define their research question, reducing ambiguity when interpreting the results.

This paper explores the application of the estimands framework to trials in #IBD #InflammatoryBowelDisease. 👇
Applying the estimand framework to inflammatory bowel disease clinical trials
We aim to provide a primer to the estimand framework and to raise awareness of this concept as it is increasingly applied to IBD clinical trials.
buff.ly
March 6, 2025 at 12:00 PM
Reposted by Nicola Cloete Foster
New research

Immunogenicity, safety, and efficacy of the vaccine H56:IC31 in reducing the rate of tuberculosis recurrence in HIV-negative adults successfully treated for pulmonary tuberculosis: a double-blind, randomised, placebo-controlled, phase 2b trial

www.thelancet.com/journals/lan...
Immunogenicity, safety, and efficacy of the vaccine H56:IC31 in reducing the rate of tuberculosis disease recurrence in HIV-negative adults successfully treated for drug-susceptible pulmonary tubercul...
Vaccination with H56:IC31 at treatment completion for pulmonary tuberculosis did not reduce the risk of recurrent disease. H56:IC31 was well tolerated and immunogenic but might have increased the risk...
www.thelancet.com
March 6, 2025 at 9:43 AM
Sometimes working in science is tough (public health is in a bad space at this point in time), but the joy of finding things out and generating new knowledge - makes up for it www.bbc.co.uk/iplayer/epis...
Horizon - 1981-1982: The Pleasure of Finding Things Out
Professor Richard Feynman of Caltech talks about his life and career.
www.bbc.co.uk
March 2, 2025 at 3:00 PM
Reposted by Nicola Cloete Foster
Do you work in #ClinicalTrials? Using the estimands framework can ensure your study answers the most relevant research question.

In this podcast episode, @brennankahan.bsky.social discusses his work on estimands.

🎧Listen to short clip below & tune in to the episode👉 https://buff.ly/3PtETFq
January 31, 2025 at 2:03 PM
Reposted by Nicola Cloete Foster
⭐Tomorrow, Vanessa Didelez will present "Statistical Methods for Causal Inference with Time-to-Event Data in Epidemiology" at @bemcolloquium.bsky.social!

🗓️ Wed. Jan. 8
🕔 16:00 Berlin time (CET)
📍 Zoom webinar

Abstract + webinar sign up link: bemcolloquium.com/meetings-cal...

#EpiSky #CausalSky
BEMC Talks
BEMC Talks are generally held on the first Wednesday of each month at 4pm Berlin time (GMT+01:00) with some adjustments for holidays. An hour-long lecture will be followed by an interactive group d…
bemcolloquium.com
January 7, 2025 at 4:04 PM
Stayed up to watch the predicted snowfall ❄️. And was not disappointed - views of silent snowy trees and gardens outside. ☃️ London is magical when it snows. Hope the snow will still be there in the morning 🤞🏼
January 5, 2025 at 12:16 AM
Reposted by Nicola Cloete Foster
Love this poster! #medsky
December 18, 2024 at 8:11 AM
Reposted by Nicola Cloete Foster
All I want for Christmas is to know whether eating carrots lead to poor reindeer performance... (and time to post-prandial reindeer laziness) 🤶 Commentary by @suziecro.bsky.social & Rachel Phillips
trialsjournal.biomedcentral.com/articles/10....
All I want for Christmas…is a precisely defined research question - Trials
trialsjournal.biomedcentral.com
December 14, 2024 at 12:23 PM
Useful thread on challenges in implementing reproducible data analysis work flows 👇
Hello everyone! I teach a class for graduate students on methods for reproducible research. 🔧 🔢

I would interested to hear about the barriers you face in implementing reproducible practices in your research (e.g., version control, code review, reproducible documents).
December 10, 2024 at 8:40 AM
Reposted by Nicola Cloete Foster
Reposted by Nicola Cloete Foster
The {marginaleffects} package is an EXTREMELY useful tool for R & Python users that revolutionises the interpretation of models with complicated non-linear features.

Be sure to check out this introduction from @vincentab.bsky.social, @noahgreifer.bsky.social. and @andrew.heiss.phd!

#EpiSky
Our JSS article is out!

And now I get to focus on {marginaleffects} 1.0.0. Stay tuned.

www.jstatsoft.org/article/view...
December 2, 2024 at 12:19 AM
Highly recommended to follow this course, even if only able to do so online. I have found both the YouTube videos and textbook very useful.
I am running my statistical rethinking course again starting in January. But this time just for Leipzig locals, so I can work with a smaller group this year and track individual progress better. I think that will help me tune the material, espeically homework, better. Materials still open however.
GitHub - rmcelreath/stat_rethinking_2025
Contribute to rmcelreath/stat_rethinking_2025 development by creating an account on GitHub.
github.com
November 30, 2024 at 1:03 PM
Reposted by Nicola Cloete Foster
As I wrote about in worksinprogress.co/issue/why-we..., putting together funding, recruiting staff, setting up operations, etc. meant a 4 year delay before starting a pilot roll-out study of malaria vaccines. This stuff really matters
November 21, 2024 at 10:09 PM
Reposted by Nicola Cloete Foster
Very important finding from Joowhan Sung and Emily Kendall, presented at the Asymptomatic TB session at the #TBUnion conference last week!
2/
Implications of a trace Xpert Ultra (Joowhan Sung)
- 129 pts with trace Ultra were thoroughly investigated at baseline + followed up for 2 yrs
- ½ of pts diagnosed w/ prevalent or incident TB
- Incident TB strongly associated w/ abnormal CXR but NOT symptoms - supports symptom-agnostic testing
November 19, 2024 at 7:52 PM
Reposted by Nicola Cloete Foster
"Why doesn't the NHS use its GP data?". Because of privacy... Because it's hard... But we solved it. We developed new privacy protections... We built docs.OpenSAFELY.org! 181 projects! 31 organisations! Now, they come together, for the first time, in 3D!

www.bennett.ox.ac.uk/blog/2024/10...
OpenSAFELY Symposium 2024: there's still time to sign up | Bennett Institute for Applied Data Science
It’s not too late to register for our 2nd Annual OpenSAFELY Symposium, which is happening in London on 25/26 November.
www.bennett.ox.ac.uk
November 19, 2024 at 9:40 AM
As always, #UnionConf2024 was fantastic. This year, I especially enjoyed the TBScience sessions, focus on pharmacology and discussions with catching up with colleagues. Bali was magnificent 🏖️
November 16, 2024 at 7:47 AM