Join us next Friday 11:30 for Pietro's Sormanni seminar at @cienciasulisboa.bsky.social |
ciencias.ulisboa.pt/en/node/17783

📣 In Alzheimer’s disease neurons respond to toxic Aβ oligomers by boosting S100B — a Ca-binding chaperone that protects the cytoskeleton and synapses from damage 🧠Collaboration with the Cardoso Lab, spearheaded by our joint PhD student Joana Saavedra 👩‍🔬👏

📄https://doi.org/10.3389/fnmol.2025.1636365

Design of intrinsically disordered region binding proteins | Science www.science.org/doi/10.1126/...

The second day of talks at #ISPIS2025 #Lisbon finishes with one of our hosts, @claudiogomeslab.bsky.social, telling us about extracellular proteostasis, and the role of S100B as a chaperone holdase in biology and disease

International Symposium on Protein Interactions and self assembly 🇵🇹
📣 Day 2 quick off with @lindorfflarsen.bsky.social talk on Predicting condensates of disordered proteins and many others to follow, poster pitches and session and lakeside lunch. #ISPIS2025 #Lisbon @cienciasulisboa.bsky.social

All set for the start of the 'International Symposium on Protein interactions and self assembly' in Lisbon 🇵🇹 later today. Excited to host an amazing lineup of speakers and 65 participants from all over during the next 3 days #ISPIS2025 @twin2pipsa @cienciasulisboa.bsky.social #ULisboa

Received the 2025 ULisboa/CGD Award in Biomedical Sciences yesterday! 🧪🧠🥼
Thank you to my incredible team and collaborators — and congrats to all fellow awardees!👏

Still time to submit an abstract for a short talk! Join us in Lisbon to discuss all things protein — interactions, aggregation, phase separation, and more! 🗓️ Deadline 30 June

📢 International Symposium on Protein Interactions and Self-Assembly

Join us in ☀️ Lisbon 🇵🇹
🗓️ 14–16 July 2025

🗣️ A great programme + short talks selected from abstracts.

🔗 Check it here: twin2pipsa.campus.ciencias.ulisboa.pt/ISPIS2025.html

🔬 Powered by #TWIN2PIPSA at @cienciasulisboa.bsky.social

Just out! A collaboration with the Herrera lab shows that S100B acts as a chaperone supporting intermediate filament organization, compensating for sacsin loss in a cell model of Autosomal Recessive Spastic Ataxia of Charlevoix–Saguenay (ARSACS) #molecularneurobiology
doi.org/10.1007/s120...

Congratulations to Guilherme Moreira for the brilliant defence of his PhD thesis: “The calcium-binding protein S100B as a novel chaperone preventing Tau aggregation in Alzheimer’s disease” 🧠 Huge thanks to the jury and everyone who came to support! #ProudSupervisor @cienciasulisboa.bsky.social

A new protein sequencing method, which uses a biological motor to pull a protein through a tiny nanopore, could revolutionise protein analysis.
www.chemistryworld.c...

Thrilled to be an invited speaker 🗣️ at the @acs.org Fall 2025
Global Virtual Symposium "Tackling Multifactorial #Alzheimer’s Disease"🧠 .Join us as we explore the latest advances in understanding the complex nature of AD. 📆 Submit your abstract by 31/3/24 🧪
www.acs.org/events/fall/...

Our paper on prediction of phase-separation propensities of disordered proteins from sequence is now published:
www.pnas.org/doi/10.1073/...

The paper has been substantially updated compared to the preprint including new experimental data and using the neural network to finetune CALVADOS. 1/n

Predictomes, a classifier-curated database of AlphaFold-modeled protein-protein interactions

Looking forward #ADAM10 kick-off 🇸🇪 3 days of all things amyloid and great opportunity to meet old friends and making new ones! Thanks @professorpernilla.bsky.social and Elin Esbjorner et al for such a great program. Reach out if you are around
www.chalmers.se/en/conferenc...

Hello Bluesky, we just landed and are happy to reconnect! We research on #proteins and mechanisms of aggregation in #Alzheimer's Disease and #ProteinFolding disorders at ULisboa 🧪 Follow us for news and updates on lab life and achievements 🥼 and check us out at:
🔗 folding.campus.ciencias.ulisboa.pt